Mock GPAT 4
Graduate Pharmacy Aptitude Test
Each correct answer has 3 points
There is 1 negative point for each incorrect answer.
ALL THE BEST !
- 1.
REQUIREMENTS OF PREMISES, PLANT AND EQUIPMENT FOR PHARMACEUTICAL PRODUCTS : are covered under which schedule of Drug and Cosmetic act?
- A.
Schedule M
- B.
Schedule V
- C.
Schedule N
- D.
Schedule O
Correct Answer
C. Schedule N -
- 2.
Identify an incorrect statement about benzodiazepines:
- A.
Alkyl substituents at 3-position decreases the activity
- B.
The N-substituent at 1-position should be small
- C.
A phenyl or pyridyl at the 5-position decreases the activity
- D.
The presence of electron-attracting substituents at position 7 is required for activity
Correct Answer
C. A phenyl or pyridyl at the 5-position decreases the activity -
- 3.
Which of the following heterocyclic ring system would you expect to be present in Atorvastatin?
- A.
Naphthalele
- B.
Indole
- C.
Pyridine
- D.
Pyrrole
Correct Answer
D. Pyrrole -
- 4.
Glycoprotein laminin functions as :
- A.
Cell recognition and adhesion
- B.
Transporter
- C.
Antigens
- D.
Blood clotting
Correct Answer
A. Cell recognition and adhesion -
- 5.
In Polarography, Half-Wave potential and Diffusion current give:
- A.
Qualitative & Quantitative information respectively
- B.
Both give Qualitative information only
- C.
Quantitative & Qualitative information respectively
- D.
Both give Quantitative information only
Correct Answer
A. Qualitative & Quantitative information respectively -
- 6.
Which of the following is an example of Neurotoxin?
- A.
Tetanus
- B.
Vibrion
- C.
Tubercullin
- D.
Taxol
Correct Answer
A. Tetanus -
- 7.
Minute opening of the tubular structure that plays important role in germination of seeds is
- A.
Micropyle
- B.
Caruncle
- C.
Arillode
- D.
Hilum
Correct Answer
A. Micropyle -
- 8.
Which of the following statins is NOT metabolised by cytochrome P 450 enzymes?
- A.
Pitavastatin
- B.
Pravastatin
- C.
Lovastatin
- D.
Simvastatin
Correct Answer
B. Pravastatin -
- 9.
Which of the following is an anti-cancer...?
- A.
Cassia angustifoila
- B.
Brucea antidysentrica
- C.
Cephaelis ipecacuanaha
- D.
Cinnamomum zeylanicum
Correct Answer
B. Brucea antidysentrica -
- 10.
Identify a local anaesthetic that does NOT have basic group("atypical") is
- A.
Cocaine
- B.
Procaine
- C.
Benzocaine
- D.
Lidocaine
Correct Answer
C. Benzocaine -
- 11.
Volatile water insoluble content of the fat measured by:
- A.
Polenski value
- B.
Reichert meissle value
- C.
Kraeis test
- D.
Acetyl value
Correct Answer
A. Polenski value -
- 12.
During the carboxylation of clotting factors by vitamin K which amino acid is carboxylated?
- A.
Aspartate
- B.
Glutamate
- C.
Histamine
- D.
Gluatamine
Correct Answer
B. Glutamate -
- 13.
Identify an inappropriate pair:
- A.
Devils trumpet-datura
- B.
Red cherry-colosynth
- C.
May Apple-podophyllum
- D.
Indian saffron-turmeric
Correct Answer
B. Red cherry-colosynth -
- 14.
All aminoglycoside antibiotic are given through intra venous route EXCEPT:
- A.
Kanamycin
- B.
Neomycin
- C.
Sisomycin
- D.
Tobramycin
Correct Answer
B. NeomycinExplanation
given as a powder dosage form
"NEOSPOROIN" is marketed dosage formRate this question:
-
- 15.
