CVS Test 12 August 2013

16 Questions | Total Attempts: 32

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CVS Test 12 August 2013

Questions and Answers
  • 1. 
    Which ONE of the following is not classed as an Atorvastatin landmark trial?
    • A. 

      TNT

    • B. 

      CARDS

    • C. 

      ASCOT-BPLA

    • D. 

      ASCOT-LLA

  • 2. 
    Atorvastatin at a dose of 10-20 mg/day has been shown to be effective and well-tolerated in patients with severe or familial hypercholesterolaemia.
    • A. 

      True

    • B. 

      False

  • 3. 
    Which ONE of the following was a primary end-point in the ASCOT-LLA trial?
    • A. 

      Nonfatal coronary heart disease

    • B. 

      Nonfatal myocardial infarction

    • C. 

      Stroke

    • D. 

      Coronary revascularisation

  • 4. 
    In the CARDS trial atorvastatin at a dose of 10 mg/day was shown to reduce the risk of the primary end-point of major cardiovascular events in diabetic patients by 37%.
    • A. 

      True

    • B. 

      False

  • 5. 
    The MIRACL study randomised patients who were hospitalised for acute coronary syndrome to receive atorvastatin 80 mg/day or placebo.
    • A. 

      True

    • B. 

      False

  • 6. 
    In the TNT trial, which recruited coronary heart disease patients with metabolic syndrome, the risk of major cardiovascular events was reduced by what percentage in patients randomised to atorvastatin 80 mg/day compared to atorvastatin 10 mg/day?
    • A. 

      16%

    • B. 

      19%

    • C. 

      24%

    • D. 

      29%

  • 7. 
    Combined data from 49 completed atorvastatin trials has shown that rhabdomyolysis occurs in approximately 1 in 22 727 patients.
    • A. 

      True

    • B. 

      False

  • 8. 
    Atorvastatin has a clinical trial database larger than that of any other statin and has been shown to reduce major cardiovascular events in both primary and secondary prevention, and in a broad range of patients.
    • A. 

      True

    • B. 

      False

  • 9. 
    The INTERHEART Africa study revealed that more premature acute myocardial infarctions were shown to occur in sub-Saharan Africa than in any of the other 52 countries taking part in the study.
    • A. 

      True

    • B. 

      False

  • 10. 
    According to the South African Dyslipidaemia Guideline Consensus Statement which of the following are considered to be very high risk patients who do not require cardiovascular risk scoring?
    • A. 

      Type 2 diabetics

    • B. 

      Those with familial hypercholesterolaemia

    • C. 

      Patients with established atherosclerotic disease such as coronary artery disease

    • D. 

      All of the above

  • 11. 
    According to the South African Dyslipidaemia Guideline Consensus Statement cardiovascular risk scoring is important in which of the following patients?
    • A. 

      Those with a BMI >30kg/m2 or a waist circumference >94 cm in men or 80 cm in women

    • B. 

      Patients with a history of smoking 20 cigarettes a day for 10 years

    • C. 

      Patients on antihypertensive medication.

    • D. 

      All of the above

  • 12. 
    According to the South African Dyslipidaemia Guideline Consensus Statement patients with auto-immune diseases such as rheumatoid arthritis, psoriasis and systemic lupus erythematosus do not require cardiovascular risk scoring.
    • A. 

      True

    • B. 

      False

  • 13. 
    The South African Dyslipidaemia Guideline Consensus Statement recommends a full lipogram be carried out in which of the following circumstances? Choose all that apply.
    • A. 

      Upon the initial diagnosis of dyslipidaemia

    • B. 

      At follow-up visits when low density lipoprotein cholesterol is know to be the only abnormality in the patient's lipid profile.

    • C. 

      In a young South African adult from the age of 20 onwards, at least once(to check for familial hypercholesterolaemia).

    • D. 

      None of the above

  • 14. 
    Which of the following can cause secondary dyslipidaemia? Choose all that apply.
    • A. 

      Antiretroviral medication

    • B. 

      Diabetes mellitus

    • C. 

      Liver disease

    • D. 

      Alcohol excess

  • 15. 
    According to the South African Dyslipidaemia Guideline Consensus Statement, what would be the recommended statin(s) and dose(s) in a patient with a starting low density lipoprotein cholesterol of 3.9 mmol/L and a goal of <1.8 mmol/L?
    • A. 

      Atorvastatin 80 mg or rosuvastatin 40 mg

    • B. 

      Atorvastatin 10 mg or rosuvastatin 5 mg

    • C. 

      Atorvastatin 40 mg or rosuvastatin 10 mg

    • D. 

      Any statin at the lowest dose

  • 16. 
    The updated Framingham cardiovascular disease risk tables, for men and women, are considered to be appropriate for estimating the 10 year risk of coronary heart disease in the South African population.
    • A. 

      True

    • B. 

      False

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