Immuno I

46 Questions

Settings
Please wait...
Inflammation Quizzes & Trivia

.


Questions and Answers
  • 1. 
    List the 6 fractions seen in serum electrophoresis
  • 2. 
    What are the three APS antibodies?
  • 3. 
    List the 3 common symptoms for APS  
  • 4. 
    Seen with high antibiotic usage, no medical significance. May also be seen in pancreatitis
    • A. 

      Hypoalbuminemia

    • B. 

      Bisalbuminemia

    • C. 

      Chronic inflammation

    • D. 

      Fibrinogen

  • 5. 
    See in chronic malnutrition, decrease synthesis due to cirrhosis, hepatitis, inflammation or loss due to nephrotic syndrome, burns, gastroenteropathy and increased metabolism: thyrotoxicosis, Cushing's and severe inflammation
    • A. 

      Bisalbuminemia

    • B. 

      Hyperalbuminemia

    • C. 

      Hypoalbuminemia

    • D. 

      Acute Inflammation

  • 6. 
    Acute inflammation leads to... 
    • A. 

      Increase in alpha 1(antitrypsin) & alpha 2 (haptoglobin)

    • B. 

      Increase in alpha 1, decrease in albumin

    • C. 

      Decrease in alpha 1 and alpha 2 

    • D. 

      Decrease albumin, alpha 2 increase, gamma increase

  • 7. 
    Chronic inflammation leads to.... 
    • A. 

      Increase alpha 1 & alpha 2

    • B. 

      Decrease in albumin, increase in gamma and increase in alpha 2

    • C. 

      Increase in albumin, decrease in alpha 1 & 2

    • D. 

      Decrease in gamma, increase in albumin

  • 8. 
    Transferrin in anemia would cause...
    • A. 

      Increase alpha 1

    • B. 

      Decrease alpha 2

    • C. 

      Decrease in beta 1

    • D. 

      Increase in beta 2

  • 9. 
    A decrease in the beta 2 region can be due to...
    • A. 

      Anemia

    • B. 

      Hemolysis

    • C. 

      Old serum or increased C3 complement consumption

    • D. 

      Fibrinogen

  • 10. 
    Extra bands in the Alpha 2 region is due to...
    • A. 

      Fibrinogen

    • B. 

      Hemolysis

    • C. 

      Old serum

    • D. 

      Increased complement consumption

  • 11. 
    Fibrinogen can lead to..
    • A. 

      Peak in albumin region

    • B. 

      Decrease in Beta 2 region

    • C. 

      Peak in Beta 2 region

    • D. 

      Extra bands in beta 2 region

  • 12. 
    Beta gamma bridging is due to...
    • A. 

      Hemolysis

    • B. 

      Alcoholic cirrhosis

    • C. 

      Hepatitis

    • D. 

      Anemia

  • 13. 
    • Primary immuodeficiency 
    • Secondary to immuosuppressive therapy
    • Light chain myeloma
    • A. 

      Beta gamma bridging

    • B. 

      Hypogammaglobulinemia

    • C. 

      Polyclonal hyperglobinemia

    • D. 

      Oligoclonal pattern

  • 14. 
    Can be caused by:
    • AIDS
    • Hepatic infections
    • Autoimmune diseases
    • Chronic inflammations
    • A. 

      Hypogammaglobulinemia

    • B. 

      Hyperglobulinemia (Polyclonal)

    • C. 

      Oligoclonal

    • D. 

      Chronic inflammation

  • 15. 
    Can be caused by:
    • Autoimmune diseases (Lupus, RA)
    • Antibodies against viral proteins
    • Autoimmune response in transplant patients 
    • A. 

      Beta-gamma bridging

    • B. 

      Hypogammaglobulinemia

    • C. 

      Hyperglobulinemia

    • D. 

      Oligoclonal Pattern

  • 16. 
    • Plasma cell clone produces a monoclonal light chain
    • Bence Jones protein
    • A. 

      MGUS

    • B. 

      SMM

    • C. 

      MM

    • D. 

      AL AMYLOIDOSIS

  • 17. 
    • IgM monoclonal
    • Hyperviscosity 
    • Hypercellular bone marrow with extensitve infiltration by lymophoplasma cells 
    • A. 

      AL AMYLOIDOSIS

    • B. 

      MGUS

    • C. 

      SMM

    • D. 

      WALDENSTROM'S

  • 18. 
    Described as destruction of joints and skin rash after exposure to sunlight. Immune complex destruction causes glomerulonephritis 
    • A. 

