These are the questions from AFP, answers from them too. Except for getting this journal I'm not affiliated with it otherwise. There are a few double ups, and more questions will be added when I get a chance.
Toxindrome refers to symptoms and signs of a medically significant spider bite
Neurotoxic effects are typically caused by toxins released by Loxosceles species
Cytotoxic effects are typically caused by toxins released by Latrodectus species
Araneism refers to the local clinical signs resulting from a spider bite
Arachnidism refers to an irrational fear of spiders
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All children require immediate antivenom
Antivenom is not suitable or approved for use in children
If Lola’s pain is not controlled by simple analgesia
If Lola has systemic signs of envenomation that are not adequately managed by IV fluids
Antivenom is not recommended in atopic people as allergy is very common
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Envenomation by this spider is usually mild, although it has 88% homology with venom from a more dangerous spider
A pressure immobilisation bandage and immediate transfer to hospital is required
Envenomation by this spider causes similar effects to lacrodectism and should be considered if she fails to respond to red back spider antivenom
This spider occurs throughout mainland Australia
Fasciculation are very rate manifestations of envenomation by this spider
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Petechiae indicate dengue haemorrhagic fever which requires hospitalisation
Petechiae indicate significant thrombocytopenia requiring platelet transfusion
Petechiae may occur in uncomplicated dengue fever
Thrombocytopenia occurs in around 75% of cases of dengue fever
Thrombocytopenia occurs mainly in patients with a past history of malaria
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Serum dengue PCR can detect virus between day 7 and 14 of the illness
Serum IgG becomes positive after 4 – 5 days of infection
No cross reactivity occurs between other flavivirus IgG
Three blood films are important investigations for Michael
Full blood count is not useful as Michael is already at day 4 of his illness
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Is likely to be currently infected with another flavivirus
Has dengue haemorrhagic fever
Is immune to dengue and does not currently have the disease
Has immunity to all four arbovirus serotypes
Likely has infection by a second dengue serotype
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A drop of haematocrit by > 20% from baseline
Platelet count < 80 000 cells per cubic mm
Postural hypotension
Development of severe abdominal pain
Development of significant bleeding
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< 25% are unprovoked attacks
> 75% are unprovoked attacks
> 75% are by a dog known to the victim
Female unsterilized dogs are higher risk
Children less than 5 years of age are at higher risk
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An intercanine distance of 3 – 5 cm is suggestive of a child bite
Human bites have high complication and infection rates than animal bites
HIV prophylaxis should be administered in all human bites
Hepatitis B immunoglobulin should be administered in all human bites
Most human bites are complicated by infective endocarditis
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Staphylococcus aureus are flora of humans and dogs
Pasturella aerogenes are flora of pigs and cats
Actinobacillus are flora of cows and rodents
Clostredium tetani are flora of monkeys
Streptobacillus moniliformis are flora of dogs
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Wounds over a prosthetic joint
Wounds on the trunk
Wounds with delayed presentation by more than 8 hours
Puncture and crush wounds
Wounds to the genitals
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Dark spotting on the bed from blood spillage
Dark spotting on the bed from faecal deposition
Presence of the small oval, winged insects themselves
Typical distribution over trunk and feet
Typical distribution in lattice pattern
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Reactions always occur within 3 days
Most bites occur in a linear pattern
The classic wheal reaction is < 1cm diameter
Bullous eruptions are very uncommon
Numerous bites can present as urticaria or an erythematous rash
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Anaphylaxis is a common reaction
Secondary infection is very uncommon
Although itchy, ulceration from scratching does not occur
Fever and malaise may occur in some individuals
Infections such as malaria and HIV are common sequelae
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There are no treatments available
Bed bugs are easily killed with simple home insect sprays
