1.
In iron deficiency anemia there is
Correct Answer
A. Low hemoglobin level and it is microcytic anemia(small size of RBCs).
Explanation
Iron deficiency anemia is characterized by low hemoglobin levels and microcytic anemia, which refers to the small size of red blood cells. This is because iron is essential for the production of hemoglobin, the protein that carries oxygen in the blood. Without sufficient iron, the body is unable to produce enough hemoglobin, resulting in low levels and smaller red blood cells. This can lead to symptoms such as fatigue, weakness, and shortness of breath.
2.
Fate of iron released from hemoglobin during RBC phagocytosis can be
Correct Answer
C. Both a and b.
Explanation
During the process of RBC phagocytosis, iron is released from hemoglobin. This iron can have two fates: it can be stored in the liver in the form of ferritin, or it can be used in erythropoiesis to form new red blood cells in the bone marrow. Therefore, the correct answer is that the iron released from hemoglobin during RBC phagocytosis can have both of these fates.
3.
Lactoferrin role in iron Hemostasis is
Correct Answer
F. All of the above
Explanation
Lactoferrin plays multiple roles in iron hemostasis. It increases iron absorption, ensuring that the free-iron concentration remains within normal levels and prevents iron overload. It also has an anti-inflammatory role by down-regulating the production of interleukin-6 (IL-6), which is an inflammatory mediator. Additionally, lactoferrin inhibits hepcidin and promotes ferroportin action, facilitating the transport of iron from the intestine to the bloodstream. Therefore, all of the given options (A, B, and C) are correct.
4.
Transferrin and Ferroportin respectively are
Correct Answer
B. An iron carrier protein and a transmembrane protein, that exports iron from small intestin into blood stream
Explanation
Transferrin is an iron carrier protein that binds to iron and transports it in the blood. Ferroportin, on the other hand, is a transmembrane protein that is involved in the export of iron from the small intestine into the bloodstream. Therefore, the correct answer is that Transferrin is an iron carrier protein and Ferroportin is a transmembrane protein that exports iron from the small intestine into the blood stream.
5.
Ferritin and Hepcidin respectively are
Correct Answer
A. An iron storage protein and a negative regulator of Ferroportin
Explanation
Ferritin is an iron storage protein that helps store iron in the body. It binds to excess iron and stores it in a non-toxic form until it is needed. Hepcidin, on the other hand, is a negative regulator of Ferroportin. Ferroportin is a transmembrane protein that exports iron from cells into the bloodstream. Hepcidin binds to Ferroportin and causes its internalization and degradation, thus decreasing the export of iron from cells. Therefore, Ferritin and Hepcidin respectively act as an iron storage protein and a negative regulator of Ferroportin.
6.
Transferrin compared to Lactoferrin
Correct Answer
F. All of above except B
Explanation
Both transferrin and lactoferrin are glycoproteins and serve as iron carrier proteins. They both have the same affinity towards iron. However, lactoferrin has a higher affinity for iron compared to transferrin. Therefore, the correct answer is "All of the above except B" because all the statements mentioned are true except for the statement that both transferrin and lactoferrin have the same affinity towards iron.
7.
The normal prolactin fasting value is less than ……………………..
Correct Answer
A. 25-30 ng/ml
Explanation
The normal prolactin fasting value is typically less than 25-30 ng/ml. This means that in a fasting state, the normal level of prolactin in the blood is usually below this range.
8.
From the Signs and Symptoms of hyperprolactinemia
Correct Answer
E. All of the above.
Explanation
This question asks about the signs and symptoms of hyperprolactinemia. The given options include oligomenorrhea or amenorrhea, galactorrhea, vaginal dryness and decrease in bone mass, infertility, and decreased sex drive. The correct answer is "all of the above" because hyperprolactinemia can cause all of these symptoms. Oligomenorrhea or amenorrhea refers to irregular or absent menstrual periods, galactorrhea is the production of breast milk in a woman who is not breastfeeding, vaginal dryness and decrease in bone mass can occur due to hormonal imbalances, and infertility and decreased sex drive are common symptoms of hyperprolactinemia.
9.
