Trivia Quiz About Biochemistry
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- 1.Which of the following is not true regarding urea cycle
- A.
Main way of excretion of ammonia
- B.
Plasma urea is 15-45 mg/l
- C.
As a result of transamination glutamate combines with acetyl CoA forming N-acetyl glutamate which inhibits CPS I
- D.
2 of the above
- E.
None of the above
- 2.What happens in the synthesis of non-essential glycine
- A.
Serine changes to glycine by serinehydroxymethyltransferase
- B.
H2O is released in the reactionn above
- C.
Can be formed also from glyoxalate by transamination
- D.
In glycine synthase coenzyme NAD+ is reduced to NADH
- E.
All of the above
- 3.Regarding Cysteine which of the following is true
- A.
Formed from serine and homocysteine
- B.
PLP Is needed in the reaction of serine & homocysteine
- C.
Cysteine becomes essential if methionine is adequate
- D.
A+B
- E.
C+A
- 4.What is needed/ happens in the reaction of aspartic acid with asparagine (either way)
- A.
Asparagine synthetase, Gln, Glu, ATP----> AMP + PPi
- B.
Asparagine synthetase, ATP ---> ADP + Pi
- C.
Asparaginase, NH4+, H2O
- D.
Asparaginase lyase, NAD+, ATP ---> AMP + PPi
- E.
asparaginase, NH3, H2O, Gln, Glu
- 5.Which of the following is/are ketogenic and glucogenic amino acid(s)?
- A.
Alanine
- B.
Tryptophan
- C.
Leucine
- D.
Valine
- E.
A+C
- 6.Brain damage from high ammonia concentrations is shown through
- A.
Irritability and tremors
- B.
Blurred vision
- C.
Coma
- D.
Inverted sleep rhythm
- E.
All of the above
- 7.A fatty acid chain with 18 c atoms , the number of ATP that will be produced by complete oxidation on this chain is
- A.
148
- B.
108
- C.
146
- D.
38
- E.
40
- 8.When there is deficiency in hydroxyacyl coa dehydrogenase E the B oxidation will end in which of the following
- A.
2-hydroxy acyl coa
- B.
B-hydroxyacyl coa
- C.
Alpha-hydroxyacyl coa
- D.
1-hydroxyacyl coa
- E.
None of the above
- 9.15c atom fatty acid chain one of these at carbon number 3 of the chain ,the number of ATP that will be produced by complete oxidation of this chain is
- A.
114
- B.
28
- C.
30
- D.
84
- E.
112
- 10.Increase which of the following decreases B oxidation
- A.
AMP
- B.
FAD
- C.
FMN
- D.
Prostaglandins
- E.
None of the above
- 11.50years old male with carnitine deficiency ,which of the following is true regarding his case
- A.
he complains from cerebellar ataxia
- B.
His liver is highly fatty
- C.
Has decreased uptake of glucose by cardiac muscle
- D.
8c atoms fatty acid chain can be oxidized in his liver cells
- E.
More than one of the above
- 12.Alpha carbon in Fatty acid is the
- A.
Carbon of the carboxylic group
- B.
Carbon where phytanic Acid oxidation begins
- C.
Last carbon
- D.
Carbon where CoASH binds
- E.
More than one of the above
- 13.The most important eicosanoids are formed of
- A.
dihomo-γ-linolenic acid
- B.
Arachidonic acid
- C.
Timnodonic acid
- D.
All of the above
- 14.Cyclooxygenase (COX)is responsible for all the following, Except
- A.
the cyclization of C8-C12 of arachidonic acid to form cyclopentane ring
- B.
The presence of endoperoxide between C9 and C11
- C.
Reduction of the hydroperoxyl group at C15 into hydroxyl group
- D.
Introduces a hydroperoxyl group at C15
- 15.All the followings enzymes act on the PGH2, which of them will convert it to PGI2:
- A.
Isomerase
- B.
.Prostacyclin synthase
- C.
Reductase
- D.
Thromboxane reductase
- 16.Inhibits the cyclooxygenase by acetylation
- A.
.hydrocortisone
- B.
Indomethacin
- C.
Aspirin
- D.
Two of the above
- 17.All the followings are the effects of prostaglangins on different tissues,Except
- A.
Increase cAMP in many endocrine glands leading to increased secretion of their hormones
- B.
Decrease cAMP in other tissues leading to decreased gastric HCL
- C.
PGE produces hypertension
- D.
PGF produces (bronchoconstriction)
- 18.All the followings are correct about the Lipoxygenase pathway, Except
- A.
Leukotrienes are early discovered in leukocytes
- B.
Leukotrienes are released during anaphylaxis
- C.
LTE4 comprise the slow-reacting substances of anaphylaxis (SRS-A
- D.
Lipoxins may have a role in regulating the immune response
- E.
None of the above
- 19.L-amino acid oxidase coenzyme is
- A.
FAD
- B.
NAD+
- C.
FMD
- D.
FMN
- 20.Transamination can occur in
- A.
Liver
- B.
Kidney
- C.
Muscles
- D.
All tissues
- 21.The main mechanism for deamination of amino acids is
- A.
Transdeamination
- B.
Transmination
- C.
Oxidative deamination
- D.
Reductive deamination
- 22.H2O2 is produced as a side product in
- A.
Transdeamination
- B.
Transamination
- C.
Oxidative deamination
- D.
Reductive deamination
- 23.Alanine transaminase(ALT) doesn't include
- A.
PLP
- B.
Oxaloacetic acid
- C.
Pyruvic acid
- D.
None of the above
- 24.One of these is not needed to form Glutamine
- A.
ATP
- B.
NH3
- C.
Glutamic acid
- D.
α-ketoglutaric acid
- 25.One of the following is not included in the process of synthesis of FA
- A.
Extramitochondrial system
- B.
Microsomal system
- C.
Peroxisomal system
- D.
Mitochondrial system
- 26.One of the following is considered as a stem fatty acid
- A.
Arachidonic acid
- B.
Phtanic acid
- C.
Adipic acid
- D.
Palmitic acid
- 27.One of the following statements is false
- A.
Fatty acid synthase multi-enzyme complex is in its active form when it is a dimer
- B.
Each monomer contains 2 SH groups the first one is carried by phosphopantetheine and the other one is carried by ketoacyl reductase enzyme.
- C.
Acetyl coA carboxylase requires Mn+2 and biotin
- D.
Thioesterase enzyme is also called deacylase.
- 28.the reaction of transformation of beta ketoacyl enzyme to beta hydroxyacyl enzyme is catalyzed by
- A.
Ketoacetyl reductase
- B.
Enoyl reductase
- C.
Dehydratase
- D.
Ketoacyl reductase
- 29.The enzyme that catalyze the decomposition of citrate in the cytosol to OAA and acetyl-coA is
- A.
ADP citrate synthase
- B.
ADP OAA lyase
- C.
ATP- coA lyase
- D.
ATP - citrate lyase
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