الكويز الحريقة لمادة المايكرو المريعة #3

22 Questions | Total Attempts: 116

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الكويز الحريقة لمادة المايكرو المريعة #3

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Questions and Answers
  • 1. 
    The B- lactams got their name from the characteristic _________ that they all share and the bond that is broken by the ______ that are synthesized by ___________
    • A. 

      Linear structure/ alpha-lactamases / many penicillin resistant bacteria 

    • B. 

      Ring structure /B-lactamases/ many penicillin resistant bacteria 

    • C. 

      Non of the above 

  • 2. 
    A lacatm is 
    • A. 

      Cyclic amine 

    • B. 

      Cyclic amide 

    • C. 

      Linear amide 

  • 3. 
    B-lactam antibiotics types are 
    • A. 

      Monobactam

    • B. 

      Carbapenem 

    • C. 

      Scephalosporins

    • D. 

      Penicillin

    • E. 

      All of the above

  • 4. 
    Naturally penicillin produced by 
    • A. 

      Isolating the penicillin nucleus , 6APA

    • B. 

      Fermentation of moulds 

    • C. 

      A+B

  • 5. 
    Semisynthetic penicillin produced by :
    • A. 

      Isolating the penicillin nucleus , 6APA

    • B. 

      Fermentation of moulds

  • 6. 
    The penicillins sources is/are
    • A. 

      Naturally

    • B. 

      Semisynthetic

    • C. 

      A+B

  • 7. 
    The most important example of naturally penicillin is 
    • A. 

      Benzyl penicillin 

    • B. 

      Cloxacillin 

    • C. 

      Phenoxy methyl pencillin ( penicillin G )

    • D. 

      Phenoxy methyl pencillin ( penicillin V )

    • E. 

      A+C

    • F. 

      A+D

    • G. 

      A+C+D

  • 8. 
    IF phenyl acetic ( phenyl ethanoic ) acid ( C6H5CH2COOH) is added the medium in which the penicillium mould is groowing , ________________ is produced 
    • A. 

      Methicillin

    • B. 

      Cloxacillin

    • C. 

      Benzyl penicillin

  • 9. 
    How is the production of 6-APA ?
    • A. 

      From certain micro organisms produce enzymes , penicillin amidases ( acylases)

    • B. 

      Fermentation from penicillin mould 

    • C. 

      A+B 

  • 10. 
    PENICILLIN acylse's function is :
    • A. 

      Catalyse the removal of the side chain from benzyl penicillin ( penicillin G )

    • B. 

      Added of the side chain to the benzyl penicillin 

    • C. 

      Non of the above 

  • 11. 
    The natural penicillins are based on the original ___________ structure 
    • A. 

      Penicillin V

    • B. 

      Protein 

    • C. 

      Penicillin G

  • 12. 
    NATURAL PENICILLINS EFFECTIVE AGAINST :
    • A. 

      G +ve bacteria such as meningococcus and some G -ve strains of streotococci , staphylococci

    • B. 

      G +ve strains of streptococci , staphylococci and some G -ve bacteri such as meningococcus

  • 13. 
    Natural penicillin include : 
    • A. 

      Penicillin  C , penicillin V, protein 

    • B. 

      Penicillin G , penicillin V , procain 

    • C. 

      Penicillin G, penicillin V , protein 

  • 14. 
    The difference between semisynthetic penicillin and natural penicillin only is :
    • A. 

      Cyclic amide 

    • B. 

      Penicillin V 

    • C. 

      Side chain 

  • 15. 
    Example of Anti-staphylococcal penicillins 
    • A. 

      Ampicillin , methicillin , oxacillin 

    • B. 

      Azlocillin , cloxacillin , dioxacillin 

    • C. 

      Nafcillin , methicillin , oxacillin 

  • 16. 
    Anti-staphylococcal penicillins targets a specific group of bacteria which produce the B-lactamase enzyme/penicillinase- producing staphylococci
    • A. 

      True

    • B. 

      False

  • 17. 
    ______________ is a serious source of naso comial ( hospital-acquired infections )
    • A. 

      G-APA

    • B. 

      DNA

    • C. 

      MRSA

  • 18. 
    For example of broad spectrum penicillins :
    • A. 

      Azlocillin and mezlocillin 

    • B. 

      Ampicillin and amoxacillin 

    • C. 

      Ampicillin and ticarcillin 

  • 19. 
    Resistance to these antibiotics is a major clinical problem because of activation by penicillinase . so , formulations are made by combining these compounds with B-lactamase inhibitors such as calvulanic acid 
    • A. 

      True

    • B. 

      False

  • 20. 
    Which of the following is true ? 
    • A. 

      Ampicillin and amoxicillin have an antibacterial spectrum similar to penicillin V but more effective against G -ve bacteria 

    • B. 

      Ampicillin and ticarcillin have an antibacterial spectrum similar to penicillin G but more effective against G -ve bacteria 

    • C. 

      Ampicillin and amoxicillin have an antibacterial spectrum similar to penicillin G but more effective against G -ve bacteria 

  • 21. 
    ___________- have an activity against pseudomonas aeruginosa 
    • A. 

      Ampicillin and amoxicillin 

    • B. 

      Carbenicillin , ticarcillin , piperacillin 

    • C. 

      Azlocillin , mezlocillin 

    • D. 

      B+C 

  • 22. 
    Extended penicillins are susceptible to inactivation by B-lactamases
    • A. 

      True

    • B. 

      False

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