Which of these physiological complex is not used as a diagnostic parameter for anaemia?
- A.
Transferritin
- B.
Haemosiderin
- C.
Transferrin
- D.
Haemosiderin
Correct Answer
A. Transferritin -
- 16.
Pheochromocytomas are tumours of:
- A.
Adrenal cortex
- B.
Pancreas
- C.
Pineal gland and hypothalamic region
- D.
Bone marrow
Correct Answer
A. Adrenal cortex -
- 17.
Following are some of the most common polymers used in tablet formulation. Identify Water insoluble polymer?
- A.
Cellulose Acetete Pthalate
- B.
Ethyl Cellulose
- C.
Hydroxy Propyl Methyl Cellulose
- D.
Micro Crysatallne Cellulose
Correct Answer
B. Ethyl Cellulose -
- 18.
Listed below are the drugs belonging to therapeutic class of NSAIDs.Identify one which is used as starting material for Amodiaquine,an antimalarial agent?
- A.
Aspirin
- B.
Paracetamol
- C.
Antharallinic acid
- D.
Ketorolac
Correct Answer
B. Paracetamol -
- 19.
According Indian Pharmacopoeia ,which of the following storage conditions would have to be met for "Injection of insulin I.P" ?
- A.
5 and 5.5
- B.
3 and 3.5
- C.
7 and 7.5
- D.
9 and 9.5
Correct Answer
A. 5 and 5.5 -
- 20.
45-year-old female treated for ovarian cancer develops difficulty hearing. Which of the following agents most likely caused these findings?
- A.
Paclitaxel
- B.
Doxorubicin
- C.
Bleomycin
- D.
Cisplatin
Correct Answer
D. CisplatinExplanation
Cisplatin is preferred for treating ovarian and testicular cancer.However ototoxicity is its major adverse effect.Rate this question:
-
- 21.
The transport process in which molecule is transported into cell while being chemically altered is called:
- A.
Fascilated transport
- B.
Passive transport
- C.
Carrier mediated transport
- D.
Group translocation
Correct Answer
D. Group translocation -
- 22.
Florentine receiver is used to separate the liquids based on:
- A.
Density
- B.
Molecular weight
- C.
Sedimentation rate
- D.
Freezing point
Correct Answer
A. Density -
- 23.
Secretory product associated with pancreatic delta cells:
- A.
Insulin
- B.
Proglucagon
- C.
Pancreatic polypeptide
- D.
Somatostatin
Correct Answer
D. Somatostatin -
- 24.
Caffeine on oxidation with KClO3/HCl would yield:
- A.
Trimethyl alloxam+methyl urea
- B.
Dimethyl Alloxam + Methyl Urea
- C.
Dimethyl alloxam+urea c.
- D.
Methyl alloxam+methyl urea
Correct Answer
B. Dimethyl Alloxam + Methyl Urea -
- 25.
Which of the following secondary plant metabolites can be characterized by reversible complexation with proteins?
- A.
Anthraglycosides
- B.
Tannins
- C.
Saponin
- D.
Alkaloids
Correct Answer
B. Tannins -
- 26.
In India, currently the time period of patent protection is (in years)
- A.
25 years
- B.
10 years
- C.
20 years
- D.
14 years
Correct Answer
C. 20 years -
- 27.
Inherited deficiency of beta-glucosidase will be responsible for which of the following disorder?
- A.
Multiple sclerosis
- B.
Gaucher's disease
- C.
Metachromatic leukodystrophy
- D.
Tay-sachs disease
Correct Answer
B. Gaucher's disease -
- 28.
- A.
A = Multiple paths, B=Longitudinal Equilibration, C=diffusion time
- B.
A= diffusion time ,B= Multiple paths, C= Longitudinal Diffusion
- C.
A= Longitudinal Diffusion, B= Multiple paths, C= diffusion time
- D.
