Drug Metabolism quiz.
Bioavailability
Biotransformation
Enzyme induction
Enzyme inhibition
None of the above
Hydrolysis
Oxidation
Reduction
Mitomycin C
Ketoconazole
Isoniazid
Tamoxifen
Morphine
Mitomycin C
Ketoconazole
Isoniazid
Ethanol
Morphine
UDP-glucuronosyl transferase
N-acetyltransferase
Pseudocholinesterase
Vitamin K epoxide reductase
Alcohol dehydrogenase
Bilirubin encephalopathy
Neonatal jaundice
Kernicterus
A and B
All of the above
Phototherapy
Barbiturate phenobarbital
N-acetylcysteine
A and B
All of the above
Increase the amount of isozymes and increase metabolism
Decrease the amount of isozymes and increase metabolism
Increase the amount of isozymes and decrease metabolism
Decrease the amount of isozymes and decrease metabolism
None of the above
CYP3A4 inhibitor
Slow acetylators
Suicide inhibitors
P-gp inhibitors
None of the above
Single nucleotide polymorphism
Slow acetylators
Smoking
P-glycoprotein
Grapefriut juice
Increased
Decreased
The same
Cannot be determined
Single nucleotide polymorphism
Slow acetylators
Smoking
P-glycoprotein
Grapefriut juice
Single nucleotide polymorphism
Slow acetylators
Smoking
P-glycoprotein
Grapefriut juice
If she also takes a CYP3A4 inducer
If she also takes a CYP3A4 inhibitor
She cannot get pregnant
Cannot predict
UDP-glucuronosyl transferase
N-acetyltransferase
Pseudocholinesterase
Vitamin K epoxide reductase
Alcohol dehydrogenase
Phototherapy
Barbiturate phenobarbital
N-acetylcysteine
A and B
All of the above
Phototherapy
Barbiturate phenobarbital
N-acetylcysteine
A and B
All of the above
Slow acetylators
Fast metabolizers
Ultra metabolizers
B and C
All of the above
Ketoconazole
Tamoxifen
Carbamazepine
Mitomycin C
Losartan
Ketoconazole
Tamoxifen
Carbamazepine
Mitomycin C
Losartan
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