Pharmacology Exam 2-2

30 Questions

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Pharmacology Quizzes & Trivia

Quiz for information covered 4/5/2010, hour 1.


Questions and Answers
  • 1. 
    TI is
    • A. 

      LD50/ED50

    • B. 

      ID50/ED50

    • C. 

      ED50/LD50

    • D. 

      AD50/ID50

  • 2. 
    _______% of psychiatric patients are treated with "off label" drug use
    • A. 

      20%

    • B. 

      30%

    • C. 

      31%

    • D. 

      50%

    • E. 

      75%

  • 3. 
    True or false: drug manufacturers are prohibited by law from promoting off label use of their drugs to physicians
  • 4. 
    Digitalis glycosides (digoxin) may cause which of the following side effects
    • A. 

      Hypotension

    • B. 

      Excessive bleeding

    • C. 

      Hypoglycemia

    • D. 

      Arrhythmias

  • 5. 
    Which antagonists works as an antihypertensive?
    • A. 

      Beta 1

    • B. 

      Alpha 1

    • C. 

      Beta 2

    • D. 

      Alpha 2

  • 6. 
    Reye's syndrome can be an adverse side effect of
    • A. 

      Antipsychotics

    • B. 

      Raptiva

    • C. 

      Rofecoxib

    • D. 

      Aspirin

  • 7. 
    Stage VI of Reye's syndrome is defined by
    • A. 

      Nausea

    • B. 

      Stupor

    • C. 

      Fever

    • D. 

      Spontaneous combustion

  • 8. 
    All of the following are side effects of efalizumab (Raptiva) except for
    • A. 

      PML

    • B. 

      Viral meningitis

    • C. 

      Tardive dyskinesia

    • D. 

      Fungal disease

    • E. 

      Sepsis

  • 9. 
    Tardive dyskinesia is a side effect of
    • A. 

      Analgesics

    • B. 

      NSAIDS

    • C. 

      Antipsychotics

    • D. 

      Anticoagulants

  • 10. 
    ________ is a drug used to treat arthritis and chronic/acute pain
  • 11. 
    Reactive drug metabolites are usually detoxified by either ___________ or __________. Name one.
  • 12. 
    _______ converts superoxide anions to oxygen + hydrogen peroxide
  • 13. 
    Alcohol uses up this energy supply that would usually be used to digest drugs
    • A. 

      NADPH

    • B. 

      ATP

    • C. 

      FADH2

    • D. 

      NADH

  • 14. 
    The oxidized form of glutathione is
    • A. 

      GSH

    • B. 

      GSSG

  • 15. 
    Glutathione reductase requires
    • A. 

      Riboflavin

    • B. 

      Selenium

    • C. 

      NADH

    • D. 

      Cysteine

  • 16. 
    Glutathione is oxidized/reduced in conversion of H2O2 to water
  • 17. 
    GSH's primary biological function is to act as a(n)
    • A. 

      Enzymatic reducing agent

    • B. 

      Enzymatic oxidizing agent

    • C. 

      Non-enzymatic reducing agent

    • D. 

      Non-enzymatic oxidizing agent

  • 18. 
    GSH maintains what type of side chains?
  • 19. 
    High levels of cystine are associated with
    • A. 

      Muscle rigidity

    • B. 

      Lung disease

    • C. 

      Heart disease

    • D. 

      Renal failure

  • 20. 
    The monomer/dimer of cysteine has physiological function
  • 21. 
    Which are antioxidants (choose all that apply)?
    • A. 

      Vitamin D

    • B. 

      Vitamin E

    • C. 

      Vitamin C

    • D. 

      Vitamin A

  • 22. 
    Which of the following is not an NSAID?
    • A. 

      Aspirin

    • B. 

      Ibuprofen

    • C. 

      Tylenol

    • D. 

      Aleve

  • 23. 
    NSAIDs in chronic high dose use can cause
    • A. 

      Renal failure

    • B. 

      Hepatotoxicity

  • 24. 
    Renal failure by NSAIDs is reversible/irreversible, hepatotoxicity is reversible/irreversible
    • A. 

      Reversible, reversible

    • B. 

      Reversible, irreversible

    • C. 

      Irreversible, irreversible

    • D. 

      Irreversible, reversible

  • 25. 
    Cyclosporine (CSA) is a(n)
    • A. 

      Antineoplastic drug

    • B. 

      Analgesic

    • C. 

      Teratogen

    • D. 

      Immunosuppressant

  • 26. 
    Which drugs affect histogenesis and maturation?
    • A. 

      Alcohol

    • B. 

      Cytotoxic drugs

    • C. 

      Steroids

  • 27. 
    Cyclophosphamide is a(n)
    • A. 

      Antimetabolite

    • B. 

      Purine analog

    • C. 

      Folic acid inhibitor

    • D. 

      Alkylating agent

  • 28. 
    Methotrexate is a(n)
    • A. 

      Antimetabolite

    • B. 

      Purine analog

    • C. 

      Folic acid inhibitor

    • D. 

      Alkylating agent

  • 29. 
    Minamate disease is caused by
    • A. 

      High levels of vitamin A

    • B. 

      High levels of methylmercury

    • C. 

      High levels of lead

    • D. 

      High levels of cadmium

  • 30. 
    Alcohol interference with vitamin ____ is involved in FAS