Med Chem Practice Exam 3

130 Questions | Total Attempts: 125

SettingsSettingsSettings
Med Chem Practice Exam 3 - Quiz

Questions and Answers
  • 1. 
    Prontosil rubrum is under what class of antimicrobials?
  • 2. 
    Sulfonamides inhibit ________________ enzyme, an important enzyme needed for the biosynthesis of folic acid derivatives.
  • 3. 
    Sulfonamides inhibit the biosynthesis of folic acid by competing at the active site with _________________, a normal structural component of folic acid derivatives.
  • 4. 
    _______________ stands out from the typical sulfonamide by the fact that although administered orally, the drug is not absorbed in the gut, so the majority of the drug is delivered to the distal bowel.
  • 5. 
    Name an active component of sulfasalazine.
  • 6. 
    Trimethoprim inhibits ______________ enzyme, and thus prevents biosynthesis of folic acid derivatives.
  • 7. 
    What is the main chemical structure of quinolones?
  • 8. 
    Quinolones are rapidly bactericidal, largely as a consequence of inhibition of ______________ enzyme. 
  • 9. 
    Quinolones were of little significance until the discovery that the addition of a ___________ group to the 6-position of the basic nucleus greatly increased the biological activity.
  • 10. 
    ______________ is used for the disinfection of acidic urine.
  • 11. 
    Methenamine is a low-molecular-weight polymer of ___________ and ___________.
  • 12. 
    Name the structure:
  • 13. 
    Name the structure:
  • 14. 
    Name the structure:
  • 15. 
    Name the structure:
  • 16. 
    Name the structure:
  • 17. 
    Small molecules that are not inherently antigenic but that react with proteins to produce antigens in this manner are called____________
  • 18. 
    Name the class of antibiotics:
  • 19. 
    ____________ 
  • 20. 
    Antibiotics are most often administered at a bactericidal / bacteriostatic dose to prevent bacterial multiplication and help the immune system fight the infection. (Choose one answer)
  • 21. 
    Gram-positive / Gram-negative bacteria are stained blue by a methyl violet/iodine staining process (choose one).
  • 22. 
    Gram-positive / Gram-negative microorganisms do not retain the methyl violet–iodine stain when washed with alcohol but, rather, are colored pink when subsequently treated with the red dye safranin. (choose one)
  • 23. 
    • A. 

      Persistence

    • B. 

      Resistance

    • C. 

      Postantibiotic effect

    • D. 

      Biphasic effect

    • E. 

      Inoculum effectin

  • 24. 
    • A. 

      Sulfonamide

    • B. 

      Quinoline

    • C. 

      Trimthoprin

    • D. 

      Methenamine

  • 25. 
    • A. 

      Guanosine

    • B. 

      Adenosine

    • C. 

      Cytidine

    • D. 

      Thymidine

Back to Top Back to top