Esbl Introduction

4 Questions | Total Attempts: 78

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Definition Quizzes & Trivia

This quiz covers:a. the definition of extended spectrum antibioticsb. the definition of a beta lactamase inhibitorc. the names of the beta lactamase inhibitorsd. the definition of CLSI


Questions and Answers
  • 1. 
    A beta lactamase inhibitor functions by:
    • A. 

      Attaching to and neutralizing the beta lactamase enzyme.

    • B. 

      Changing the structure of the beta lactam antibiotic to which it is attached making it unrecognizable to the enzyme.

    • C. 

      Cleaving key bonds ultimately preventing it from effectively binding to the target.

    • D. 

      Offers an alternate site for the enzyme to attach reducing the enzymes overall effectiveness.

  • 2. 
    Of the three beta lactamase inhibitors listed, which is recommended for use in detecting extended spectrum beta lactamases.
    • A. 

      Clavulanic acid

    • B. 

      Tazobactam

    • C. 

      Sulbactam

  • 3. 
    To what do the initials CLSI refer?
  • 4. 
    Third generation cephalosporins and the monobactam aztreonam have a ringed structure which contains a sulfur ion.  These are hydrolyzed by extended spectrum beta lactamases.  Name this side chain.
    • A. 

      Clavulanate

    • B. 

      Oxyimino side ring

    • C. 

      Beta lactam ring