1.
Site of RBC formation in 20 year old healthy male is:
Correct Answer
A. Flat bones
Explanation
In adults, the bone marrow in the flat bones is actively involved in RBC production.
2.
Which of the following is true about fourth heart sound ‘S4‘ :
Correct Answer
C. Heard during ventricular filling phase
Explanation
S4 is heard during the last rapid filling phase of cardiac cycle.
3.
Broca’s area is concerned with:
Correct Answer
A. Word formation
Explanation
Broca's area is the motor speech area concerned with word formation.
4.
The mechanism of hearing and memory, include all except:
Correct Answer
C. Recruitment by multiplication of neurons
Explanation
There is no multiplication of neurons in memory formation.
5.
The processing of short term memory to long term memory is done in:
Correct Answer
B. Hippocampus
Explanation
Hippocampus is concerned with conversion of short term memory to long term memory.
6.
Delta waves are seen in :
Correct Answer
A. Deep sleep
Explanation
Delta waves are seen in Deep sleep. [Remember as D(delta) with D(deep sleep). ]
7.
Toxic effects of high oxygen tension include all of the following except:
Correct Answer
B. Decreased cerebral blood flow
Explanation
Decreased cerebral blood flow is not described as a complication of high oxygen tension.
8.
Which of the following adaptations will be apt to increase the work capacity at high altitude?
Correct Answer
C. Decreasing workload, increasing duration of exercise
Explanation
In high altitude, the oxygen availability is low. Hence the work that can be done per unit time is low. This can be compensated by decreasing the rate of doing work and increasing the duration of work.
9.
All of the following statements are true for ‘Intestinal Motility’ except:
Correct Answer
A. Does not depend on Gastric motility
Explanation
Intestinal motility is influenced by gastric motility. eg: Migratory motor complex, gastroileal reflex
10.
Which of the following hormone is not secreted by the kidney:
Correct Answer
B. Angiotensin I
Explanation
Angiotensin I is formed by action of Renin (secreted by kidney) on Angiotensinogen (secreted by liver).
11.
Chronic carrier state is seen in all except
Correct Answer
A. Measles
Explanation
Measles has no chronic carrier state.
12.
Least common complication of measles is
Correct Answer
A. SSPE
Explanation
SSPE (Sub acute sclerosing panencephalitis) is the least common complication of measles. It is also the most severe.
13.
Under eradication of congenital rubella syndrome program the first priority group for rubella vaccination is
Correct Answer
A. All non pregnant women of age 15 to 34
Explanation
First priority - Women of child bearing age ( All non pregnant women of age 15 to 34 )
Second priority - Children of 1-14 years of age
Third priority - Children at 1 year of age
14.
Strategies for prevention of Neonatal Tetanus include all of the following except:
Correct Answer
B. Giving penicillin to all the new borns
Explanation
Giving penicillin to all the new borns is not recommended for prevention of neonatal tetanus.
15.
Which is true of BCG vaccination ?
Correct Answer
D. WHO recommends Danish 1331 strain for vaccine production
Explanation
Normal saline is used as a diluent. Site of injection should be cleaned with normal saline. Mantoux test becomes positive after 8 weeks.
16.
Case finding in RNTCP is based on
Correct Answer
B. Sputum microscopy
Explanation
Patients presenting with symptoms of tuberculosis are screened by sputum smear examination.
17.
Which of the following statements about lepromin test is not true
Correct Answer
B. It is a diagnostic test
Explanation
Lepromin test is not diagnostic of leprosy.
18.
Which of the following is not transmitted by lice,
Correct Answer
A. Q fever
Explanation
Q fever is transmitted by soft ticks.
19.
True about endemic typhus —
Correct Answer
B. Flea is a vector of the disease
Explanation
Rats are also reservoirs of infection. Eschar is seen in scrub typhus. Serological tests are used for diagnosis.
20.
On SAFE strategy false is
Correct Answer
A. Screening
Explanation
Components of safe strategy:
S - Surgery
A - Antibiotics
F - Facial hygiene
E - Environmental modification
21.
Bohler’s angle is decreased in fracture of
Correct Answer
A. Calcaneum
Explanation
Bohler’s angle is formed at the junction of:
-line joining the posterosuperior part of the calcaneal tuberosity and the uppermost point on the posterior articular surface for talus
-line joining the uppermost point on the posterior articular surface for talus and the anterior process of the calcaneum
Normal value is 25-40°. It is decreased in fracture of calcaneum. (usually occurs in fall from height)
22.
Which is not a deep heat therapy
Correct Answer
C. Infrared therapy
Explanation
Infrared therapy is a type of superficial heat therapy.
23.
Most common site of osteosarcoma is
Correct Answer
B. Lower end of femur
Explanation
Osteosarcoma is a type of bone cancer that commonly occurs in the long bones of the body. It is most frequently found in the lower end of the femur, which is the thigh bone. This area is susceptible to osteosarcoma due to its high growth rate during adolescence and the presence of a growth plate. Osteosarcoma can also occur in other bones such as the tibia and humerus, but the lower end of the femur is the most common site for this type of cancer.
