Respiratory Pharmacology Test: Trivia Quiz
Respiratory pharmacology test: trivia. There are different illnesses that people suffer from when it comes to the respiratory system and drugs prescribed to ensure the problems are resolved or give the patient some comfortability. In this quiz, you will get to test out just how informed you are when it comes to different drugs, how they are used and why. Do give it a shot and see how well you will do.
Questions and Answers
- 1.
Bronchial asthma is characterised by
- A.
Hyper responsiveness of tracheo-bronchial smooth muscle
- B.
Narrowing of air tubes
- C.
Expulsion of respiratory secretions
- D.
Stimulation of mechano- or chemoreceptors in respiratory passage
Correct Answer(s)
A. Hyper responsiveness of tracheo-bronchial smooth muscle
B. Narrowing of air tubesExplanation
Bronchial asthma is a condition characterized by hyper responsiveness of the tracheo-bronchial smooth muscle and narrowing of the air tubes. This means that the smooth muscles surrounding the airways become overly sensitive and contract excessively, leading to the constriction and narrowing of the air tubes. This narrowing makes it difficult for air to flow freely in and out of the lungs, causing symptoms such as wheezing, shortness of breath, and coughing. Therefore, the hyper responsiveness of the tracheo-bronchial smooth muscle and the resulting narrowing of the air tubes are key features of bronchial asthma.Rate this question:
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- 2.
Entities of COPD includes
- A.
Chronic bronchitis
- B.
Pleural Effusion
- C.
Bronchiectasis
- D.
Bronchiolitis
Correct Answer(s)
A. Chronic bronchitis
C. Bronchiectasis
D. BronchiolitisExplanation
The entities of COPD include chronic bronchitis, bronchiectasis, and bronchiolitis. Chronic bronchitis is a common condition where the bronchial tubes become inflamed and produce excess mucus, leading to a persistent cough. Bronchiectasis is a condition characterized by the widening and scarring of the airways, leading to recurrent infections and difficulty clearing mucus. Bronchiolitis is an inflammation of the bronchioles, the smallest airways in the lungs, often caused by a viral infection. These conditions are all associated with COPD, a progressive lung disease characterized by airflow limitation and difficulty breathing.Rate this question:
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- 3.
What is Zileuton?
- A.
Cox 2 inhibitor
- B.
Mast cell stabilizer
- C.
5-LOX inhibitor
- D.
PDE inhibitor
Correct Answer
C. 5-LOX inhibitorExplanation
Zileuton is a 5-LOX inhibitor. 5-LOX (5-lipoxygenase) is an enzyme involved in the production of leukotrienes, which are inflammatory mediators. By inhibiting 5-LOX, zileuton helps to reduce inflammation and is commonly used in the treatment of asthma. It works by blocking the production of leukotrienes, which are known to cause bronchoconstriction and inflammation in the airways. Therefore, zileuton is not a Cox 2 inhibitor, mast cell stabilizer, or PDE inhibitor, but specifically targets 5-LOX to reduce inflammation.Rate this question:
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- 4.
Symptoms of COPD worsens during the night.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
COPD stands for Chronic Obstructive Pulmonary Disease, which is a progressive lung disease. The symptoms of COPD, such as shortness of breath and coughing, can worsen during physical activity or exposure to triggers like smoke or pollution. However, there is no specific evidence to suggest that COPD symptoms worsen specifically during the night. Therefore, the statement is false.Rate this question:
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- 5.
Which of the following drug will cause Churg-Strauss syndrome?
- A.
Fluticasone
- B.
Omalizumab
- C.
Ketotifen
- D.
Montelukast
Correct Answer
D. MontelukastExplanation
Montelukast is the correct answer because it has been associated with the development of Churg-Strauss syndrome. Churg-Strauss syndrome is a rare autoimmune condition characterized by inflammation of blood vessels, which can affect various organs. Montelukast is a leukotriene receptor antagonist commonly used in the treatment of asthma and allergic rhinitis. Although the exact mechanism is not fully understood, it is believed that Montelukast may trigger an immune response leading to the development of Churg-Strauss syndrome in susceptible individuals. Fluticasone, Omalizumab, and Ketotifen are not known to be associated with Churg-Strauss syndrome.Rate this question:
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- 6.