      SLE

    • B. 

      Multipile sclerosis

    • C. 

      RA

    • D. 

      Goodpasture's syndrome

  • 19. 
    Combination of 
    • SLE
    • Scleroderma
    • Polymyositis
    • A. 

      SLE

    • B. 

      MCTD

    • C. 

      Multiple Sclerosis

    • D. 

      Myasthenia Gravis

  • 20. 
    • Inflammation of lacrimal and salivary glands
    • Dry eyes & mouth, fatigue and Raynaud;s
    • Arthritis and hashimoto's thyroiditis are often present
    • A. 

      SLE

    • B. 

      MCTD

    • C. 

      Sjoren's syndrome

    • D. 

      Scleroderma

  • 21. 
    • Connective tissue disorder
    • Thickening of the skin, scarring, blood vessel damage, Raynauds
    • Localized or systemic with systemic being diffuse or limited
    • CREST variant
    • A. 

      SLE

    • B. 

      Sjogren's syndrome

    • C. 

      Polyomitis

    • D. 

      Scleroderma

  • 22. 
    • Muscle weakness
    • Dx by biopsy
    • Antibody that cross reacts with CMV
    • A. 

      RA

    • B. 

      SLE

    • C. 

      Polymyositis

    • D. 

      Sjogren's syndrome

  • 23. 
    Type question here. Example: Practice makes you [Blank]
  • 24. 
    APS is an [Blank] disease
  • 25. 
    Patient's with APS have a tendency for THROMBOSIS, not bleeding
    • A. 

      True

    • B. 

      False

  • 26. 
    What is required for Anti-phospholipid syndrome?
    • A. 

      Just having APS antibodies

    • B. 

      Just clinical presentations

    • C. 

      Both APS and clinical presentations

  • 27. 
    What is the diagnostic criteria for APS?
    • A. 

      Clinical presentation, APS antibody negative

    • B. 

      Clinical presentation, APS antibody positive & 2nd positive after 6 wks

    • C. 

      Clinical presentation, APS antibody positive & 2nd positive after 12 wks

  • 28. 
    [Blank] is a cardiovascular risk factor that puts you at a higher risk for APS (esp. APS abs)
  • 29. 
    What is used at Northshore?
    • A. 

      Bioplex - multiplex EIA

    • B. 

      Biorad - single EIA

    • C. 

      Rosche

  • 30. 
    APS pregnant women should use?
    • A. 

      Coumadin

    • B. 

      Tylenol

    • C. 

      LMW heparin

    • D. 

      Heparin

  • 31. 
    APS prevalence is [Blank] %
  • 32. 
    Which is the delayed type of hypersensitivity?
    • A. 

      Type 1

    • B. 

      Type 2

    • C. 

      Type 3

    • D. 

      Type 4

  • 33. 
    Complement is not involved in...
    • A. 

      Type 1 & 2

    • B. 

      Type 2 & 3

    • C. 

      Type 1 & 4

    • D. 

      All of the types

  • 34. 
    Examples are Anaphylaxis, hay fever and food allergies and asthma 
    • A. 

      Type 1

    • B. 

      Type 2

    • C. 

      Type 3

    • D. 

      Type 4

  • 35. 
    Examples of this hypersensitivity is SLE, RA, Serum Sicknes, Arthus rxn Time course is hours to days 
    • A. 

      Type 1

    • B. 

      Type 2

    • C. 

      Type 3

    • D. 

      Type 4

  • 36. 
    Examples include; transfusion rxns, autoimmune hemolytic anemia, HDN, autoimmune organ destruction
    • A. 

      Type 1

    • B. 

      Type 2

    • C. 

      Type 3

    • D. 

      Type 4

  • 37. 
    Symptoms of thryotoxicosis Associated with HLA DR Most COMMON autoimmune disease  
    • A. 

      SLE

    • B. 

      Hashimoto's

    • C. 

      Grave's disease

    • D. 

      MCTD

  • 38. 
    What is the best way to test for RA? Test for...
    • A. 

      Anti-CCP

    • B. 

      Anti- centromere

    • C. 

      Anti-Jo1

    • D. 

      Anti SSB

  • 39. 
    Linked to HLA D4 - IgM/IgG complexes deposit in the joints causing Type II hypersensitivity  
    • A. 

      SLE

    • B. 

      RA

    • C. 

      Grave's

    • D. 

      Hashimoto's