None of the above
Correct Answer
B. A= diffusion time ,B= Multiple paths, C= Longitudinal Diffusion -
- 29.
Kovats retention index (I) for Octane & Nonane for a specified stationary phase would be: (it is dimensionless as is a ratio of retention times)
- A.
Between 800 & 900
- B.
900 & 800 respectively
- C.
8 & 9 respectively
- D.
800 & 900 respectively
Correct Answer
D. 800 & 900 respectively -
- 30.
______ states that “the direction in which the system proceeds back to equilibrium is such that the change is partially offset”
- A.
Le Chatelier's principle
- B.
Gas Law
- C.
Acid Base principle
- D.
Law of Mass action
Correct Answer
A. Le Chatelier's principle -
- 31.
The following options carry the name of the plant, part used and its family. Find a WRONG combination.
- A.
Aegle marmelos, fruit & Rutaceae
- B.
Conium maculatum, fruit & Umbelliferae
- C.
Strophanthus gratus, seed & Scrophulariaceae
- D.
Glycyrrhiza glabra, root and stolon & Leguminosae
Correct Answer
C. Strophanthus gratus, seed & Scrophulariaceae -
- 32.
Which one of the following compounds is useful for the stimulation of cell division and release of lateral bud dormancy?
- A.
Zeatin
- B.
2, 4-Dichlorophenoxyacetic acid
- C.
Indoleacetic acid
- D.
Picloram
Correct Answer
A. Zeatin -
- 33.
Determine the correctness or otherwise of the following Assertion [a] and the Reason [r]: Assertion (a): Tannins are polyphenolic substances occurring in plant cell sap. Hydrolysable and condensed tannins are differentiated by match stick test. Reason (r) : The condensed tannins are resistant to acid hydrolysis therefore stain the lignin present in match stick.
- A.
Both (a) and (r) are true, and (r) is a correct reason for (a)
- B.
Both (a) and (r) are true, but (r) is NOT the correct reason for (a)
- C.
(a) is true but (r) is NOT the correct reason for (a)
- D.
Both (a) and (r) are false
Correct Answer
B. Both (a) and (r) are true, but (r) is NOT the correct reason for (a) -
- 34.
Inhibition/induction of which of the following Cytochrome P450 enzyme system is most likely to be involved in important drug-drug interactions?
- A.
CYP3A4
- B.
CYP2A1
- C.
CYP2D6
- D.
CYP2C9
Correct Answer
A. CYP3A4 -
- 35.
Choose the correct statement about the given four diseases? [P] Cardiomyopathy [Q] Rheumatoid arthritis [R] Myasthenia gravis [S] Ulcerative colitis
- A.
Q & S are autoimmune disorders
- B.
P & Q are autoimmune disorders
- C.
P & R are not autoimmune disorders
- D.
R & S are not autoimmune disorders
Correct Answer
A. Q & S are autoimmune disorders -
- 36.
Blood level monitoring of HbA1c is important in which of the given diseased states?
- A.
Hypercholesterolemia
- B.
Diabetes insipidus
- C.
Diabetes mellitus
- D.
Cardiomyopathy
Correct Answer
C. Diabetes mellitus -
- 37.
Which of the following antibiotics produces concentration dependent bactericidal action and also possesses post-antibiotic effect?
- A.
Azithromycin
- B.
Ceftazidime
- C.
Ciprofloxacin
- D.
Amikacin
Correct Answer
D. Amikacin -
- 38.
If C is the concentration of dissolved drug and Cs is the saturation concentration. In which case the sink conditions are said to be maintained?
- A.
C < 20% of Cs
- B.
C > 20% of Cs
- C.
C < 10% of Cs
- D.
C > 10% of Cs
Correct Answer
C. C < 10% of Cs -
- 39.
Which wavelength of the UV light provides maximum germicidal action?
- A.
253.7mm
- B.
275.5mm
- C.
240nm
- D.
253.7nm
Correct Answer
D. 253.7nm -
- 40.
