Pharmaceutics Exam Questions Quiz

128 Questions

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Pharmaceutics Exam Questions Quiz

Here are the questions from our Ceutics exams plus some others.


Questions and Answers
  • 1. 
    A direct compression process to make tablets can only be used for drugs that are heat sensitive, light sensitive or moisture sensitive.
    • A. 

      True

    • B. 

      False

  • 2. 
    Patients should not take an antacid product along with an enteric coated tablet.
    • A. 

      True

    • B. 

      False

  • 3. 
    A non-steroidal anti-inflammatory drug, such as aspirin, is enterically coated to stabilize the aspirin against degradation in the acidic environment of the stomach.
    • A. 

      True

    • B. 

      False

  • 4. 
    A drug must first dissolve in the GI fluid before absorption from a tablet dosage form can occur.  Soft gelatin capsules may contain oily solutions of drugs
    • A. 

      True

    • B. 

      False

  • 5. 
    The Pellicle effect seen with hard gelatin capsules is not a problem with HPMC. Drugs are typically more stable in aqueous solution than they are in the dry state.
    • A. 

      True

    • B. 

      False

  • 6. 
    Allegra D is a bilayer tablet product whereas Effexor XR is an extended release capsule product containing coated pellets.
    • A. 

      True

    • B. 

      False

  • 7. 
    The results of the Phase 1 clinical trial need to be approved by the FDA before an IND is submitted for review to the FDA.
    • A. 

      True

    • B. 

      False

  • 8. 
    Lactose and dicalcium phosphate are the two most common diluents presently in commercial tablet and capsule formulations.
    • A. 

      True

    • B. 

      False

  • 9. 
    Enteric polymers are insoluble in acid and dissolve at pH 5.5 and above release the contents of the coated pellet, tablet or capsule in the duodenum and the upper small intestine.
    • A. 

      True

    • B. 

      False

  • 10. 
    Deliquescent drugs should not be formulated into hard gelatin capsules.
    • A. 

      True

    • B. 

      False

  • 11. 
    Magnesium stearate and stearic acid are the two most common lubricants utilized by innovator and generic pharmaceutical companies in commercial tablet formulations.
    • A. 

      True

    • B. 

      False

  • 12. 
    Efflorescent granules are typically comprised of citric acid and tartaric acid in combination with sodium bicarbonate.
    • A. 

      True

    • B. 

      False

  • 13. 
    Drugs with a high therapeutic index will have a low MTC and a high MEC
    • A. 

      True

    • B. 

      False

  • 14. 
    A major difference between ANDA and a NDA is that the NDA contains some stability data on the finished product.
    • A. 

      True

    • B. 

      False

  • 15. 
    Eutectic formation results when water is absorbed into an excipient resulting in an increase in the number of water molecules in the crystal and increasing the hardness of tablets following compression.
    • A. 

      True

    • B. 

      False

  • 16. 
    The slugging or recompression method of tablet manufacture can be used to make tablets containing drugs that are unstable in the presence of moisture.
    • A. 

      True

    • B. 

      False

  • 17. 
    Sporanox capsules contain coated beads that are not formulated to sustain the release of the active ingredient (Itraconazole).
    • A. 

      True

    • B. 

      False

  • 18. 
    The surface area of a powder increases when the particle size is decreased.
    • A. 

      True

    • B. 

      False

  • 19. 
    A thermolabile drug is one that is unstable to heat.  Lamination or capping of a tablet can results from poor bonding between granules in a tablet compact.
    • A. 

      True

    • B. 

      False

  • 20. 
    The Angle of Repose is a physical property of a powder that is used as a measure of flow.  As the Angle of Repose decreases, the flow properties increase.
    • A. 

      True

    • B. 

      False

  • 21. 
    Soft gelatin capsules are very useful dosage forms to deliver drugs that are poorly soluble in water.  Which one of the following vehicles CANNOT be used in soft gelatin capsules
    • A. 

      Miglyol 812

    • B. 

      Peanut oil

    • C. 

      Purified water

    • D. 

      Castor oil

    • E. 

      Polyethylene glycol

  • 22. 
    Select the one correct answer
    • A. 

      A ball mill may be used to increase the surface area of a solid drug substance

    • B. 

      The transit time in the stomach is always longer than the transit time for a dosage form in the small intestine

    • C. 

      Talc is often used in capsule formulations to promote wetting of the powder and dissolution of the drug substance, following the disintegration of the hard gelatin capsule

    • D. 

