Pharmacology Exam 2-3

25 Questions

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Pharmacology Quizzes & Trivia

Quiz over information covered on 4/6.


Questions and Answers
  • 1. 
    Adverse drug effects are responsible for what percent of hospital admissions?
    • A. 

      10-15

    • B. 

      5-7

    • C. 

      20-25

    • D. 

      0.5-1

  • 2. 
    ___________ response is a drug response that is unanticipated for the type of drug and its use.
  • 3. 
    TPMT is an enzyme with common genetic defects that affects metabolism of which of the following?
    • A. 

      Azathioprine

    • B. 

      Isoniazid

    • C. 

      Primiquine

    • D. 

      Methotrexate

    • E. 

      Cytochrome p450

  • 4. 
    Which drugs are associated with NAT?
    • A. 

      Cocaine

    • B. 

      Succinylcholine

    • C. 

      Primiquine

    • D. 

      Isoniazid

  • 5. 
    Succinylcholine causes which of the following?
    • A. 

      Coagulation

    • B. 

      Increased heart rate

    • C. 

      Muscle relaxation

    • D. 

      Increased neural function

  • 6. 
    Which is the normal NAT cholinesterase genotype?
    • A. 

      W

    • B. 

      K

    • C. 

      S

    • D. 

      M

  • 7. 
     W/K/S has no cholinesterase activity
  • 8. 
    Due to the effects of cocaine, overdose can cause
    • A. 

      Respiratory arrest

    • B. 

      Excessive bleeding

    • C. 

      Hallucinations

    • D. 

      Stroke

  • 9. 
    Which drug is a treatment for TB?
    • A. 

      Primiquine

    • B. 

      Azathioprine

    • C. 

      Methotrexate

    • D. 

      Isoniazid

  • 10. 
    Isoniazid is a fast/slow acetylator
  • 11. 
    Who was not a TB victim?
    • A. 

      Keats

    • B. 

      Thoreau

    • C. 

      Chopin

    • D. 

      Michael Jackson

    • E. 

      Paganini

  • 12. 
    What infectious disease is the leading cause of death worldwide?
    • A. 

      Malaria

    • B. 

      TB

    • C. 

      HIV

    • D. 

      Measles

  • 13. 
    Isoniazid is a phase I/II metabolism drug
  • 14. 
    Isoniazid acetylation occurs in the
    • A. 

      Liver

    • B. 

      Gut

    • C. 

      Lung

    • D. 

      Kidney

  • 15. 
    N-acetylation involves transfer of acetyl group from ________________.
  • 16. 
    Isoniazid inhibits ___________ acid, which is unique to M. tuberculosis.
  • 17. 
    Isoniazid is a(n) enteral/parenteral/both/neither drug
  • 18. 
    Which form of malaria is life-threatening?
    • A. 

      P. malariae

    • B. 

      P. vivax

    • C. 

      P. falciparum

    • D. 

      P. ovale

  • 19. 
    Which drug is used to treat malaria?
    • A. 

      Isoniazid

    • B. 

      Primiquine

    • C. 

      Azathioprine

    • D. 

      Methotrexate

  • 20. 
    Primaquine is not effective in which stage of P. falciparum?
    • A. 

      Hepatic

    • B. 

      Latent

    • C. 

      Erythrocytic

  • 21. 
    Patients with G-6-P dehydrogenase deficiency may experience what adverse effect when taking primaquine?
    • A. 

      Diarrhea

    • B. 

      Arrhythmias

    • C. 

      Acidosis

    • D. 

      Hemolytic anemia

  • 22. 
    G-6-PD deficiency is a(n) ______ deficiency
    • A. 

      Autosomal recessive

    • B. 

      Autosomal dominant

    • C. 

      Sex-linked

  • 23. 
    G-6-PD deficiency is not prevalent in which of the following populations?
    • A. 

      Western European

    • B. 

      African

    • C. 

      Mediterranean

    • D. 

      Oriental

  • 24. 
    6-Mercaptopurine and azathioprine are drugs used to treat
    • A. 

      Childhood leukemia

    • B. 

      Fungal infections

    • C. 

      Autoimmune diseases

    • D. 

      Sepsis

  • 25. 
    Metabolite build up experienced in people with TPMT deficiency is especially toxic to the
    • A. 

      Liver

    • B. 

      Kidney

    • C. 

      Bone marrow

    • D. 

      Brain