Pharmacology Exam: Test Your GK! Quiz

41 Questions | Total Attempts: 121

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Pharmacology Exam: Test Your GK! Quiz

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Questions and Answers
  • 1. 
    This subdivision of the Peripheral Nervous System controls voluntary skeletal movement:
    • A. 

      Efferent Division

    • B. 

      Somatic System

    • C. 

      Parasympathetic System

    • D. 

      Sympathetic System

  • 2. 
    Where is acetylcholine used as a neurotransmitter?
    • A. 

      Pre-ganglionic nerve synapses

    • B. 

      In neuroeffector junctions in the Parasympathetic Nervous System

    • C. 

      Neuroeffector junction of the sympathoadrenal gland in the SNS

    • D. 

      In sweat glands at the sympathetic cholinergic junction

    • E. 

      In the somatic nervous system at the neuromuscular junction

  • 3. 
    Epinephrine is a neurotransmitter released from the adrenal gland.
    • A. 

      True

    • B. 

      False

  • 4. 
    Where are nicotinic receptors located?
    • A. 

      Effectors stimulated by norepinephrine

    • B. 

      Ganglia of SNS & PSNS & neuromuscular junction of the Somatic NS

    • C. 

      Sweat glands innervated by the SNS

  • 5. 
    When the sympathetic system is dominated, what will the effect be on the radial muscle of the eye?
    • A. 

      Relaxation

    • B. 

      Loss of control

    • C. 

      Acceleration

    • D. 

      Constriction

  • 6. 
    What is a way that the Parasympathetic & Sympathetic Nervous Systems "communicate"?
    • A. 

      There is no communication between the two

    • B. 

      They regulate each other's function. For example, when the Sympathetic NS is stimulated, acetylcholine release is decreased by the A2 receptor, leading to further "domination" of the SNS

    • C. 

      They regulate each other's function. For example, when the Sympathetic NS is stimulated, norepinephrine release is decreased by the M5 receptor, leading to further "domination" of the Parasympathetic NS.

  • 7. 
    Smooth muscle in the skin is mediated by ____ stimulation & is thermoregulated.
    • A. 

      A1

    • B. 

      B1

    • C. 

      A2

    • D. 

      B2

  • 8. 
    The parasympathetic NS is termed the "fight or flight system"
    • A. 

      True

    • B. 

      False

  • 9. 
    The dominant parasympathetic/sympathetic tone controlling the bladder at rest is:
    • A. 

      Parasympathetic

    • B. 

      Sympathetic

  • 10. 
    Where does the synthesis of acetylcholine occur?
    • A. 

      Neuroeffector junction of the SNS

    • B. 

      Storage vesicles in the nerve ending

    • C. 

      Cytoplasm of the nerve ending

  • 11. 
    Pseudocholinesterase is selective only for ACh.
    • A. 

      True

    • B. 

      False

  • 12. 
    What happens to the majority of ACh that is released into the synapse of the nerve?
    • A. 

      It is taken back into the cell by a reuptake pump

    • B. 

      It is broken down rapidly by acetylcholinesterase

    • C. 

      It is taken up by the cholinoceptors on the postsynaptic cell & creates action potential

    • D. 

      It goes back into the cell to regulate its own release

  • 13. 
    The final step in the production of norepinephrine occurs in the cytoplasm of the nerve terminal.
    • A. 

      True

    • B. 

      False

  • 14. 
    What is responsible for the breakdown of norepinephrine?
    • A. 

      COMT

    • B. 

      BuChE

    • C. 

      Various esterases

    • D. 

      MAO

  • 15. 
    Which part of the release of ACh does Botox inhibit?
    • A. 

      It inhibits the docking protein that causes the vesicle to dock with the cell membrane and release the contents of the vesicle

    • B. 

      It inhibits the reuptake of acetylcholine, causing it to stay in the synapse for a longer period of time and have a greater therapeutic effect

    • C. 

      It causes the ACh to be released prematurely from the vesicle

    • D. 

      It blocks the regulation of ACh once it is released into the neuroeffector junction, leading to uncontrollable release

  • 16. 
    Why is a small dose of acetylcholine produce minimal effects?
    • A. 

      Cardiovascular compensory reflexes

    • B. 

      The dose is small & rapidly destroyed

    • C. 

      Acetylcholine doesn't produce many effects

    • D. 

      There is prolonged parasympathetic effect

    • E. 

      The sympathetic nerves are stimulated

  • 17. 
    If you are trying to read a paper that is within 4 inches of your face, how does your eye compensate?
    • A. 

      The ciliary muscle contracts, leading to pupillary constriction

    • B. 

      The suspensory ligament relaxes

    • C. 

      The lens of the eye becomes more concave

    • D. 

      The lens of the eye becomes more flat

    • E. 

      The ciliary muscle relaxes, leading to suspensory ligament contraction

  • 18. 
    Direct acting cholinomimetics bind to & activate muscarinic or nicotinic receptors
    • A. 

      True

    • B. 

      False

  • 19. 
    What is a name for a drug that mimicks the action of acetylcholine?
    • A. 

      Cholinomimetics

    • B. 

      Cholinergic agonists

    • C. 

      Parasympathomimetics

    • D. 

      Anticholinergics

    • E. 

      Muscarinic agonists

  • 20. 
    Which kind of nicotinic receptor is stimulated by the Somatic Nervous System?
    • A. 

      Nm

    • B. 

      Nn

  • 21. 
    Where are the M2 cholinoceptor subtype located?
    • A. 

      CNS, SNS cells

    • B. 

      CNS, lung

    • C. 

      CNS

    • D. 

      Heart, neurons, smooth muscle

    • E. 

      Glands, smooth muscle, endothelium

  • 22. 
    Which muscarinic receptors are linked to the Gi (inhibitory) pathway?
    • A. 

      M1

    • B. 

      M2

    • C. 

      M3

    • D. 

      M4

    • E. 

      M5

  • 23. 
    There are muscarinic receptors on blood vessels.
    • A. 

      True

    • B. 

      False

  • 24. 
    Without vagal stimulation, the heart rate is naturally faster. 
    • A. 

      True

    • B. 

      False

  • 25. 
    How are cholinomimetics useful in the treatment of glaucoma?
    • A. 

      The radial muscle is contracted, leading to an escape of aqueous humor through the posterior chamber.

    • B. 

      It leads to contraction of the ciliary muscles, which relaxes the suspensory ligaments of they eye, leading to aqueous humor outflow through the canal of schlemm leading to the anterior chamber.

    • C. 

      Relaxation of the ciliary muscle leads to contraction of the suspensory ligament which leads to decreased IOP

    • D. 

      Cholinomimetics are dangerous to use for the treatment of glaucoma.

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