Panevelil #3

35 Questions | Total Attempts: 92

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Panevelil #3

A review for test #3 for Dr. Panevelil's pharm class.


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Questions and Answers
  • 1. 
    Which form of diabetes is considered to be 'insulin dependent'?
    • A. 

      Type 1

    • B. 

      Type 2

    • C. 

      Both types, depending on severity

    • D. 

      Neither type.

  • 2. 
    Which of the following insulins is conjugated with protamine so that it may have an intermediate duration of action?
    • A. 

      Regular

    • B. 

      NPH

    • C. 

      Ultralente

    • D. 

      Glipozide

  • 3. 
    Which of the following is a long acting insulin?
    • A. 

      Regular

    • B. 

      NPH

    • C. 

      Ultralente

    • D. 

      Metformin

  • 4. 
    Which of the following drugs is a 2nd generation sulfonylurea?
    • A. 

      Glimepride

    • B. 

      Repaglinide

    • C. 

      Metformin

    • D. 

      Acarbose

  • 5. 
    Which of the following drugs is a meglitinide that binds to ATP-sensitive potassium channels in pancreatic beta cells thus causing the release of insulin?
    • A. 

      Glyburide

    • B. 

      Repaglinide

    • C. 

      Metformin

    • D. 

      Rosiglitazone

  • 6. 
    What is the MOA of Acarbose?
    • A. 

      Stimulation of insulin release from beat cells of pancreas

    • B. 

      Enhances tissue senstivity to insulin through agonism of PPAR-gamma receptors.

    • C. 

      Inhibits alpha-glucosidase in the intestinal brush border and thus decreases absorption of starch and disaccharides

    • D. 

      DDP-IV antagonism which results in greatly lowered HbA-1c levels

  • 7. 
    Which drug used in the treatment of diabetes is a biguranide and can also lower cholesterol and has been found to help many patients lose weight?
    • A. 

      Metformin

    • B. 

      Acarbose

    • C. 

      Sitagliptin

    • D. 

      Glipizide

  • 8. 
    What is the mechanism of action of Penicillins?
    • A. 

      Inhibit cross linking step in synthesis of bacterial cell wall.

    • B. 

      Inhibition of beta lactamase

    • C. 

      They bind to 30S ribosomal RNA thus inhibiting bacterial protein synthesis

    • D. 

      Inhibits alpha-glucosidase in the intestinal brush border

  • 9. 
    Which drug is considered a first line treatment against syphillis?
    • A. 

      Vancomycin

    • B. 

      Penicillin

    • C. 

      Ceftriaxone

    • D. 

      Rifampin

  • 10. 
    How are the penicillins eliminated from the body?
    • A. 

      Through the liver

    • B. 

      Through digestive tract

    • C. 

      Through the kidneys

    • D. 

      A combination of all the above.

  • 11. 
    Which of the following is an extended spectrum penicillin which is the treatment of choice for aerobic gram positive bacilli?
    • A. 

      Clavulanic Acid

    • B. 

      Oxacillin

    • C. 

      Cefepime

    • D. 

      Ampicillin

  • 12. 
    Which of the penicillins has the highest incidence of hypersensitivity?
    • A. 

      Ampicillin

    • B. 

      Penicillin G

    • C. 

      Methicillin

    • D. 

      Nafcillin

  • 13. 
    Which of the following is a beta lactamase inhibitor?
    • A. 

      Cefaclor

    • B. 

      Clavulanic Acid

    • C. 

      Ticarcillin

    • D. 

      Doxycycline

  • 14. 
    All cephalosporins are active against...
    • A. 

      Anearobic bacteria

    • B. 

      Gram negative cocci & bacilli

    • C. 

      Gram positive cocci & bacilli

    • D. 

      Both gram negative & positive spirochetes

  • 15. 
    Which of the following is the FIRST drug of choice for surgical prophylaxis?
    • A. 

      Cleocin

    • B. 

      Gentamycin

    • C. 

      Unasyn

    • D. 

      Cefazolin

  • 16. 
    How are third generation cephalosporins different from first and second generation cephalosporins?
    • A. 

      Ability to cross the blood brain barrier

    • B. 

      Greater activity against gram positive cocci & enterobacter

    • C. 

      Far less likely to cause hypersensitivity reactons

    • D. 

      Are not widely available within the US.

  • 17. 
    Which of the following is considered a first line treatment for gonorrhea?
    • A. 

      Gentamycin

    • B. 

      Ceftriaxone

    • C. 

      Penicillin

    • D. 

      Primaxin

  • 18. 
    Third generation cephalosporins can be used to treat all of the following EXCEPT:
    • A. 

      CNS infections

    • B. 

      Gonorrhea

    • C. 

      Enterobacter

    • D. 

      P. aeruginosa

  • 19. 
    Which of the following is a cephalosporin useful against enterobacter?
    • A. 

      Cefazolin

    • B. 

      Ceftriaxone

    • C. 

      Cefaclor

    • D. 

      Cefepime

  • 20. 
    All cephalosporins start with...
    • A. 

      Cef-

    • B. 

      Pen-

    • C. 

      Myc-

    • D. 

      Roc-

  • 21. 
    What is the broadest spectrum beta lactam antibiotic available?
    • A. 

      Zosyn

    • B. 

      Primaxin

    • C. 

      Cefepime

    • D. 

      Oxacillin

  • 22. 
    Which of the following could you use to treat an uncomplicated UTI in a pregnant woman?
    • A. 

      Fosfomycin

    • B. 

      Ciprofloxacin

    • C. 

      Cefonazid

    • D. 

      Cycloserine

  • 23. 
    Which of the following may only be given topically due to its known nephrotoxicity when given systemically?
    • A. 

      Tetracycline

    • B. 

      Bacitracin

    • C. 

      Azithromycin

    • D. 

      Fosfomycin

  • 24. 
    What is the only cell wall synthesis inhibitor used almost exclusively in the treatment of Tuberculosis?
    • A. 

      Rifampin

    • B. 

      Vancomycin

    • C. 

      Cycloserine

    • D. 

      Clarithromycin

  • 25. 
    Tetracyclines almost all end in...
    • A. 

      -cef

    • B. 

      -cillin

    • C. 

      -ipime

    • D. 

      -cycline