Effects And Uses Of Drugs
- 1.Which of the following is not a function of drugs?
- A.
Diagnosis
- B.
Prevention
- C.
Treatment
- D.
None of the above
- 2.Which of the following is not one of the body control systems on which drugs act upon?
- A.
Receptors
- B.
Ion channels
- C.
Genetic apparatus
- D.
Enzymes
- E.
Carrier proteins
- 3.Which of the following is not true about Gq-proteins
- A.
Increases DAG
- B.
Increases intracellular Ca+2 ions
- C.
Activates tyrosine kinase C
- D.
Linked to alpha-1 adrenergic receptors
- E.
None of the above
- 4.Which of the following is common between between DNA-linked receptors and NO receptors
- A.
They are found inside the cells
- B.
They both act on genetic apparatus
- C.
The action of both of them depends on the formation of a second messenger
- D.
They modify protein production
- E.
All of the above
- 5.Which of the following is common between agonists and antagonists
- A.
They have the same rate of association and disassociation
- B.
They both have affinity
- C.
They both have efficacy
- D.
Two of the above
- 6.Which of the following is used to calculate the effectiveness of the drug in relation to its dose
- A.
Emax
- B.
ED50
- C.
Therapeutic index
- D.
Steepness of slope of the dose-effect graph
- E.
Two of the above
- 7.Which of the following parameters can't be obtained from a quantal-dose curve
- A.
Emax
- B.
ED50
- C.
LD50
- D.
Safety index
- E.
None of the above
- 8.Which of the following regarding chronopharmacology is not correct?
- A.
Attacks of bronchial asthma are common at night
- B.
Circadian variation of sympathetic activity causes MI in mornings
- C.
Antihistamine treatment should be given at midnight
- D.
Irritant drugs should be given after meals
- E.
None of the above
- 9.A child is 5 years old and the dose of a drug he takes is 10mg.Find the adult dose
- A.
34mg
- B.
43mg
- C.
12mg
- D.
51mg
- 10.Which of the following drugs needs to be present in order to cause malignant hyperthermia
- A.
Succinylcholine
- B.
Halothane
- C.
Barbiturates
- D.
Sulphonamides
- E.
Succinylcholine and halothane together
- 11.Which of the following drugs do not cause porphyrias in a person having genetic defeciency in second enzyme converting porphyrin to heme
- A.
Barbiturates
- B.
Aminoglycosides
- C.
Sulphonamides
- D.
Drugs stimulating ALA synthase
- E.
None of the above
- 12.Which of the following drugs cause hemolytic anemia due to G6PD defeciency
- A.
Fava beans
- B.
Antimalarials
- C.
Sulphonamides
- D.
All of the above
- 13.The synthesis of which of the following clotting factors is not inhibited by warfarin
- A.
2
- B.
9
- C.
7
- D.
10
- E.
None of the above
- 14.Which of the following match in teratogenic drugs is incorrect
- A.
I131-->fetal goiter
- B.
Antiepileptics-->cleft palate
- C.
Thalidomide-->fetal anomalies
- D.
Teracyclins-->dental hypoplasia
- 15.Iatrogenic diseases are of which type of adverse reactions
- A.
A
- B.
B
- C.
C
- D.
D
- E.
E
- 16.Metronidazole induces which of the following type D reactions
- A.
Carcinogenecity
- B.
Teratogenecity
- C.
Mutagenecity
- D.
All of the above
- 17.Drug dependence is of which type of adverse effects
- A.
A
- B.
B
- C.
C
- D.
D
- E.
E
- 18.Hypertension adverse effect is caused by which of the following
- A.
Stoppage of clonidine
- B.
Stoppage of B-adrenergic blockers
- C.
Corticosteroids chronic use
- D.
Two of the above
- E.
All of the above
- 19.Which of the following effects occur at therapeutic dose
- A.
Side effects
- B.
Seizure due to lidocaine
- C.
Toxic effect
- D.
Intolerance
- E.
Two of the above
- 20.Oral anticoagulants cause which of the following
- A.
Hepatotoxicity
- B.
Analgesic nephropathy
- C.
Addisonian crisis on stoppage
- D.
Thromboembolism
- E.
None of the above
- 21.Which of the following relating to methods of drug transport is incorrect
- A.
Facilitated diffusion involves transport of substances across ion channels
- B.
Active transport moves substances against concentration gradient
- C.
Pinocytosis uses energy
- D.
Carrier mediated transport is subjected to saturation and competition
- E.
None of the above
- 22.Which of the following is incorrect about transport factors related to drugs
- A.
Inorganic substanes are better absorbed than organic
- B.
Solutions are better absorbed than suspensions
- C.
More lipid soluble drugs are absorbed better than less lipid soluble ones(provided both have same solubility for water)
- D.
Ferric is better absorbed than ferrous
- E.
None of the above
- 23.A drug of weak basicity has a pKa of 3 and the ratio of unionized base to ionized base is 2:3.Find the pH of the medium containing the drug(correct to 2 decimal places)
- A.
2.82
- B.
3.18
- C.
4.02
- D.
2.37
- 24.Which of the following body mechanisms is most useful in toxicity treatment of drugs with high pKa in the urine
- A.
Increasing pH of the urine
- B.
Decreasing pH of the urine
- C.
Increasing pH of plasma filtered
- D.
Decreasing pH of plasma filtered
- 25.Which of the following drugs is most absorbed by the stomach
- A.
Acidic drug
- B.
Basic drug
- C.
Neutral drug
- D.
All have the same absorbance
Questions: 9 | Attempts: 37565 | Last updated: Jul 6, 2020
-
Sample QuestionYour Favorite Drug is?:
Questions: 38 | Attempts: 29676 | Last updated: Oct 28, 2020
-
Sample QuestionWhat is the purpose of pre-clinical testing?
Questions: 5 | Attempts: 5326 | Last updated: Sep 11, 2019
-
Sample QuestionTridil ids classified as what type of a drug?
Back to top