………… from underlying causes of Hyperprolactenemia
Correct Answer
E. All of the above.
Explanation
Hyperprolactinemia is a condition characterized by elevated levels of prolactin hormone in the blood. Tumors on the pituitary gland can cause hyperprolactinemia by increasing the production of prolactin. Hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormones, can also lead to hyperprolactinemia. Empty sella syndrome, a rare condition where the pituitary gland becomes flattened and enlarged, can disrupt the normal regulation of prolactin and result in hyperprolactinemia. Therefore, all of the above options (tumors on the pituitary gland, hypothyroidism, and empty sella syndrome) can be underlying causes of hyperprolactinemia.
10.
………… are from serious side effects of OHSS
Correct Answer
E. All of the above.
Explanation
The given correct answer is "all of the above." This means that all of the symptoms mentioned in the options (severe and rapid increase in weight, severe abdominal pain, and shortness of breath) are potential serious side effects of OHSS (ovarian hyperstimulation syndrome).
11.
From strategies followed for prevention and treatment of OHSS are
Correct Answer
E. All of the above.
Explanation
The strategies followed for prevention and treatment of OHSS include reducing exposure to gonadotrophins, insulin-sensitizing agents, non-steroidal anti-inflammatory administration, and dopamine agonist administration (Cabergoline). Therefore, the correct answer is "All of the above."
12.
HCG(Human Chorionic Gonadotropin) results in OHSS due to an increase in
Correct Answer
E. All of the above.
Explanation
HCG (Human Chorionic Gonadotropin) can result in OHSS (Ovarian Hyperstimulation Syndrome) due to various mechanisms. It can lead to an increase in RAS (Renin-Angiotensin System) production, which can contribute to the development of OHSS. HCG can also stimulate the production of VEGF (Vascular Endothelial Growth Factor), which promotes the growth of new blood vessels and can increase capillary permeability. This increased permeability can lead to fluid accumulation and contribute to the development of OHSS. Additionally, HCG can induce angiogenesis, the formation of new blood vessels, which can also contribute to the development of OHSS. Therefore, all of the above mechanisms can play a role in causing OHSS when HCG is administered.
13.
Normal range of Albumin in urine.
Correct Answer
C. Less than 30mg.
Explanation
The normal range of albumin in urine is less than 30mg. This means that if the amount of albumin in the urine is less than 30mg, it is considered to be within the normal range. Any amount of albumin in the urine that is higher than 30mg may indicate a potential health issue.
14.
In Amino acid metabolism
Correct Answer
F. All of the above
Explanation
The given statement is correct because all of the statements mentioned are true. In amino acid metabolism, a transamination reaction is a reaction in which amino acids lose the NH3 group. The acceptor of the NH3 group is alpha-ketoglutarate. Transamination reactions are reversible, and when alpha-ketoglutarate accepts the NH3 group, it becomes glutamate. Amino acids contribute approximately 10 to 15% of the total energy in our body. Therefore, all of the above statements are true.
15.
Normal protein diet, low protein diet and very low protein diet are ………………. respectively
Correct Answer
B. 0.8 g/kg/day, 0.6 g/kg/day and 0.3 g/kg/day
Explanation
The correct answer is 0.8 g/kg/day, 0.6 g/kg/day and 0.3 g/kg/day. This means that a normal protein diet requires a daily intake of 0.8 grams of protein per kilogram of body weight, a low protein diet requires 0.6 grams of protein per kilogram of body weight, and a very low protein diet requires 0.3 grams of protein per kilogram of body weight.
16.
Flibanorin Active Ingredient is
Correct Answer
B. Flibanserin
Explanation
The correct answer is Flibanserin. Flibanserin is the active ingredient in Flibanorin.
17.
Flibanorin is indicated for
Correct Answer
B. Hypoactive Sexual Desire Disorder
Explanation
Flibanorin is indicated for Hypoactive Sexual Desire Disorder. This means that it is specifically prescribed to treat a condition in which a person experiences a persistent or recurrent lack of sexual fantasies or desire for sexual activity, causing distress or interpersonal difficulties. It is not indicated for female sexual disorder, male sexual disorder, or any other condition.
18.
Flibanorin improves women (SSE , FSDI ) only
Correct Answer
B. False
Explanation
Flibanorin does not improve women's SSE (sexual self-esteem) and FSDI (female sexual distress index) only. This statement implies that Flibanorin has other effects or benefits besides improving SSE and FSDI in women. Therefore, the correct answer is False.
