Choose the correct option

Accidental ingestion of domoic acid leads to profound seizures

Domoic antagonizes effects of GABA

Acute seizure occuring at the time of stroke are more often associated with?

All types of stroke has same propensity to develop seizure

True about Amyotrophic Lateral Sclerosis are all except?

Caused by defects in Superoxide dismutase -2

Sensation and cognition are completely intact

Also known as Lou Gehrig disease

Riluzole is used as a treatment

True statement about MODY

Type 3 MODY is most common variety

Hepatic nuclear factor 1- alpha is least common mutation associated with MODY

MCQ Snacks - Ss (General Medicine) Free Trial 2

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| Written by Mcq Snacks

Mcq Snacks

Community Contributor

Quizzes Created: 14 | Total Attempts: 2,453

Questions: 10 | Attempts: 121 | Updated: Mar 15, 2023

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Questions and Answers

1.

Choose the correct option
- A.
  
  Accidental ingestion of domoic acid leads to profound seizures
- B.
  
  Domoic antagonizes effects of GABA
- C.
  
  Both
- D.
  
  None
Correct Answer
A. Accidental ingestion of domoic acid leads to profound seizures

Explanation
Domoic acid [Crab poisoning] leads to profound seizures due to glutamate receptor agonism.

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2.

Drug to be avoided in Myasthenia gravis?
- A.
  
  Aminoglycosides
- B.
  
  Cephalosporins
- C.
  
  Meropenem
- D.
  
  Linezolid
Correct Answer
A. Aminoglycosides

Explanation
Myasthenia gravis is an autoimmune disorder that affects the muscles and can cause weakness and fatigue. Aminoglycosides are a class of antibiotics that can worsen the symptoms of myasthenia gravis by blocking the release of acetylcholine, a neurotransmitter that is essential for muscle function. Therefore, aminoglycosides should be avoided in patients with myasthenia gravis to prevent exacerbation of symptoms.

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3.

Acute seizure occuring at the time of stroke are more often associated with?
- A.
  
  Embolic stroke
- B.
  
  Thrombotic stroke
- C.
  
  Haemorrhagic stroke
- D.
  
  All types of stroke has same propensity to develop seizure
Correct Answer
A. Embolic stroke

Explanation
Acute seizures occurring at the time of stroke are more often associated with embolic stroke. Embolic strokes are caused by a blood clot that forms elsewhere in the body and travels to the brain, blocking blood flow. These types of strokes are more likely to cause seizures due to the sudden interruption of blood flow and oxygen to the brain. Thrombotic strokes, on the other hand, are caused by a clot that forms within an artery in the brain, while hemorrhagic strokes are caused by bleeding in the brain.

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4.

Antiepileptic to be avoided in patient at risk of developing glaucoma?
- A.
  
  Topiramate
- B.
  
  Lamotrigine
- C.
  
  Levetiracetam
- D.
  
  None
Correct Answer
A. Topiramate

Explanation
Topiramate should be avoided in patients at risk of developing glaucoma because it has been known to increase intraocular pressure, which can worsen glaucoma symptoms or even lead to the development of glaucoma. Lamotrigine and levetiracetam do not have this side effect and are considered safe for patients at risk of glaucoma. Therefore, the correct answer is Topiramate.

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5.

True about Amyotrophic Lateral Sclerosis are all except?
- A.
  
  Caused by defects in Superoxide dismutase -2
- B.
  
  Sensation and cognition are completely intact
- C.
  
  Also known as Lou Gehrig disease
- D.
  
  Riluzole is used as a treatment
Correct Answer
A. Caused by defects in Superoxide dismutase -2

Explanation
Caused by defect in superoxide dismutase 1

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6.

Hepatocellular injury resembling viral hepatitis is caused by
- A.
  
  Carbon tetrachloride
- B.
  
  Acetaminophen
- C.
  
  Androgenic steroids
- D.
  
  Isoniazid
Correct Answer
D. Isoniazid

Explanation
Isoniazid can cause hepatocellular injury resembling viral hepatitis.

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7.

Triad of bronze diabetes comprises of all except
- A.
  
  Hemochromatosis
- B.
  
  Micronodular cirrhosis
- C.
  
  Macronodular cirrhosis
- D.
  
  Diabetes mellitus
Correct Answer
C. Macronodular cirrhosis

Explanation
The triad of bronze diabetes is a combination of three conditions: hemochromatosis, micronodular cirrhosis, and diabetes mellitus. Macronodular cirrhosis is not part of this triad. Macronodular cirrhosis refers to a type of liver cirrhosis characterized by the presence of large nodules in the liver, whereas the triad specifically includes hemochromatosis (excess iron accumulation in the body), micronodular cirrhosis (small nodules in the liver), and diabetes mellitus.

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8.

Type of casts seen in chronic renal failure
- A.
  
  Broad cast
- B.
  
  Glomerular cast
- C.
  
  Hyaline cast
- D.
  
  RBC cast
Correct Answer
A. Broad cast

Explanation
Broad casts are a type of casts that can be seen in chronic renal failure. These casts are characterized by their wide appearance and are formed when there is a significant damage to the renal tubules. They are composed of a mixture of cellular debris, protein, and other substances. The presence of broad casts in the urine indicates severe kidney damage and impaired renal function.

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9.

Most common association of Reactive arthritis is with
- A.
  
  Shigella sonei
- B.
  
  Shigella flexneri
- C.
  
  Yersinia
- D.
  
  Chlamydia
Correct Answer
B. Shigella flexneri

Explanation
Reactive arthritis is commonly associated with Shigella flexneri. This bacterium is known to cause gastrointestinal infections, and in some cases, it can lead to reactive arthritis as an autoimmune response. The other options, Shigella sonei, Yersinia, and Chlamydia, are also known to cause reactive arthritis, but Shigella flexneri is the most common association.

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10.

True statement about MODY
- A.
  
  Autosomal recessive
- B.
  
  Insulin resistance
- C.
  
  Type 3 MODY is most common variety
- D.
  
  Hepatic nuclear factor 1- alpha is least common mutation associated with MODY
Correct Answer
C. Type 3 MODY is most common variety

Explanation
Autosomal dominant
Impairement in insulin secretion
Type 3 is most common [a/w factor 1- alpha mutation]

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MCQ Snacks - Ss (General Medicine) Free Trial 2

Choose the correct option

Drug to be avoided in Myasthenia gravis?

Acute seizure occuring at the time of stroke are more often associated with?

Antiepileptic to be avoided in patient at risk of developing glaucoma?

True about Amyotrophic Lateral Sclerosis are all except?

Hepatocellular injury resembling viral hepatitis is caused by

Triad of bronze diabetes comprises of all except

Type of casts seen in chronic renal failure

Most common association of Reactive arthritis is with

True statement about MODY