1.
A nurse is caring for a postsurgical patient who has small tortuous veins and had a difficult IV insertion The patient is now receiving IV medications on a regular basis What is the best nursing intervention to minimize the adverse effects of this drug therapy?
A. 
Monitor the patient's bleeding time
B. 
Check the patient's blood glucose levels
C. 
Record baseline vital signs
D. 
Monitor the IV site for redness, swelling, or pain
2.
A patient is in the clinic after 6 weeks of taking riluzole (Rilutek) for a recent diagnosis of amyotrophic lateral sclerosis The nurse will prioritize assessment for which of the following?
A. 
B. 
C. 
D. 
3.
Which of the following patients demonstrates the clearest indication for treatment with prednisone?
A. 
A 66-year-old woman whose history of smoking has culminated in a diagnosis of emphysema
B. 
A 70-year-old man whose rheumatoid arthritis has not responded to OTC pain relievers
C. 
A 12-year-old boy whose long-standing fatigue and malaise have been attributed to leukemia
D. 
A 50-year-old woman who is being treated for hypertension with a diuretic and an ACE inhibitor
4.
A nurse has been administering a drug to a patient intramuscularly (IM). The physician discontinued the IM dose and wrote an order for the drug to be given orally. The nurse notices that the oral dosage is considerably higher than the parenteral dose and understands that this due to:
A. 
B. 
C. 
D. 
5.
A cardiac care nurse is monitoring a patient who is receiving lidocaine (Xylocaine) per IV infusion pump for an acute ventricular arrhythmia associated with an acute MI. Which of the following patient manifestations would cause the nurse to notify the physician immediately?
A. 
B. 
C. 
D. 
6.
A nurse is caring for a patient who is admitted into the cardiac care unit with acute, decompensated heart failure. Nesiritide (Natrecor) has been ordered. When preparing for administration of the drug, the nurse will:
A. 
Add the reconstituted vial of medication to a 1,000 mL IV bag
B. 
Shake the vial vigorously to mix the medication for reconstitution
C. 
Administer the initial IV bolus over approximately 60 seconds
D. 
Use the reconstituted solution within a 36-hour period
7.
A patient has been prescribed lithium therapy. Which of the following signs and symptoms will the nurse tell the patient to report immediately?
A. 
B. 
C. 
D. 
8.
A nurse is caring for a patient who has just been diagnosed with Parkinson disease. The patient does not understand how the medication ordered, carbidopa-levodopa, is going to help her condition. Which of the following is the correct response by the nurse?
A. 
“Carbidopa-levodopa will delay the loss of muscle strength and limb function for several months”
B. 
“This drug will change the immune processes in your body to help decrease the tissue damage”
C. 
“Carbidopa-levodopa increases the activity of dopamine in your body, which will decrease your symptoms”
D. 
“Your drug therapy will reduce excessive reflex activity causing your muscle spasms and will allow for muscle relaxation”
9.
A patient is taking flavoxate hydrochloride (Urispas) to help control an overactive bladder. On a follow-up visit to the clinic, the nurse will question the patient about which of the following?
A. 
B. 
C. 
D. 
10.
A nurse notes new drug orders for a patient who is already getting several medications. Which of the following is the most important consideration when preparing to administer the new drugs?
A. 
How the patient will feel about new medications added to her drug therapy
B. 
Possible drug–drug interactions that might occur
C. 
Any special nursing considerations that the nurse must be aware of
D. 
If generic preparations of the drugs can be used
11.
A nurse is discussing with a patient the efficacy of a drug that his physician has suggested, and he began taking. Efficacy of a drug means which of the following?
A. 
The amount of the drug that must be given to produce a particular response
B. 
How well a drug produces its desired effect
C. 
A drug's strength of attraction for a receptor site
D. 
A drug's ability to stimulate its receptor
12.
A nurse is conducting a medication resolution of a new resident of a care facility and notes that the woman has been taking neostigmine. The nurse should recognize that the woman may have a history of what health problem?
A. 
B. 
C. 
D. 
13.
A 77-year-old man's chronic heart failure is being treated with a regimen of quinapril (Accupril) and furosemide (Lasix). Which of the following assessment findings would suggest that the loop diuretic is contributing to a therapeutic effect?
A. 
The man's glomerular filtration rate and creatinine levels are within reference ranges
B. 
The man's heart rate is between 60 and 70 beats per minute with a regular rhythm
C. 
The man's potassium and sodium levels remain with reference ranges
D. 
The man's chest sounds are clear and his ankle edema is lessened
14.