Symptomatic treatment with antihistamines and topical steroids is useful
Bed bugs infestations cannot be treated, necessitating all new furnishings
Commercial personal lice treatment is sufficient in the majority of cases
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To lose 30% of their excess weight
To lose 50 - 60% of their excess weight
To lose 50 - 60% of their weight
To lose 70 - 90% of their excess weight
To lose 70 - 90% of their weight
A port complication
Erosion of the band into the stomach cavity
Acute food bolus obstruction
Acute slip with obstruction and ischaemia
Symmetrical pouch dilatation
Barium swallow is indicated
Gastroscopy is indicated
The volume of fluid within the system should be checked repeatedly
A carbonated beverage may provide relief
No investigation is indicated
A normal 19 gauge needle can be used
You enter at 45 degrees to the skin to access the port
A Huber tipped needle is preferred
You feel the upper border of the port with the needle
The port must never be accessed except by the managing surgeon
Anti-saccharomyces cerevisiae antibody (ASCA) is specific to Crohn disease (CD)
Atypical perinuclear antineutrophil cytoplasmic antibody (p-ANCA) is specific to ulcerative colitis (UC)
ASCA and p-ANCA cannot differentiate CD from UC
Calprotectin is a faecal marker specific to CD
Lactoferrin is a faecal marker specific to UC
5-ASA drugs are poorly tolerated
5-ASA drugs have low compliance rates
5-ASA drugs have a high incidence of adverse effects
5-ASA drugs are more effective orally than rectally for UC proctitis
The use of 5-ASA drugs is best established in CD
CRP does not correlate to disease activity
Persistently elevated CRP correlates to a lower relapse rate
Persistently elevated CRP correlates to a lower response to infliximab
Some patients do not mount a CRP response to intestinal inflammation
CRP is a useful indicator if it is in the normal range
Infliximab has no efficacy for UC
Infliximab is funded by the PBS for use in UC
Infliximab must be given by subcutaneous injection
Infliximab is used monthly for maintenance treatment
Infliximab binds tumour necrosis factor alpha
Abnormalities of central pain processing
Postsurgical changes
Genetic factors
Sensory dysfunction
Postinflammatory changes
Different strains of probiotics appear to target different dominant symptoms
The probiotic species are now part of her permanent bowel flora
There is no evidence that probiotics are useful for abdominal pain
There is no evidence that probiotics are useful for global IBS symptoms
There is no evidence that probiotics are useful for abdominal bloating
Perianal staining from the oil is a common side effect
Peppermint oil is known to be safe during pregnancy
Reflux may occur due to oesophageal sphincter relaxation
Peppermint oil is contraindicated in people with asymptomatic gallstones
Peppermint oil is contraindicated in all forms of liver disease
There is no evidence the soluble fibre improves IBS related abdominal pain
There is no evidence that soluble fibre improves IBS related constipation
There is no evidence that soluble fibre improves global IBS symptoms
Soluble fibre is not fermented or digested in the gut
Soluble fire acts by retaining water thereby increasing stool bulk
Fructose requires fructase in the brush border for digestion
Fructose absorption is impaired by luminal glucose
Fructose is absorbed via a low capacity carrier mediated facilitated diffusion
Lactose absorption is increased by luminal glucose
Some individuals have no lactase present and therefore cannot digest lactose
100mL regular milk
50g swiss cheese
200g cottage cheese
100g yoghurt
50g ice-cream
Sorbitol is a synthetic sweetener added to many foods
Sorbitol rarely occurs in fructose containing foods
Fructans are storage carbohydrates in Graminaceae plant species, such as wheat
Fructans are in high concentrations in corn and rice
Fructans are storage carbohydrates in Compsitae plant species, such as asparagus
Alternating bowel habit
Rectal bleeding
Anaemia
Weight loss
None of the above
Women with gestational diabetes require yearly screening
Women with diabetes who become pregnant require screening each trimester
Those with renal disease require yearly screening
Those with proliferative DR require ophthalmology review within 1 week
Those with nonproliferative DR require review within 4 weeks
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The commonest mechanism is proliferative DR
The commonest mechanism is macular oedema
She has approximately a 25% chance of having DR now
50% of people in her position will require treatment to prevent visual loss
None of the above
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The duration of diabetes is the strongest predictor of DR
Co-existent hypertension is the strongest predictor of DR