Select the true statement.
- A.
Corticosteroids afford more complete and sustained symptomatic relief than bronchodilators
- B.
Ketotifen is a bronchodilator and will not produce sedation
- C.
Atropinic drugs cause bronchodilatation by blocking M1 receptor
- D.
Cysteinyl leukotrienes (LT-C4/D4) are important mediators of bronchial asthma.
Correct Answer(s)
A. Corticosteroids afford more complete and sustained symptomatic relief than bronchodilators
D. Cysteinyl leukotrienes (LT-C4/D4) are important mediators of bronchial asthma.Explanation
Corticosteroids are known to provide more complete and sustained symptomatic relief compared to bronchodilators. This is because corticosteroids work by reducing inflammation in the airways, which is a key factor in asthma symptoms. On the other hand, bronchodilators primarily work by relaxing the muscles around the airways, allowing for easier breathing. While bronchodilators can provide immediate relief, corticosteroids are more effective in reducing inflammation and preventing future asthma attacks. Additionally, cysteinyl leukotrienes (LT-C4/D4) are indeed important mediators of bronchial asthma, further supporting the given answer.Rate this question:
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- 7.
Which of the following drug is believed to increase bronchial secretion?
- A.
Ambroxol
- B.
Guaiphenesin
- C.
Pholcodine
- D.
Promethazine
Correct Answer
B. GuaiphenesinExplanation
Guaiphenesin is believed to increase bronchial secretion. It is an expectorant that works by thinning and loosening mucus in the airways, making it easier to cough up. This helps to clear the airways and improve breathing in conditions such as bronchitis, asthma, and other respiratory conditions. Ambroxol is also an expectorant, but it is primarily used to treat respiratory conditions by increasing the production of surfactant in the lungs, which helps to keep the airways open. Pholcodine is a cough suppressant, and promethazine is an antihistamine and antiemetic.Rate this question:
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- 8.
Which of the following drug may lead to chronic cough on long term use?
- A.
Enalapril
- B.
Betamethasone
- C.
Losartan
- D.
Quinidine
Correct Answer
A. EnalaprilExplanation
Enalapril is an angiotensin-converting enzyme (ACE) inhibitor commonly used to treat hypertension and heart failure. One of the side effects associated with long-term use of ACE inhibitors is a chronic cough. This cough is believed to be caused by an increase in levels of bradykinin, a substance that can irritate the airways and lead to coughing. While the other drugs listed may have side effects, chronic cough is not commonly associated with their long-term use.Rate this question:
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- 9.
Dextromethorphan is a synthetic central NMDA receptor agonist.
- A.
True
- B.
False
Correct Answer
B. FalseExplanation
Dextromethorphan is not a synthetic central NMDA receptor agonist.Rate this question:
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- 10.
Select the true statement.
- A.
Opioids suppress the cough reflex by direct action on the cough center in the medulla
- B.
A demulcent is an agent that forms a soothing film over a mucous membrane
- C.
Sodium and potassium citrate will irritate the airway mucosa
- D.
Ambroxol is effective in treating dry cough
Correct Answer(s)
A. Opioids suppress the cough reflex by direct action on the cough center in the medulla
B. A demulcent is an agent that forms a soothing film over a mucous membraneExplanation
Opioids suppress the cough reflex by directly acting on the cough center in the medulla. This means that opioids have a direct effect on the part of the brain responsible for initiating the cough reflex, causing it to be suppressed. A demulcent, on the other hand, is an agent that forms a soothing film over a mucous membrane. This film provides a protective barrier and helps to alleviate irritation and inflammation. Therefore, the statement that opioids suppress the cough reflex by direct action on the cough center in the medulla is true, while the statement about demulcents is also true.Rate this question:
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