      Powders are ideal dosage forms for unpleasant tasting drugs

  • 23. 
    CONI-Snap capsules offer significant advantages over traditional hard gelatin capsules in overcoming problems related to deliquescence.
    • A. 

      True

    • B. 

      False

  • 24. 
    Ac-Di-Sol is a superdisintegrant for tablets and releases carbon dioxide during the dissolution process.
    • A. 

      True

    • B. 

      False

  • 25. 
    Granules are irregular agglomerates fo small particles which behave as a single large particle.
    • A. 

      True

    • B. 

      False

  • 26. 
    The Noyes-Whitney equation is a very effective method to determine the particle size of the drug as a function of temperature
    • A. 

      True

    • B. 

      False

  • 27. 
    The primary reason for companies to formulate drugs into granules for reconstitution by the pharmacist is to decrease costs by eliminating water from the product.
    • A. 

      True

    • B. 

      False

  • 28. 
    The drug present in an enteric coated tablet is primarily absorbed in the small intesting following dissolution of the coating in the stomach.
    • A. 

      True

    • B. 

      False

  • 29. 
    Drugs that are not stable in light are said to degrade by a photolytic degradation process.
    • A. 

      True

    • B. 

      False

  • 30. 
    Drugs classified as BCS I are more soluble than drugs classified as BCS II or BCS IV
    • A. 

      True

    • B. 

      False

  • 31. 
    Hydrochloride salts are the most common salts found in commercial drug products.
    • A. 

      True

    • B. 

      False

  • 32. 
    Clarithromycin for Oral Suspension must be reconstituted by the pharmacist before dispensing the product to the patient
    • A. 

      True

    • B. 

      False

  • 33. 
    The Hatch-Waxman Act sets forth the process by which would-be marketers of generic drugs can file abbreviated new drug applications and seek FDA approval of the generic product
    • A. 

      True

    • B. 

      False

  • 34. 
    Vegicaps are made from HPMC and contain no animal matter and are suitable for both vegetarians and vegans
    • A. 

      True

    • B. 

      False

  • 35. 
    Omeprazole is unstable in acid media
    • A. 

      True

    • B. 

      False

  • 36. 
    Which one of the following companies is NOT a generic pharmaceutical company?
    • A. 

      Ranbaxy

    • B. 

      Dr. Reddy's

    • C. 

      Mylan

    • D. 

      Merck

    • E. 

      Watson

  • 37. 
    Prodrug is a term used to describe a compound that requires metabolic biotransformation after administration to produce the pharmacologically active compound
    • A. 

      True

    • B. 

      False

  • 38. 
    Comminution is a proces that protects the drug from being degraded in the presence of light and moisture
    • A. 

      True

    • B. 

      False

  • 39. 
    High molecular weight hypromellose (HPMC) is used in a matrix tablet to retard the dissolution rates of drugs, whereas low molecular weight hypromellose is used to coat immediate relase tablets.
    • A. 

      True

    • B. 

      False

  • 40. 
    Friability, tablet hardness and tablet weight uniformity are all physical properties of compressed tablets
    • A. 

      True

    • B. 

      False

  • 41. 
    Recompression or slugging involves more compression and drying steps than direct compression in the manufacture of tablets
    • A. 

      True

    • B. 

      False

  • 42. 
    Levaquin, a fluoroquinolone, is levofloxacin hemihydrate
    • A. 

      True

    • B. 

      False

  • 43. 
    Medicated powders are powders of mixtures of finely divided particles in dry form for either internal or external use
    • A. 

      True

    • B. 

      False

  • 44. 
    Lupron contains leuprolide acetate and is used for the treatment of prostate cancer
    • A. 

      True

    • B. 

      False

  • 45. 
    The absorption of doxycycline hyclate is significantly higher in the colon than in the upper small intestine
    • A. 

      True

    • B. 

      False

  • 46. 
    Which one of the following drugs is the most stable in gastric juice?
    • A. 

      Omeprazole

    • B. 

      Insulin

    • C. 

      Aspririn

    • D. 

      Pantoprazole

    • E. 

      Lanoprazole

  • 47. 
    Which salt of amlodipine is present in Norvasc?
    • A. 

      Mesylate

    • B. 

      Acetate

    • C. 

      Sulfate

    • D. 

      Besylate

    • E. 

      Hydrochloride

  • 48. 
    Which of the following ingrediens in a capsule formulation will increase and enhance drug dissolution rate, break up agglomerates and help offset the hydrophobic effects of lubricants
    • A. 