24.
About congenital torticollis all are true except :
Correct Answer
A. Always associated with breech extraction
Explanation
Congenital torticollis is most commonly associated with breech extraction. But not always.
25.
Rickets in infancy is characterised by the following except :
Correct Answer
D. Bow legs
Explanation
Bow legs appear only after the child starts walking - due to weight bearing effect.
26.
In patients with osteoarthritis of knee joint, atrophy occurs most commonly in which muscle :
Correct Answer
A. Quadriceps only
Explanation
Quadriceps is the most commonly affected muscle is osteoarthritis of knee.
27.
60 yrs old male with bony abnormality at upper tibia associated with sensorineural hearing loss. On laboratory examination serum alkaline phosphatase levels are (440 mU/l) elevated and serum Ca and PO4 are normal. Skeletal survey shows ivory vertebrae and cotton wool spots in x-ray skull. Diagnosis is :
Correct Answer
B. Paget disease
Explanation
The age, clinical features and investigation findings are characteristic of Paget's disease.
28.
Meralgia paresthetica is due to involvement of
Correct Answer
B. Lateral cutaneous nerve of thigh
Explanation
Meralgia paresthetica is characterised by pain, tingling and numbness in lateral aspect of thigh. There is no motor deficiency. It is due to involvement of lateral cutaneous nerve of thigh.
29.
Pigmented villouodular synovitis most commonly affects :
Correct Answer
C. Knee
Explanation
It is a benign condition characterised by exuberant proliferation of synovial tissue. It affects synovial joints, tendon sheaths and bursae.
30.
Following are associated with CV junction anomalies except -
Correct Answer
D. None of the above
Explanation
All of the above are associated with craniovertebral junction anomalies.
31.
All the following statements are true about V. cholera 0139 except:
Correct Answer
D. Produces O1 Lipopolysaccharide
Explanation
V. cholera 0139 does not synthesise O1 Lipopolysaccharide
32.
An elderly male patient presented with fever, chest pain and dry cough. Sputum culture showed growth on Charcol Yeast Extract Medium. The organism is
Correct Answer
C. Legionella
Explanation
Legionella grows only in special media like Charcol Yeast Extract Medium
33.
A person working in an abattoir presented with a papule on hand, which turned into an ulcer. Which will best help in diagnosis?
Correct Answer
A. Trichrome Methylene Blue
Explanation
The clinical features are suggestive of cutaneous anthrax. Trichrome methylene blue is used to demonstrate McFadyean's reaction which is characteristic of Bacillus anthracis.
34.
Brucella is transmitted by all expect:
Correct Answer
C. Person to person
Explanation
There is no person to person transmission in brucella.
35.
Botulisum affects all except:
Correct Answer
D. CNS
Explanation
CNS is not involved in botulism.
36.
With reference to bacteriodes fragilis, the following statements are true except:
Correct Answer
D. Shock and DIC are common in bacteroides bacteremia
Explanation
Shock and DIC are not common in bacteroides bacteremia.
37.
Which of the following statement is not true regarding Chlamydia Trachomatis:
Correct Answer
A. Elementary body is metabolically active
Explanation
Reticulate body is metabolically active.
38.
Rabies is identified by
Correct Answer
B. Negri bodies
Explanation
Guarneri bodies - Vaccinia
Negri bodies - Rabies
Cowdry A bodies - Herpes / yellow fever
Cowdry B bodies - Adenovirus / pollovirus
39.
All statements are true for Chylamydia psittacosis except:
Correct Answer
B. Causes urethritis
Explanation
Chlamydia psittacosis is a bacterial infection that is acquired from bird's droppings. It causes pneumonia and can be treated with tetracycline. However, it does not cause urethritis, which is inflammation of the urethra.
40.
Only hepatitis virus which can be cultured is
Correct Answer
A. HAV
Explanation
HAV is the only hepatitis virus that can be cultured.
41.
Reticulocytosis is seen in all except :
Correct Answer
C. Nutritional anemia
Explanation
Reticulocytosis is the increased presence of reticulocytes, which are immature red blood cells, in the bloodstream. It is a normal response to conditions that cause increased red blood cell destruction or decreased red blood cell production. P.N.H. (paroxysmal nocturnal hemoglobinuria), hemolysis, and dyserythropoietic syndrome are all conditions that can result in increased red blood cell destruction or decreased red blood cell production, leading to reticulocytosis. However, nutritional anemia, which is caused by deficiencies in essential nutrients like iron, vitamin B12, or folate, does not typically cause reticulocytosis.
42.
