Pharma_cvs_ihd_quiz_dr_aboshousha

5 Questions

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Pharma_cvs_ihd_quiz_dr_aboshousha

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Questions and Answers
  • 1. 
    All these drug groups useful in angina as they directly increase myocardial oxygen delivery  (by  reversing coronary  arterial spasm), EXCEPT: 
    • A. 

      Nitrates and nitrite drugs

    • B. 

      Calcium channel blockers

    • C. 

      Beta-adrenoceptor-blocking drugs

    • D. 

      All the above

  • 2. 
     Which of the following statements concerning nitrate mechanism of action is/are True? 
    • A. 

      Therapeutically active agents in this group are capable of releasing nitric oxide (NO) in to vascular smooth muscle target tissues

    • B. 

      Nitric oxide (NO) is an effective activator of soluble guanylyl cyclase and probably acts mainly through this mechanism

    • C. 

      Nitrates useful in angina decrease myocardial oxygen requirement (by decreasing the determinations of oxygen demand) and increase myocardial oxygen delivery (by reversing coronary arterial spasm)

    • D. 

      All of the above

  • 3. 
    Which of the following nitrates  and nitrite drugs are long-acting? 
    • A. 

      Nitroglycerin, sublingual

    • B. 

      Isosorbide dinitrate, sublingual

    • C. 

      Nitroglycerin, spray

    • D. 

      Isosorbide mononitrate

  • 4. 
    Duration of nitroglycerin action (sublingual) is:  
    • A. 

      10-30 minutes

    • B. 

      6-8 hours

    • C. 

      3-5 minutes

    • D. 

      1.5-2 hours

  • 5. 
    The following statements concerning mechanism of nitrate beneficial clinical effect are true, EXCEPT? 
    • A. 

      Decreased myocardial oxygen requirement

    • B. 

      Relief of coronary artery spasm

    • C. 

      Improved perfusion to ischemic myocardium

    • D. 

      Increased myocardial oxygen consumption