Egfrviii Mutation

4 Questions

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Family Quizzes & Trivia

This quiz is meant to test your comprehension of the EGFRvIII mutation.

Questions and Answers
  • 1. 
    EGFRvIII is
    • A. 

      Present in glioblastomas

    • B. 

      Sensitizes tumors to anti-EGFR therapies if PTEN is intact

    • C. 

      Sensitizes tumors to anti-EGFR therapies

    • D. 

      A and B

    • E. 

      A and C

  • 2. 
    EGFRvIII is amplified, overexpressed, and/or mutated in up to 40-50% of glioblastoma patients.
    • A. 


    • B. 


  • 3. 
    EGFRvIII is associated with
    • A. 

      A poor prognosis

    • B. 

      A favorable prognosis

  • 4. 
    EGFRvIII is used
    • A. 

      To assess a favorable clinical response to EGFR tyrosine kinase inhibitors

    • B. 

      As a molecular target in treatment

    • C. 

      For determining treatment decisions in patients with glioblastomas

    • D. 

      All of the above