Which of the following dietary interventions reduces the further risk in MI patients-
Correct Answer
D. N3 polyunsaturated fatty acids
Explanation
n3 polyunsaturated fatty acids, such as omega-3 fatty acids, have been shown to have numerous cardiovascular benefits, including reducing the risk of further cardiovascular events in patients with myocardial infarction (MI). These fatty acids have anti-inflammatory and anti-thrombotic effects, which can help prevent the progression of atherosclerosis and reduce the risk of future heart attacks. They also have positive effects on lipid profiles, reducing triglyceride levels and increasing HDL cholesterol levels. Therefore, incorporating n3 polyunsaturated fatty acids into the diet can be an effective dietary intervention for reducing the further risk in MI patients.
43.
Addison’s disease is associated with all except
Correct Answer
D. Low renin levels
Explanation
Addison's disease is a condition characterized by the insufficient production of adrenal hormones, particularly cortisol. One of the primary functions of cortisol is to regulate blood pressure by increasing the sensitivity of blood vessels to constricting signals from the hormone aldosterone, which is regulated by renin. Therefore, in Addison's disease, where cortisol production is reduced, renin levels would be expected to be high rather than low. Thus, low renin levels are not associated with Addison's disease.
44.
All are associated with MEN-2 except :
Correct Answer
B. Lslet cell hyperplasia
Explanation
MEN-2 (Multiple Endocrine Neoplasia Type 2) is a genetic disorder characterized by the development of tumors in various endocrine glands. Pheochromocytoma, medullary carcinoma of the thyroid, and parathyroid adenoma are all associated with MEN-2. However, lslet cell hyperplasia is not typically associated with MEN-2. Therefore, the correct answer is lslet cell hyperplasia.
45.
Increased anion gap metabolic acidosis is seen in all except :
Correct Answer
D. Diarrhoea
Explanation
Mnemonic for causes of increased anion gap metabolic acidosis: MUDPILES
M-Methanol
U-Uremia (chronic renal failure)
D-Diabetic ketoacidosis
P-Propylene glycol
I-Infection, Iron, Isoniazid
L-Lactic acidosis
E-Ethylene glycol
S-Salicylates, Starvation
46.
Ratio of AST/ALT > 1 present in
Correct Answer
B. Alcoholic hepatitis
Explanation
Alcoholic hepatitis is characterized by inflammation of the liver caused by excessive alcohol consumption. One of the diagnostic markers for alcoholic hepatitis is the ratio of AST (aspartate aminotransferase) to ALT (alanine aminotransferase) in the blood. In alcoholic hepatitis, this ratio is typically greater than 1. Therefore, the correct answer is alcoholic hepatitis.
47.
A female child with virilization, hypertension and low plasma renin. Diagnosis is :
Correct Answer
B. 11 beta hydroxylase deficiency
Explanation
11 beta hydroxylase deficiency is the correct diagnosis in this case. This condition is a form of congenital adrenal hyperplasia (CAH) that affects the enzyme 11 beta hydroxylase, leading to a deficiency in cortisol and aldosterone production. The symptoms of virilization, hypertension, and low plasma renin are characteristic of this condition. In 11 beta hydroxylase deficiency, excess androgens are produced, leading to virilization in females. Hypertension is caused by the accumulation of mineralocorticoids. Low plasma renin is a result of the negative feedback on renin production due to excess mineralocorticoids.
48.
Features seen in hemolytic anemia are all except
Correct Answer
A. Tear drop and Burr cells
Explanation
Hemolytic anemia is characterized by the premature destruction of red blood cells, leading to a decrease in their lifespan. The features commonly seen in hemolytic anemia include decreased haptoglobin (a protein that binds to free hemoglobin), reticulocytosis (an increase in immature red blood cells), and hemoglobinuria (the presence of hemoglobin in the urine). Tear drop and Burr cells, on the other hand, are not typically associated with hemolytic anemia. Tear drop cells are usually seen in myelofibrosis, while Burr cells are commonly observed in conditions like uremia and liver disease.
49.
Nephrocalcinosis is seen in all except :
Correct Answer
D. Medullary cystic kidney
Explanation
Nephrocalcinosis refers to the deposition of calcium in the renal parenchyma, leading to the formation of calcifications. It is commonly associated with various renal disorders. Sarcoidosis, distal renal tubular acidosis (RTA), and milk alkali syndrome are known to be associated with nephrocalcinosis. However, medullary cystic kidney is not typically associated with nephrocalcinosis. Medullary cystic kidney disease is a genetic disorder characterized by the progressive destruction of the renal medulla, leading to renal failure. Although it may present with other renal abnormalities, nephrocalcinosis is not a typical feature of medullary cystic kidney.
50.
Interstitial nephritis is seen with all except :
Correct Answer
B. INH
Explanation
Interstitial nephritis is a condition characterized by inflammation of the spaces between the kidney tubules. It is commonly caused by certain medications. Beta lactam inhibitors, diuretics, and allopurinol are known to be associated with interstitial nephritis. INH, which stands for isoniazid, is a medication used to treat tuberculosis. It is not typically associated with interstitial nephritis, making it the exception in this list.