In addition reactions of alkenes, the Markownikoff’s rule follow...
- A.
Ionic mechanism
- B.
Radical mechanism
- C.
Subtitution mechanism
- D.
Rearrangement mechanism
Correct Answer
A. Ionic mechanism -
- 41.
Erythro isomer on dehydrohalogenation gives
- A.
Trans
- B.
Cis
- C.
Either trans or cis
- D.
Niether trans nor cis
Correct Answer
B. Cis -
- 42.
Anti morkownikoff’s rule is also know as:
- A.
Peroxide effect
- B.
Karasch effect
- C.
Zumas effect
- D.
Both a & b
Correct Answer
D. Both a & b -
- 43.
A free radical is a) shortly lived species b) neutral in nature c) paramagnetic
- A.
A and b are true,c is false
- B.
A and c are true,b is false
- C.
Only b is true
- D.
All are true
Correct Answer
D. All are true -
- 44.
Select an inappropriate sentence about dried stem wood of Picrasma excelsa:
- A.
It does not contain tannins and hence does not show any astringent activities
- B.
It shows false annular rings and bunch of phloem fibers & phloem parenchyma
- C.
The preparations can be utilized in denaturing alcohol
- D.
The most commonly found Allied drugs would be Quassia amara and Brucea antidyssentrica
Correct Answer
B. It shows false annular rings and bunch of phloem fibers & phloem parenchymaExplanation
Its a wood which does not contain phloem or any component of it.Rate this question:
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- 45.
Select the wrong statement regarding Alkaloids:
- A.
Mescaline and colchicines belong to non heterocyclic group of alkaloids
- B.
Most alkaloids are well-defined crystalline substances which unite with acids to form salts
- C.
Most alkaloids does not contain oxygen but a few like conine & nicotine contain oxygen
- D.
Typical alkaloids are derived from plant sources, they are basic, they contain one or more nitrogen atoms(usually in a heterocyclic ring)
Correct Answer
C. Most alkaloids does not contain oxygen but a few like conine & nicotine contain oxygenExplanation
few alkaloids like conine and nicotine does not contain oxygen and are in liquid state.Rate this question:
-
- 46.
In mass spectra, peak with 100% relative abundance is
- A.
Adduct ion peak
- B.
M+2 peak
- C.
Molecular ion peak
- D.
Base peak
Correct Answer
D. Base peak -
- 47.
Typical seawater contains 2.7 g of salt (sodium chloride, NaCl) per 100 mL. What is the molarity of NaCl in the ocean? (The molecular mass of NaCl: 58.44 g/mol)
- A.
0.92 M
- B.
0.13 M
- C.
0.23 M
- D.
0.46 M
Correct Answer
C. 0.23 M -
- 48.
If the Mass spectra of the compound shows 169 and 171 peak of the same intensity, that infers: (molecular weight of compound is 169)
- A.
Presence of Bromine in the compound
- B.
Presence of Nitrogen in the compound
- C.
Presence of any halogen in the compound
- D.
Presence of Chlorine in the compound
Correct Answer
A. Presence of Bromine in the compound -
- 49.
A broad peak in IR spectroscopy at 3450-3500 cm-1 infers:
- A.
Carbonyl Group
- B.
Hydrogen bonded Hydroxy group
- C.
Primary amino group
- D.
Secondary Amino group
Correct Answer
B. Hydrogen bonded Hydroxy group -
- 50.
Which of the following solutions will have highest pH :
- A.
0.1 M NaOH
- B.
0.1 N NaOH
- C.
1% NaOH in water
- D.
1 % NH4OH
Correct Answer
C. 1% NaOH in water -
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Our quizzes are rigorously reviewed, monitored and continuously updated by our expert board to maintain accuracy, relevance, and timeliness.
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Current Version
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Feb 13, 2013Quiz Edited by
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Feb 15, 2012Quiz Created by
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