      Sodium lauryl sulfate

    • B. 

      Magnesium stearate

    • C. 

      Talc

    • D. 

      Stearic acid

    • E. 

      Dicalcium sulfate

  • 49. 
    Regarding the use of oral liquid vehicles to compound a 30-day supply of Alprazolam (solubility in water is 45 mcg/mL at 25*C and solubility in EtOH is >20 mg/mL at 25*C), if the contents of Alprazolam capsules sufficient to make a 10mg/mL liquid product were emptied into a mortar and comminuted with a pestle to obtain a fine powder and then mixed with Simple Syrup NF, the resulting extemporaneously prepared product is a suspension
    • A. 

      True

    • B. 

      False

  • 50. 
    For colloidal dispersions, flow is an important property. Glycerin and diluted Simple Syrup NF exhibit Newtonian flow, meaning the rate of shear is linearly related to shearing stress.
    • A. 

      True

    • B. 

      False

  • 51. 
    Shear thinning materials, such as hydroxypropyl methylcellulose dissolved in water at room temperature, exhibit a yield value
    • A. 

      True

    • B. 

      False

  • 52. 
    Methylcellulose at a 2% concentration in purified water is neutrally charged, where as Alginic Acid at a 0.5% concentration is negatively charged in purified water.
    • A. 

      True

    • B. 

      False

  • 53. 
    Acceptable properties of aqueous suspensions include the following: The suspension vehicle should be viscous enough so that the patient gets a uniform dose, but not so viscous to prevent pouring
    • A. 

      True

    • B. 

      False

  • 54. 
    When Cilostazol, a water-insoluble crystalline drug substance, was dosed in an aqueous suspension to beagle dogs, it was found that the 220 nm diamter particle size of Cilostazole had greate bioavailability than the 13 micron diameter particle size
    • A. 

      True

    • B. 

      False

  • 55. 
    When Fenofibrate was administered orally as an aqueous suspension to rats, it was found that Fenofibrate formulated as a nanosuspension by the DissoCube process had equivalent dissolution and bioavailability compared to the Fenofibrate formulated as a microsuspension in Simple Syrup NF
    • A. 

      True

    • B. 

      False

  • 56. 
    When fenofibrate was administered orally as an aqueous suspension to rats, it was found that the DissoCube method produced 338nm diameter particles of Fenofibrate, which had a greater dissolution and bioavailability compaired to fenofibrate formulated as a microsuspension in a vehicle containing 0.4% HEC 400 in NS
    • A. 

      True

    • B. 

      False

  • 57. 
    Examples of viscosity enhancing agents appropriate for topically applied aqueous suspensions include magnesium aluminum silicate (i.e. Veegum) and sodium carboxymethylcellulose
    • A. 

      True

    • B. 

      False

  • 58. 
    An example of a viscosity enhancing suspending agent appropriate for orally administered aqueous suspensions is acacia
    • A. 

      True

    • B. 

      False

  • 59. 
    The rate of settling of a dispersed drug in an aqueous vehicle is increased as the diameter of the drug is increased.
    • A. 

      True

    • B. 

      False

  • 60. 
    When selecting a suspending agent to retard particle settling and promote dispersion stability, the suspending agent and the drug substance must be chemically compatible
    • A. 

      True

    • B. 

      False

  • 61. 
    Cellulose derivatives, such as methylcellulose, are hydrophilic polymers used in both internally administered and externally applied suspensions
    • A. 

      True

    • B. 

      False

  • 62. 
    Amphiphilic molecules used to stabilize pharmaceutical emulsions are not completely hydrophobic or hydrophilic
    • A. 

      True

    • B. 

      False

  • 63. 
    According to the descriptive terms of solubility used by the USP, if Cisapride is practically insoluble in water, then more than 10,000mL of water is requied to dissolve 1g of Cisapride
    • A. 

      True

    • B. 

      False

  • 64. 
    The Noyes-Whitney equation describes mathmatically the relationship between the shear stress (F/A) and the shear rate (dv/dx); and the viscosity of a Newtonian liquid is constant at a given temperature.
    • A. 

      True

    • B. 

      False

  • 65. 
    Plastic flowing liquids exhibit a yield value when shear stress is plotted on the Y-axis and shear rate is plotted on the X-axis; and plastic flowing liquids are elastic below the yield value
    • A. 

