1.
Edrophonium chloride inhibits the breakdown of _____ at the postsynaptic membrane.
2.
Base on what is known about myasthenia gravis, nerve impulses from motor neuromuscular junctions are unable to fully stimulate the affected muscle.
3.
This patient has the classical signs, symptoms, and laboratory data to determine a diagnosis of Muscular dystrophy.
4.
This patient has the classical signs, symptoms, and laboratory data to determine a diagnosis of myasthenia gravis.
5.
Edrophonium chloride should increase muscle excitation and contractio. The other responses are undesirable in myasthenia gravis and are likely physical effects of this drug.
6.
Which symptom(s) was/were not found in your patient's examination?
A.
Food felt like it was sticking in her throat
B.
C.
Difficulty combing her hair
D.
She has a very happy marriage
E.
7.
Dr. Zoe Boutella was admitted into the hospital for which medical conditions?
A.
B.
Velopharyngeal insufficiency
C.
Limited facial expressions
D.
Difficulty swallowing (dysphagia)
E.
Drooping of both eyelids (ptosis)
8.
Zoe Boutella had recently experienced an extremely stressful divorce.
9.
Upon physical examination, Dr. Zoe Boutella was unable to close both of her eyes completely.
10.
Upon physical examination of Dr. Boutella, only her left pupil respond normally to light and show normal accommodation.
11.
Upon physical examination of Zoe's past medical history, she lost ___ kilograms in the past month.
12.
Zoe Boutella's laboratory results indicated a positive antibody test which is indicative of a(n)_____?
A.
Autoimmune disorder attacking muscle cells
B.
Autoimmune disorder attacking heart muscle cells
C.
Autoimmune disorder attacking smooth muscle cells
D.
Autoimmune disorder support healthy muscle cells
13.
Dr. Colin Quinto, used a pharmacological test using edrophonium chloride on his patient, Dr. Zoe Boutella a genetics researcher.
14.
Base on what is known about myasthenia gravis, adenosine triphosphate pulls the thick myofilaments during muscle contraction.
15.
Based on the action of edrophonium chloride, as stated in the case study. How will this drug work in Dr. Zoe Boutella's case?
A.
Increases the availability of acetycholine at postsynaptic receptor sites.
B.
Decreases availability of acetycholine at the postsynaptic receptor sites.
C.
Increases attachment of thick myosin filaments to the sarcomere.
D.
Decreases electrical impulses in the sarcolemma
16.
Base on side effects of edrophonium chloride, which of the following physical effects will most likely be noted by Dr. Boutella?
A.
Spasm of accomodation (adjustment of focus)
B.
Decreased muscle excitation & contraction
C.
Increased muscle excitation & contraction
D.
17.
Based on the information presented in the case study, Dr. Zoe Boutella has Poliomyelitis.
18.
Based on the information presented in the case study, Dr. Zoe Boutella has fibromyositis.
19.
Based on the information presented in the case study, Dr. Boutella has myasthenia gravis.
20.
Upon physical examination of Dr. Boutella, Dr. Quinto performed an Ice Cube Test on the right eyelid only.
21.
What occupation did Zoe's parents, Dr. Karl and Dr. Martha Boutella do?
A.
B.
C.
D.
Surgeons at Mountaineer Medical Center
E.
Military Science Researchers
22.
___-___ ___ is a receptor tyrosine kinase required for the formation and maintenance of the neuromuscular junction. It is activated by a nerve-derived proteoglycan called agrin.
23.
In patients with myasthenia gravis, your immune system produces antibodies that block or destroy many of your muscles' receptor sites for a neurotransmitter called ___.
24.
Which one of Dr. Zoe Boutella's physicians conducted a Nerve Conduction and Nerve Conduction Velocity Study?
25.
Select the tests conducted on Dr. Zoe Boutella that were negative.
A.
B.
Thoracic X-Rays showed widened mediastinum
C.
D.
Congenital Myasthenic syndrome
E.
Muscle-Specific Kinase is present
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