Laboratory Technologies For Detection Of Large Rearrangements In Genes

9 Questions | Total Attempts: 221

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Laboratory Quizzes & Trivia

Instructions to participants: All participants are encouraged to answer questions 6-9. Participants registered to earn CEUs are required to answer questions 1-5 and score a minimum of 80% (4/5 correct). You will be able to re-take the quiz until a passing score is reached. Participants who are not interested in CEU credit, please select the "Not interested in CEU credit" option for questions 1-5 and answer only questions 6-9.


Questions and Answers
  • 1. 
    Sanger sequencing is the most common method used for DNA sequencing.  Which statement BEST describes Sanger Sequencing?
    • A. 

      A. This method detects point mutations.

    • B. 

      B. This method detects large rearrangements.

    • C. 

      C. This method requires a PCR step for DNA amplification.

    • D. 

      D. A and C.

    • E. 

      E. Not interested in CEU credit

  • 2. 
    If a gene deletion includes one or both primer binding sites for an amplicon, the PCR product from that gene segment is typically not produced.
    • A. 

      True

    • B. 

      False

    • C. 

      Not interested in CEU credit

  • 3. 
    The following are disadvantages of MLPA
    • A. 

      A. Requires high quality DNA

    • B. 

      B. SNPs can cause technical artifacts

    • C. 

      C. It is not quantitative

    • D. 

      D. A and B

    • E. 

      E. All of the above

    • F. 

      F. Not interested in CEU credit

  • 4. 
    Southern blot is a technology that uses:
    • A. 

      A. Restriction enzymes and gel electrophoresis

    • B. 

      B. Control DNA and competitive binding to a chip

    • C. 

      C. Oligonucleotides and a unique “stuffer” sequence

    • D. 

      D. Di-deoxynucleotides and comparison to a reference sequence

    • E. 

      E. Not interested in CEU credit

  • 5. 
    On a microarray, patient DNA and control DNA bind competitively to probes.
    • A. 

      True

    • B. 

      False

    • C. 

      Not interested in CEU credit

  • 6. 
    Did the webcast improve your knowledge about laboratory technologies? 
    • A. 

      Yes

    • B. 

      No

  • 7. 
    Was the information presented useful to you? 
    • A. 

      Yes

    • B. 

      No

  • 8. 
    How could this webinar have been improved?
  • 9. 
    What additional topics would you like to see presented?