      True

    • B. 

      False

  • 66. 
    The Zeta Potential is a measure of the magnitude of the repulsion or attraction between dispersed particles
    • A. 

      True

    • B. 

      False

  • 67. 
    The rate of settling of drug particles suspended in an aqueous vehicle is controlled by the radius of the drug particles, the viscosity of the dispersion medium and the difference between the density of the aqueous vehicle and the density of the drug substance
    • A. 

      True

    • B. 

      False

  • 68. 
    Drug dissolved in an aqueous vehicle is susceptible to particle growth due to Ostwald ripening
    • A. 

      True

    • B. 

      False

  • 69. 
    Flocculating agents are used in drug suspensions to associate the drug particles into tightly packed aggregates and cake which are very difficult to break apart and redisperse through mechanical agitation such as shaking
    • A. 

      True

    • B. 

      False

  • 70. 
    Typical buffering agents used to control the pH of an aqueous suspension vehicle include Citric Acid
    • A. 

      True

    • B. 

      False

  • 71. 
    Emulsions are thermodynamically stable liquid preparations that must be formulated with emulsifying agents, such as Tween 80, in order to increase the interfacial tension between the two immiscible liquids
    • A. 

      True

    • B. 

      False

  • 72. 
    If Vibramysicn Oral Suspension, which contains doxycycline calcium, contains the excipient sodium carboxymethylcellulose, then it is employed as a suspending agent and thickening agent in the suspension
    • A. 

      True

    • B. 

      False

  • 73. 
    Aqueous suspensions are heterogeneous systems in which the particles should not settle rapidly.  This is an acceptable property of aqueous suspensions
    • A. 

      True

    • B. 

      False

  • 74. 
    The rate of dissolution of a drug that is classified as "insoluble" in water is dependent on the agitation conditions being used to dissolve the drug
    • A. 

      True

    • B. 

      False

  • 75. 
    The rate of dissolution of fentanyle in purified water at 37*C depends on its particle size and the degree of agitation being used to stir the system
    • A. 

      True

    • B. 

      False

  • 76. 
    The solubility of fentanyl in purified water at 37*C is greater than the solubility of fentanyl citrate in purified water at 37*C
    • A. 

      True

    • B. 

      False

  • 77. 
    Dehydrated Alcohol USP should be used to extemporaneously compound prescriptions when "essentially water free" alcohol is required
    • A. 

      True

    • B. 

      False

  • 78. 
    Diazepam, the active pharmaceutical ingredient in Valium Injection 5mg/mL is "insoluble" in water at 25*C. This qualitative description of diazepam's solubility is understood to mean that more than 10,000ml of water are required to dissolve 1g of diazepam at 25*C.
    • A. 

      True

    • B. 

      False

  • 79. 
    Epivir Oral Solution contains the co-solvent, propylene glycol, because the API, lamivudine, is only "sparingly soluble" in water at 25*C
    • A. 

      True

    • B. 

      False

  • 80. 
    Ability Oral solution, whihc contains aripiprazole as the API is "practically insoluble" in water at 25*C, and its solubility is pH dependent
    • A. 

      True

    • B. 

      False

  • 81. 
    The rate of dissolution of 150 micron sized particles of Phenobarbital is less than the rate of dissolution of 710 micron sized particles of Phenobarbital in water at 37*C
    • A. 

      True

    • B. 

      False

  • 82. 
    The rate of dissolution of fentanyl citrate in a 50:50 v/v water:ethanol co-solvent at 25*C can be mathematically described by the Stokes Equation
    • A. 

      True

    • B. 

      False

  • 83. 
    Glycerin and propylene glycol are both miscible with water and ethanol at room temperature
    • A. 

      True

    • B. 

      False

  • 84. 
    Peppermint Water USP is a clear alcoholic solution saturated with volatile peppermint oil and is used as a flavoring agent
    • A. 

      True

    • B. 

      False

  • 85. 
    Particles administered nasally are cleared very slowly, usually within about 300 to 360 minutes by mucociliary transport
    • A. 

      True

    • B. 

      False

  • 86. 
    One of the disadvantages of dry powder inhalers is the dependence of dose delivery on patient inspiratory flow rates
    • A. 

      True

    • B. 

      False

  • 87. 
    The Turbuhaler is a dry powder inhaler that is a multi-dose reservoir device. Reservoir devices use metering mechanisms located inside the device, and this allows many doses to be packaged compactly but they require improved moisture protection and have more dosing variability
    • A. 