19.
Flibanorin improves women is non - hormonal drug
Correct Answer
A. True
Explanation
Flibanorin is a non-hormonal drug that is known to improve women's conditions.
20.
Optaminess contains
Correct Answer
A. 9 essential amino acids + 1 non essential amino acids
Explanation
Optaminess contains 9 essential amino acids + 1 non-essential amino acid. Amino acids are the building blocks of proteins, and they can be classified as essential or non-essential based on whether the body can produce them or not. Essential amino acids cannot be synthesized by the body and must be obtained from the diet, while non-essential amino acids can be produced by the body itself. Optaminess provides all 9 essential amino acids that the body needs to obtain from external sources, along with an additional non-essential amino acid.
21.
Optaminess Pack is
Correct Answer
D. All of the above
Explanation
The Optaminess Pack is available in three different sizes: 100 tablets for 290 EGP, 150 tablets for 435 EGP, and 200 tablets for 580 EGP. Therefore, the correct answer is "All of the above" as it includes all the available options for purchasing the Optaminess Pack.
22.
Optaminess is a part of the conservative treatment of patients with Chronic Kidney Disease.
Correct Answer
A. True
Explanation
Optaminess is a part of the conservative treatment of patients with Chronic Kidney Disease. This means that it is indeed true that optaminess is included in the treatment plan for patients with this condition. Optaminess refers to the use of conservative measures such as lifestyle modifications, dietary changes, and medication management to slow down the progression of kidney disease and manage its symptoms. It is an important component of the overall care plan for patients with Chronic Kidney Disease.
23.
Optaminess dose is
Correct Answer
D. All of the above
Explanation
The correct answer is "All of the above". This means that the optimal dosage of Optaminess can vary depending on the weight of the patient and the type of diet they are on. For patients on a Low Protein Diet (LPD), the recommended dosage is 1 tablet per 10 kilograms of body weight per day. For patients on a Very Low Protein Diet (VLPD), the recommended dosage is 1 tablet per 5 kilograms of body weight per day. Additionally, for patients on a VLPD, the dosage can also be increased to 2 tablets per 10 kilograms of body weight per day. Therefore, all three options mentioned in the question are correct.
24.
Marvigoline therapeutic Class is Dopamine Agonist
Correct Answer
A. True
Explanation
Marvigoline belongs to the therapeutic class of dopamine agonists. Dopamine agonists are medications that mimic the effects of dopamine, a neurotransmitter in the brain. They are commonly used in the treatment of conditions such as Parkinson's disease and restless legs syndrome. Marvigoline, being a dopamine agonist, would also exert its therapeutic effects by interacting with dopamine receptors in the brain. Therefore, the statement that Marvigoline therapeutic class is dopamine agonist is true.
25.
Magnetrel is considered as
Correct Answer
C. ACEI/CCB
Explanation
Magnetrel is considered as ACEI/CCB because ACEI stands for Angiotensin-Converting Enzyme Inhibitor and CCB stands for Calcium Channel Blocker. Magnetrel is a combination medication that contains both an ACEI and a CCB. ACEIs work by blocking the enzyme that converts angiotensin I to angiotensin II, resulting in vasodilation and decreased blood pressure. CCBs work by blocking calcium channels in the blood vessels, causing relaxation of the smooth muscles and further reducing blood pressure. Therefore, Magnetrel is classified as an ACEI/CCB combination medication.
26.
Magnetrel is formulated as Tablets
Correct Answer
B. False
Explanation
The statement "Magnetrel is formulated as tablets" is false. This means that Magnetrel is not formulated as tablets. The formulation of Magnetrel may be in a different form, such as capsules, liquid, or powder.
27.
Benazepril binds to tissue with the highest affinity across ACEI with
Correct Answer
B. 27%
Explanation
Benazepril has a higher affinity for binding to tissue compared to other ACE inhibitors, with a binding affinity of 27%. This means that when benazepril is administered, it has a greater tendency to bind to tissue in the body. This affinity for tissue binding is important as it affects the drug's distribution, metabolism, and overall effectiveness in treating conditions such as hypertension.