Anticoagulants (Exam Mode) By Rnpedia.Com

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Anticoagulants (Exam Mode) By Rnpedia.Com - Quiz

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Questions and Answers
  • 1. 
    Anticoagulants are indicated for an indefinite period in patients with:  
    • A. 

      Atrial fibrillation

    • B. 

      Venous thromboembolism

    • C. 

      High risk of myocardial infarction

    • D. 

      All of the above

  • 2. 
    Which of the following sentence is true with regard to warfarin?
    • A. 

      Is a vitamin K antagonist

    • B. 

      Is a thrombin inhibitor

    • C. 

      Activates fibrinolysis

    • D. 

      Binds to antithrombin III

  • 3. 
    Which of the following is not an approved indication for warfarin therapy?  
    • A. 

      Atrial fibrillation

    • B. 

      Heart valve replacement

    • C. 

      Deep vein thrombosis

    • D. 

      Peripheral artery disease

  • 4. 
    Time taken for observable anticoagulant effect of warfarin is:
    • A. 

      6-12 hours

    • B. 

      24-36 hours

    • C. 

      2-7 days

    • D. 

      8-10days

  • 5. 
    Which of the following is the recommended test to monitor the effect of oral anticoagulant therapy?
    • A. 

      Thrombin time

    • B. 

      International normalized ratio (INR)

    • C. 

      Bleeding time

    • D. 

      Partial thromboplastin time (PTT)

  • 6. 
    What is the most acceptable frequency of INR monitoring in a patient taking warfarin?  
    • A. 

      Initially thrice daily, then twice daily, then daily, then weekly, and then monthly

    • B. 

      Initially twice daily, then daily, then weekly, and then monthly

    • C. 

      Initially daily, then weekly, and then monthly

    • D. 

      Initially twice per week, then weekly, then every two or three weeks, and then monthly

  • 7. 
    What is the value of International normalized ratio (INR) above which warfarin does not provide any additional therapeutic benefit in most patients, but is associated with a higher risk of bleeding?  
    • A. 

      4.0

    • B. 

      3.5

    • C. 

      3.0

    • D. 

      2.5

  • 8. 
     Which of the following is used for reversal of anticoagulant effect of warfarin in case of life-threatening bleeding?  
    • A. 

      Platelets

    • B. 

      Protamine

    • C. 

      Vitamin K or Vitamin K dependant coagulation factors

    • D. 

      Any of the above

  • 9. 
    Which of the following statement(s) concerning heparin is/are true?  
    • A. 

      It binds to antithrombin III leading to anticoagulant effect

    • B. 

      It exhibits varying anticoagulant response

    • C. 

      Heparin therapy is monitored with activated partial thromboplastin time (APTT)

    • D. 

      All of the above

  • 10. 
    Which of the following is an advantage of low molecular weight heparin (LMWH) over unfractionated heparin?  
    • A. 

      Does not require monitoring of activated partial thromboplastin time

    • B. 

      Has a greater bioavailibility

    • C. 

      Given subcutaneously therefore can be administered in “out of hospital setting”

    • D. 

      All of the above

  • 11. 
    Low molecular weight heparins (LMWHs) do not require monitoring, but when necessary, which of the following is measured?  
    • A. 

      Anti-factor Xa level

    • B. 

      Thrombin time

    • C. 

      Prothrombin time

    • D. 

      Activated partial thromboplastin time (APTT)

  • 12. 
    The anticoagulant effect of heparin is rapidly reversed with:
    • A. 

      Protamine

    • B. 

      Infusion of vitamin K dependant coagulation factors

    • C. 

      Packed red blood cells

    • D. 

      Platelets

  • 13. 
    Which of the following anticoagulant should not be given during pregnancy?  
    • A. 

      Warfarin

    • B. 

      Low molecular weight heparins (LMWHs)

    • C. 

      Unfractionated heparin

    • D. 

      All of the above

  • 14. 
    Which of the following is correct with regard to patients taking warfarin undergoing surgery with minimal risk of bleeding?  
    • A. 

      Do not stop warfarin but check INR prior to surgery

    • B. 

      Switch over to heparin two days prior to surgery and restart warfarin after surgery

    • C. 

      Switch over to heparin five days prior to surgery and restart warfarin after surgery

    • D. 

      Switch over to heparin seven days prior to surgery and restart warfarin after surgery

  • 15. 
    Anticoagulation in warfarin users at high risk of thromboembolism, undergoing surgery associated with high risk of bleeding involves: 
    • A. 

      Stop warfarin 4-5 days prior to surgery

    • B. 

      Start with full dose unfractionated heparin or LMWH 2-3 days preoperatively

    • C. 

      Restart regular warfarin therapy after surgery once adequate haemostasis is achieved

    • D. 

      All of the above

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