Pharmaceutical Chemistry - II

Explanation
Depression is a mental health disorder characterized by persistent feelings of sadness, hopelessness, and a loss of interest in activities. It is often accompanied by symptoms such as changes in appetite, sleep disturbances, and difficulty concentrating. While anger and drowsiness can be associated with depression, the primary and most commonly experienced symptom is sadness. This emotion can be overwhelming and persistent, affecting a person's ability to function in their daily life.

Explanation
The given question asks about the duration of a "depression-like feeling." The answer "Short" suggests that this feeling is not prolonged or extended, but rather brief or temporary. This implies that the individual may experience occasional moments of sadness or low mood, but these episodes do not persist for a significant amount of time. Therefore, the correct answer indicates that the depression-like feeling is short-lived.

Explanation
Depression is often associated with changes in appetite and weight, with many individuals experiencing a decrease in appetite and subsequent weight loss. Therefore, the absence of weight loss would not be considered a symptom of depression.

Explanation
Reserpine is a plant alkaloid that is known to cause depression. It works by depleting the levels of certain neurotransmitters, such as serotonin, norepinephrine, and dopamine, in the brain. This depletion of neurotransmitters can lead to a decrease in mood and can cause symptoms of depression.

Explanation
The first treatment of depression was by using MAO Inhibitors. MAO (Monoamine oxidase) Inhibitors are a class of drugs that work by blocking the action of the enzyme monoamine oxidase, which breaks down neurotransmitters like serotonin, dopamine, and norepinephrine. By inhibiting this enzyme, MAO inhibitors increase the levels of these neurotransmitters in the brain, which helps to alleviate symptoms of depression. This class of drugs was one of the earliest developed for the treatment of depression and paved the way for other antidepressant medications.

Explanation
Imipramine is an example of a tricyclic antidepressant. Tricyclic antidepressants are a class of medications used to treat depression. They work by increasing the levels of certain chemicals in the brain that help improve mood. Imipramine specifically inhibits the reuptake of norepinephrine and serotonin, which helps to alleviate symptoms of depression. Phenelzine, on the other hand, is a monoamine oxidase inhibitor used to treat depression, while Salbutamol is a bronchodilator used to treat asthma.

Explanation
Imipramine is a tricyclic antidepressant that belongs to the class of drugs known as azepines. Azepines are a type of heterocyclic compound that contain a seven-membered ring with one nitrogen atom. The parent nucleus of Imipramine is an azepine, which is why the correct answer is "Azepine."

Explanation
Primox is not a brand name of Imipramine. Imipramine is a tricyclic antidepressant medication used to treat depression and bedwetting. Depsonil and Imipratab are both brand names of Imipramine, but Primox is not.

Explanation
Phenelzine is a hydrazine derivative because it contains a hydrazine functional group in its chemical structure. Hydrazine derivatives are compounds that have a hydrazine moiety, which consists of two nitrogen atoms connected by a double bond. In the case of phenelzine, it contains a hydrazine group attached to a phenyl ring, making it a hydrazine derivative. Doxepine and cypromine do not contain the hydrazine functional group in their structures.

Explanation
Amitriptyline is available in tablet form. Tablets are solid dosage forms that contain the active ingredient along with various other excipients. They are designed to be swallowed and are one of the most common and convenient forms of medication. Therefore, the correct answer for this question is tablet.

Explanation
When imipramine is treated with nitric acid, it undergoes oxidation. This oxidation reaction results in the formation of a compound that exhibits a blue color. Therefore, the correct answer is "Blue colour".

Explanation
The correct answer is "Mono amino oxidase". Mono amino oxidase (MAO) is an enzyme that is responsible for the breakdown of certain neurotransmitters such as serotonin, dopamine, and norepinephrine in the brain. It plays a crucial role in regulating mood, behavior, and cognition. The other options, "Mono acidic oxidase" and "Mono amino oleine," do not accurately represent the full form of MAO.