      True

    • B. 

      False

  • 88. 
    Petrolatum and Yellow Ointment are examples of hydrocarbon ointment bases used in pharmaceutical compounding
    • A. 

      True

    • B. 

      False

  • 89. 
    Active dry powder inhalers rely solely on the inspiratory effort of the patient to generate the energy for powder entrainment and aerosolization
    • A. 

      True

    • B. 

      False

  • 90. 
    Methy paraben is more stable at pH 5.5 than at 9.0
    • A. 

      True

    • B. 

      False

  • 91. 
    Thermogravimetric analysis (TGA) is an excellent analytical method to determine if a compound is in the dihydrate form or the anhydrous form
    • A. 

      True

    • B. 

      False

  • 92. 
    Physico-chemical properties of a drug include the aqueous solubility, drug stability and its pKa
    • A. 

      True

    • B. 

      False

  • 93. 
    Insoluble polymers are present in latex and pseudolatex colloidal dispersions used to coat tablets and pellets
    • A. 

      True

    • B. 

      False

  • 94. 
    A pharmacist who wishes to open a "Compounding Pharmacy" must obtain an additional license from the State Board of Pharmacy before he/she can operate such a pharmacy
    • A. 

      True

    • B. 

      False

  • 95. 
    Absorption ointment bases, such as Hydrophilic Petrolatum, are anhydrous and not soluble in water, but can absorb water to form an emulsion
    • A. 

      True

    • B. 

      False

  • 96. 
    Oleaginous ointment bases, such as White Petrolatum USP, contain water but do not absorb water readily
    • A. 

      True

    • B. 

      False

  • 97. 
    Fick's 1st law of diffusion describes the passive diffusion process for percutaneous absorption; in other words, it describes the relationship where flux of a diffusing drug is proportional to concentration gradient
    • A. 

      True

    • B. 

      False

  • 98. 
    Aquaphor, which contains cholesterol, lanolin, and white petrolatum, can be added to an oleaginous ointment base to help form an emulsion; and Aquaphor is able to carry up to about 3x its weight in wate
    • A. 

      True

    • B. 

      False

  • 99. 
    Gels are semi-solid colloidal systems in which the movement of the dispersion medium is restricted by an interlacing network of solvated particles
    • A. 

      True

    • B. 

      False

  • 100. 
    Carbopol polymers used to prepare an aqueous gel must be neutralized in order to achieve maximum viscosity; and an example of a water soluble neutralizing agent suitable for neutralizing Carbopol polymeres is trieathanolamine
    • A. 

      True

    • B. 

      False

  • 101. 
    The bioavailability of fentanyl citrate delivered from Actiq is greater than the bioavailability of fentanyl citrate administered orally to the GI tract because buccal delivery bypasses first pass metabolism
    • A. 

      True

    • B. 

      False

  • 102. 
    In the dog study discussed in lecture, referred to as the Streisand Study, it was found that the nonionized fraction of fentanyl citrate that was absorbed buccally increased with increasing pH; and Fentora and Actiq are both buccal drug delivery systems for delivery of fentanyl citrate.
    • A. 

      True

    • B. 

      False

  • 103. 
    Mucoadhesive agents, such as hydroxypropyl methylcellulose and sodium alginate, are used in aqueous nasal spray formulations in order to increase nasal clearance of drug from the nasal passageways
    • A. 

      True

    • B. 

      False

  • 104. 
    A major impediment to pulmonary aerosol delivery is the pharyngeal barrier; and advising the patient to slowly inhale from a spacer device used with a pMDI can partially eliminate the pharyngeal barrier
    • A. 

      True

    • B. 

      False

  • 105. 
    Evaporative loss due to evaporation of liquid solvent from a nebulizer is more significant for air-jet nebulizers, whereas this is not a concern for ultrasonic nebulizers; and the Pari LC Plus air-jet nebulizer uses an open vent system that is inefficient at delivering the dose of the drug to the patient with more waste
    • A. 

      True

    • B. 

      False

  • 106. 
    Nebulizer formulations typically contain a drug dissolved or suspended in a liquid carrier (e.g., purified water) containing an osmotic agent (e.g., sodium chloride) and a buffering agent (e.g., citrate buffer)
    • A. 

      True

    • B. 

      False

  • 107. 
    The Halolite nebulizer provided teh first generation adaptive aerosol delivery, or AAD, in which dosing is better coordinated with the patient's inhalation such that the inhaled medication has the best opportunity to reach deep into the lungs.
    • A. 

