Pharm Tech Chapter 11 (Factors Affecting Drug Activity)

44 Questions | Total Attempts: 208

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Drug Quizzes & Trivia

Human variablitiy, disease states, adverse drug reations, drug-drug intereactions, drug-diet intereactions


Questions and Answers
  • 1. 
    When two different molecules associate or attached to each other
    • A. 

      Cirrhosis

    • B. 

      Complexation

    • C. 

      Enzyme induction

    • D. 

      Enzyme inhibition

  • 2. 
    An abnormal sensitivity generally resulting in an allergic reaction
    • A. 

      Hypersensitivity

    • B. 

      Hyposensitivity

    • C. 

      Isonotonixty

    • D. 

      Just crazy

  • 3. 
    A potentialyl fatal hypersensitivity reaction producting severe respiratiory distress and cardiovascular collapse.
    • A. 

      Heart pain

    • B. 

      Cirrhosis

    • C. 

      Anaphylactic shock

    • D. 

      Gas

  • 4. 
    An unexpected reaction the first time a drug is taken, generaly due to genetic causes
    • A. 

      Idiosynscrasy

    • B. 

      Displacement

    • C. 

      Synergism

    • D. 

      Antidote

  • 5. 
    The ability of a substance to cause cancer
    • A. 

      Carcinogenicity

    • B. 

      Cirrhosis

    • C. 

      Antidote

    • D. 

      Complexation

  • 6. 
    When two drugs with a similar pharmacological actions result in an effect equal to the sum of the individiual effects
    • A. 

      Additive effects

    • B. 

      Adverse effect

    • C. 

      Cause and effect

    • D. 

      Effects of some kind, i dont know

  • 7. 
    When two drugs with similar pharmacological actions produce greater effects than the sum of the individual effects
    • A. 

      Synergism

    • B. 

      Hypersensitivity

    • C. 

      Painful

    • D. 

      None of the above

  • 8. 
    A drug that antagonizes the toxic effect of another drug
    • A. 

      Antidote

    • B. 

      Adverse drug reaction

    • C. 

      Idiosyncrasy

    • D. 

      Synergism

  • 9. 
    A chronic and potentially fatal liver disease causing loss of function and increased resistance to blood flow through the liver
    • A. 

      Complexatoin

    • B. 

      Infection of the nerves

    • C. 

      Cirrhosis

    • D. 

      None of the above

  • 10. 
    An inflammatory condition of the liver caused by viruses
    • A. 

      Antidote

    • B. 

      Cancer

    • C. 

      Acute viral hepatitis

    • D. 

      All the above

  • 11. 
    When the elements of ingested nutrients interact with a drug and this affects the disposition of the drug
    • A. 

      Drug-diet interactions

    • B. 

      Enzyme induction

    • C. 

      Enzyme inhibition

    • D. 

      None of the above

  • 12. 
    An obstruction of bile duct that causes hepatic waste products and the bile to accumulate in the liver
    • A. 

      Gas

    • B. 

      Obstruction jaundice

    • C. 

      Enzyme induction

    • D. 

      Pain

  • 13. 
    A condition in which thyroid secretions are below normal, often referred to as an underactive thyroid
    • A. 

      Hypothyroidism

    • B. 

      Hypersensitivity

    • C. 

      Hyperthyroidism

    • D. 

      Hyposensitivity

  • 14. 
    A condition in which thyroid secretioins are below normal, often referred to as an underactive thyroid
    • A. 

      Hypothyroidism

    • B. 

      Hypersensitivity

    • C. 

      Hyperthyroidism

    • D. 

      Hyposensitivity

  • 15. 
    A field of study which defines the hereditary basis of individual differences in the ADME processes
    • A. 

      Pharmacogenetics

    • B. 

      Pharmacopia

    • C. 

      Chapter

    • D. 

      None of the above

  • 16. 
    An uninteded side effecto fo a mediation that is negative or in some way injurious to the patient's healthy
    • A. 

      Cirrhosis

    • B. 

      Potentiation

    • C. 

      Synergism

    • D. 

      Adverse drug reaction

  • 17. 
    An effect produced when one drug with no inherent activity of its own increases the activity of another drug
    • A. 

      Potentiation

    • B. 

      Synergism

    • C. 

      Diet drug issues

    • D. 

      All the above

  • 18. 
    A drug bound to a plasma protien is removed when another drug of greater binding potential binds to the same protient
    • A. 

      Complexation

    • B. 

      Displacement

    • C. 

      Enzyme inhibition

    • D. 

      Potentiation

  • 19. 
    The decrease in hypatic enzyme activity that resuts in reduced metabolism of drugs
    • A. 

      Enzyme induction

    • B. 

      Enzyme inhibition

    • C. 

      Hypersensitivity

    • D. 

      Hyposensitivity

  • 20. 
    The increase inhepatic enzyme activity that resuts in greater metabolism of drugs
    • A. 

      Enzyme induction

    • B. 

      Enzyme inhibition

    • C. 

      Hypersensitivity

    • D. 

      Hyposensitivity

  • 21. 
    Drug distribution, metabolism, and excretion are quite different in ____ than in adults because their organ systems are not fully developed
    • A. 

      Infants and adolescents

    • B. 

      Neonates and infants

    • C. 

      Children and adolescents

    • D. 

      Elders

  • 22. 
    Children between the ages of _____ metabolize certain drugs more rapidly than adults
    • A. 

      0 and 6 months

    • B. 

      6 and 18 months

    • C. 

      1 and 2 years

    • D. 

      1 and 12 years

  • 23. 
    Which  physiological change is typically seen with pregnant women that affects drug disposition
    • A. 

      Decreased rate of absorption

    • B. 

      Decreased urinary excretion

    • C. 

      Increased plasma protein binding

    • D. 

      Decreased rate of metabolism

  • 24. 
    The distribution of drugs may be different between men and women due to
    • A. 

      Normal fluctuations

    • B. 

      Age

    • C. 

      Body composition

    • D. 

      Activity

  • 25. 
    The placebo effect is a
    • A. 

      Psychological variable

    • B. 

      Gender variable

    • C. 

      Hypersensitive reaction

    • D. 

      Drug dependence variable

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