A nurse explains to a patient that nitroglycerin patches should be applied in the morning and removed in the evening. This medication schedule reduces the potential for:
A. 
B. 
C. 
D. 
15.
A nurse who provides care on a busy medical unit of a large hospital is constantly faced with new drugs on patients' medication administration records. What strategy should the nurse employ to foster up-to-date information about the nursing management of new or uncommon drugs?
A. 
Focus on learning about a prototype drug that is characteristic of a larger drug class
B. 
Identify similarities between new drugs and older drugs that are commonly used on the unit
C. 
Commit time and energy during each shift to learning about new drugs
D. 
Liaise with pharmacists and pharmacy technicians who work at the hospital
16.
A 58-year-old man is admitted to the emergency department. A diagnosis of severe digoxin toxicity is made. Bradycardia is present, and an electrocardiogram (ECG) confirms toxicity. The nurse will administer which of the following drugs?
A. 
B. 
C. 
D. 
17.
A hospital patient's physician has prescribed quetiapine (Seroquel) to be administered at bedtime. Being unfamiliar with the medication, the nurse has looked it up in a nursing drug manual and noted that the drug is an antipsychotic that is indicated for the treatment of schizophrenia and bipolar disorder. The patient has no psychiatric history, and upon questioning, the physician states that it is being prescribed to help the patient fall asleep at night. How should the nurse best understand this practice?
A. 
This off-label use of the drug is prohibited by federal laws and professional practice standards
B. 
This is an appropriate use of the drug, provided it is supported by the literature
C. 
This is acceptable if the patient has failed to respond adequately to conventional sleep aids
D. 
This is a practice that may negate the physician's and nurse's liability insurance
18.
A 4-year-old child is brought to the emergency department by her mother. The mother reports that the child has been vomiting, and the nurse notes that the child's face is flushed and she is diaphoretic. The mother thinks that the child may have swallowed carbachol drops. A diagnosis of cholinergic poisoning is made. Which of the following drugs would be administered?
A. 
B. 
C. 
D. 
19.
A nurse is providing discharge instructions to a patient who will be taking fludrocortisone at home. The nurse will encourage the patient to eat a diet that is:
A. 
Low in sodium and potassium
B. 
Low in sodium, high in potassium
C. 
D. 
20.
A nurse is developing a care plan for a patient who has multiple sclerosis. An expected outcome for the patient who is receiving glatiramer would be a decrease in:
A. 
B. 
C. 
D. 
21.
An elderly postsurgical patient has developed postoperative pneumonia in the days following abdominal surgery and is being treated with a number of medications. Which of the following medications that the nurse will administer has the slowest absorption?
A. 
A sublingual benzodiazepine that has been prescribed to help the patient sleep
B. 
An intravenous (IV) antibiotic that is being administered by IV piggyback at 150 mL/hour
C. 
An oral antidepressant that the patient has been taking daily for several years
D. 
An intramuscular (IM) injection of an opioid analgesic
22.
A female patient diagnosed with chronic atrial flutter has been prescribed verapamil in conjunction with digoxin to control ventricular rate. To enhance the therapeutic effect of the drug, the nurse will instruct the patient to:
A. 
Take the medication with meals
B. 
Avoid grapefruit and grapefruit juice
C. 
Take an aspirin every day
D. 
23.
A 28-year-old patient asks his nurse how phenelzine therapy would help him. An appropriate response by the nurse would be:
A. 
“This therapy will help reduce the severity of your bipolar episodes”
B. 
“The drug will enable you to gain the appropriate weight”
C. 
“The drug will help increase your attention level”
D. 
“This therapy will improve your overall mood and increase your social activity”
24.
A nurse is creating a plan of care for a 68-year-old woman with a recent diagnosis of unstable angina and new prescription for nitroglycerin. Which of the following nursing diagnoses should the nurse prioritize in the planning of this patient's care?
A. 
Incontinence, Functional, related to adverse effects of drug therapy
B. 
Risk for Fluid Volume Deficit related to adverse effects of drug therapy
C. 
Confusion, Acute, related to adverse effects of drug therapy
D. 
Acute Pain, Headache, related to adverse effects of drug therapy
25.
A nurse is caring for a 38-year-old female patient who just started taking lithium for bipolar disorder. Which of the following outcomes would be most appropriate for this patient?
A. 
The patient will reestablish and maintain a normal pattern of bowel functioning
B. 
The patient will identify appropriate interventions to promote sleep
C. 
The patient will identify satisfying and acceptable sexual practices and some alternative ways of dealing with sexual expression
D. 
The patient will adopt strategies to maintain proper fluid balance