      True

    • B. 

      False

  • 108. 
    Passive dry powder inhaler devices rely on the patient to provide energy for entrainment of particles during inhalation of the dose; and the most common type of dry powder inhaler formulation is drug carried onto lactose particles
    • A. 

      True

    • B. 

      False

  • 109. 
    The Diskhaler, an example of a pressurized metered dose inhaler device, employs the propellant HFA 134a as the high vapor pressure propellant
    • A. 

      True

    • B. 

      False

  • 110. 
    Carbopol, carnuba wax, and hydroxypropyl cellulose are all hydrophilic materials that swell in the GI tract to release drug from matrix tablets over an extended period of time
    • A. 

      True

    • B. 

      False

  • 111. 
    Myocet is a liposomal drug delivery system containing doxorubicin citrate and is used to treat various types of cancer
    • A. 

      True

    • B. 

      False

  • 112. 
    HPMCAS is the enteric polymer used on both Strattera and Cymbalta
    • A. 

      True

    • B. 

      False

  • 113. 
    Ethylcellulose is an enteric polymer and begins to dissolve in the GI tract at pH 5.5
    • A. 

      True

    • B. 

      False

  • 114. 
    Film coating s have been used to mask the taste of drugs, to improve drug stability and also to control the release rate of the drug from pellets and tablets
    • A. 

      True

    • B. 

      False

  • 115. 
    Engeric polymers have now been used to prepare liposomes which will dissolve slowly in the bloodstream to target drug delivery to the lung
    • A. 

      True

    • B. 

      False

  • 116. 
    Soybean oil has been used in intravenous fat emulsions to treat comatosed patients and patients suffering from anorexia
    • A. 

      True

    • B. 

      False

  • 117. 
    The organoleptic properties of a New Chemical Entity include both the solubility and stability of that particular compound
    • A. 

      True

    • B. 

      False

  • 118. 
    The ICH guidlines for stability testing of a new pharmaceutical product require accelerated testing to be conducted at 40*C and 75% RH for a minimum of two years
    • A. 

      True

    • B. 

      False

  • 119. 
    Drugs are typically more stable in aqueous solution than when stored in the dry state
    • A. 

      True

    • B. 

      False

  • 120. 
    Preformulation testing enables companies to develop robust formulations by determining the fundamental physical and chemical properties of the NCE prior to designing the formulation for that dosage form
    • A. 

      True

    • B. 

      False

  • 121. 
    For drugs such as ampicillin, the anhydrous form is more soluble and has a faster rate of dissolution and is more bioavailable than the trihydrate form of this compound
    • A. 

      True

    • B. 

      False

  • 122. 
    Formulation challenges with poorly water soluble compounds include:
    • A. 

      Poor or slow dissolution rates

    • B. 

      Low and variable bioavailability

    • C. 

      Difficulty in developing parenteral formulations

    • D. 

      Inability to deliver high doses for toxicity studies

    • E. 

      None of the above

  • 123. 
    Select the one correct answer
    • A. 

      Glycolic acid is a biodegradable polymer

    • B. 

      Diprivan (propofol) is an intravenous emulsion product

    • C. 

      It is important during the film coating of tablets for the tablet to have a low friability. The maximum friability for tablets that are being film coated is approximately 5%

    • D. 

      Lacrisert is a drug delivery device used to decrease tear flow in patients from either an eye infection or glaucoma

    • E. 

      With the recent surge in drug shortages, more than 15% of all prescriptions are now being compounded by registered pharmacists

  • 124. 
    Thermogravemetric analysis (TGA) is a very useful analytical method to predict the solubility of drugs in GI fluid
    • A. 

      True

    • B. 

      False

  • 125. 
    Protein and peptide drugs are more stable at room temperature than in a refrigerator at 5*C
    • A. 

      True

    • B. 

      False

  • 126. 
    Amorphous forms of a compound are typically more solube and have a faster dissolution rate than crystalline forms
    • A. 

      True

    • B. 

      False

  • 127. 
    Acrylic polymers appear to be more stable than polyvinyl acetate, phthalate (PVAP) and cellulose acetate phthalate (CAP), due to hydrolysis of functional groups in PVAP and CAP
    • A. 

      True

    • B. 

      False

  • 128. 
    Aquatcoat consists of pseudolatex of an enteric polymer
    • A. 

      True

    • B. 

      False