Diabetic control is the strongest predictor of DR
Blood pressure control has not been found to reduce DR
Tight diabetic control has been found to reduce DR
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Is characterised by optic disc swelling
Is characterised by early neovascularisation
Is characterised by cottonwool spots
Must be screened for yearly in patients with hypertension
Is predictive of adverse cardiovascular outcomes
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Visual loss is commonly associated with classic migraine
Occipitobasal headaches with visual loss are typical of migraine
Tunnel vision may occur
Aura classically beings temporally
Typical negative scotoma includes zigzag lights
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Onset of visual loss over several hours
Visual loss preceded by flashing lights
Visual loss progresses like a 'curtain' from the periphery
Unexplained weight loss
Recent ophthalmic surgery
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Thrombocytopenia increases the probability of GCA 6-fold
Temporal artery biopsy must be performed before commencement of therapy
ESR is the most sensitive diagnostic test for GCA
An ESR of < 29 would be considered normal for Alphons
A normal ESR excludes GCA in Alphons' case
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Temporal artery tenderness
Proptosis
Papilloedema
Homonymous field defect
Eye movement disorders
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Retinal pallor may indicate retinal detachment
Dilated vessels may indicate retinal artery occlusion
A cherry red macular is a normal finding
A cherry red macular may indicate papilloedema
Widespread nerve fibre layer haemorrhages may indicate retinal artery occlusion
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Vitreous haemorrhage typically produces a discrete black scotoma
Subhyaloid haemorrhage typically presents as a 'shower of black dots'
Subretinal haemorrhage typically presents as a discrete brown scotoma
Vitreous haemorrhage is typically painful
Subhyaloid haemorrhage typically produces a mobile scotoma
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Transoesophageal echocardiogram
CT angiography
Fundus fluorscein angiography
CT brain and orbits
ESR and CRP
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A 'curtain' descending over the visual field is typical
Central vision preservation requires especially urgent referral
The pupil must not be dilated as this will exacerbate the detachment
Urgent ultrasound imaging is essential for all patients
Detachment can be treated in the ophthalmology clinic with laser
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Visual acuity worse than 6/12
Visual field of < 10 degrees or less in the better eye
Visual field of < 20 degrees or less in the better eye
A and B are correct
A and C are correct
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UV exposure is strongly associated with subcapsular cataract
UV exposure is strongly associated with cortical cataract
Corticosteroid use is strongly associated with cortical cataract
There is a strong association between smoking and nuclear sclreos
Diabetes is strongly associated with cortical cataract
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Approximately 2% convert from dry to wet forms per year
Dry ARMD involves a choroidal neovascular membrane
Early ARMD causes distortion or scotoma of central vision
Wet ARMD involves gradual deterioration of the retinal pigment epithelium
Wet ARMD involves predominantly peripheral visual loss
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The Amsler grid helps to identify disease onset
Smoking increases the risk of ARMD 2 - 3 times
Dietary antioxidants have been shown to reduce risk
Zinc supplements have been shown to delay onset of ARMD
UV protection significantly reduces the risk of wet ARMD
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Asymmetrical presentation - dominant side usually more affected
Persistence of sweating even during sleep
Persistence of sweating beyond 6 months
Onset typically after the age of 25 years
Does not impair daily activities
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No investigations are necessary in typical cases
Thyroid functions tests are required in all cases
Full blood count and examination is required in all cases
Chest x-ray is required in all cases
B and C are both correct
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Small pits are often present on the nails beds
There is often a characteristic 'cheesy' smell
It is due to a fungal infection of the stratum corneum
It is due to infection with Mycobacterium sedentarius
It is unrelated to the diagnosis of palmoplantar hyperhidrosis
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