Quiz: Can You Really Pass This Difficult Microbiology Test?

50 Questions

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Microbiology Quizzes & Trivia

There are a lot of quizzes that one can say are hard, but for sure this takes the cake. The quiz below is made up of some complex microbiology questions that most students have a difficult time tackling. Can you pass what is known as the difficult microbiology test ever? Why don’t you give it a shot and get to find out? All the best!


Questions and Answers
  • 1. 
    The condition in the host that results from pathogenic parasitic organism growing and multiplying within or on the host is called  
    • A. 

      An infection.

    • B. 

      An infectious disease.

    • C. 

      Pathogenesis

    • D. 

      All of these

  • 2. 
    • A. 

      the number of organisms present in or on the host. 


    • B. 

      The virulence of the organism.

    • C. 

      The host's defenses.

    • D. 

      all of the choices

  • 3. 
    Which of the following has no effect on the outcome of the host-parasite relationship?  
    • A. 

      The number of parasites on or in the host

    • B. 

      The virulence of the parasite 


    • C. 

      The defenses of the host

    • D. 

      All of these have an effect on the outcome of the host-parasite relationship.

  • 4. 
    Any organism that can cause disease in the host after direct interaction is a  
    • A. 

      Focal pathogen.

    • B. 

      Opportunistic pathogen.

    • C. 

      Primary pathogen. 


    • D. 

      secondary pathogen.

  • 5. 
     An __________ pathogen can cause disease in a host with impaired resistance.  
  • 6. 
    If a symbiont either harms or lives at the expense of another organism, the relationship is called  
    • A. 

      Symbiosis

    • B. 

      Parasitism

    • C. 

      Commensalisms

    • D. 

      Pathogenicity

  • 7. 
    An organism other than a human that is infected with a parasitic organism that can also infect humans is called a(n) ________ host.  
    • A. 

      Reservoir

    • B. 

      Endoparasite

    • C. 

      Transfer

    • D. 

      Intermediate

  • 8. 
    Which of the following is required of a pathogen to possess in order for it to be successful at causing infectious disease?  
    • A. 

      Initially be transported to the host

    • B. 

      Be able to exit the host

    • C. 

      Ability to adhere to, colonize, or invade the host

    • D. 

      Ability to damage the host 


    • E. 

      All of the choices

  • 9. 
    An inanimate object that may be contaminated with a pathogen is called a  
    • A. 

      Vector

    • B. 

      Fomite

    • C. 

      Zoonoses

    • D. 

      None of the choices

  • 10. 
    Which of the following is a facultative intracellular pathogen?  
    • A. 

      Viruses

    • B. 

      Brucella abortus

    • C. 

      Rickettsia

    • D. 

      All of the choices

  • 11. 
    Transfer of pathogens from host to environment and then to another host are said to be transmitted _________.  
  • 12. 
    A ________________ infection is a disease caused by a parasitic organism that is normally found in animals other than humans.  
  • 13. 
    The presence of viruses in the blood is called _______________.  
  • 14. 
    A __________ is an organism that transfers pathogens from one host to another.  
  • 15. 
    Vector-borne transmission can be either external or internal. In external (mechanical) transmission, the pathogen is carried  
    • A. 

      On a fomite.

    • B. 

      On the body surface of a vector.

    • C. 

      Within the vector.

    • D. 

      All of the choices

  • 16. 
    Inanimate materials involved in pathogen transmission are called reservoirs.  
    • A. 

      True

    • B. 

      False

  • 17. 
    Pathogens can penetrate to deeper tissues by producing specific virulence structures or enzymes.  These products include all of the following except  
    • A. 

      Collagenase

    • B. 

      Ribosomes

    • C. 

      Hyaluronidase

    • D. 

      Leukocidins

  • 18. 
    Bacteria within biofilms exchange  
    • A. 

      Plasmids

    • B. 

      Quorum-sensing molecules

    • C. 

      Nutrients

    • D. 

      All of the choices

  • 19. 
    Many types of bacteria are only _________ when dispersing from more stable and heterogeneous communities known as biofilms.  
  • 20. 
    Virulence may be measured experimentally at the host level by the __________ __________ __________, which measures the number of pathogens that kills 50% of an experimental group of hosts within a specified amount of time.  (3 words)  
  • 21. 
    The term __________ refers to the degree or intensity of pathogenicity.  
  • 22. 
     Because LPS is bound to the surface of bacteria, it is called a(n) __________.  
  • 23. 
    A neutralizing antibody against a toxin is called a(n) __________.  
  • 24. 
    Exotoxins can be denatured by iodine to form __________ which are useful in vaccines.  
  • 25. 
     The capacity of an organism to produce a toxin is called __________.  
  • 26. 
    Cholera toxin is an AB toxin.  
    • A. 

      True

    • B. 

      False

  • 27. 
     Many bacteria are pathogenic because they carry large segments of DNA called __________ _________, which were acquired by horizontal gene transfer, and which carry genes responsible for virulence.  (2 words)  
  • 28. 
    Once a pathogen has infected the host, __________________ is a measure of the pathogen's ability to spread to adjacent or other tissues.  
  • 29. 
     Gas gangrene caused by Clostridium perfringens results from disruption of cell membranes caused by production of ____________.  (2 words, 1 word)  
  • 30. 
    While exotoxin production is most generally associated with gram-positive bacteria, some Gram-negative bacteria also produce exotoxins.  
    • A. 

      True

    • B. 

      False

  • 31. 
    Macrophages are phagocytic cells.  
    • A. 

      True

    • B. 

      False

  • 32. 
    Fever response can be triggered by an endogenous pyrogen called interleukin-1.  
    • A. 

      True

    • B. 

      False

  • 33. 
    Colonization specifically refers to the multiplication of a pathogen on or within a host, and includes the resulting tissue invasion and damage.  
    • A. 

      True

    • B. 

      False

  • 34. 
    Generally, exotoxins tend to be more heat stable than endotoxins.  
    • A. 

      True

    • B. 

      False

  • 35. 
    The only organisms to produce endotoxins are gram-negative bacteria.  
    • A. 

      True

    • B. 

      False

  • 36. 
     Listeria monocytogenes propels itself through mammalian host cells using:  
    • A. 

      A modified form of gliding motility.


    • B. 

      Host cell actin and other cytoskeletal proteins.


    • C. 

      Periplasmic flagella.


    • D. 

      Fimbriae based twitching motility.

  • 37. 
    The toxic component of lipopolysaccharide is called  
    • A. 

      Lipid A.

    • B. 

      Exotoxin

    • C. 

      Hemolysin

    • D. 

      O antigen polysaccharide.

  • 38. 
     In the case of the AB toxins, the function of the B subunit is to  
    • A. 

      Act as a neurotoxin.

    • B. 

      Have enzyme activity that causes toxicity.

    • C. 

      act as a superantigen that stimulates T cells to release cytokines.

    • D. 

      bind to host cell receptor.

  • 39. 
    The characteristics of a pathogen that determine its virulence include which of the following?  
    • A. 

      Pathogenicity

    • B. 

      Invasiveness

    • C. 

      Infectivity

    • D. 

      All of the choices

  • 40. 
     Pathogenicity islands are typically associated with  
    • A. 

      Genes encoding tRNA.

    • B. 

      Genes encoding rRNA.

    • C. 

      G+C content similar to the rest of the bacterial genome. 


    • D. 

      None of the choices

  • 41. 
    Which of the following is not a biological effect associated with endotoxin?  
    • A. 

      Coagulation

    • B. 

      Paralysis

    • C. 

      Fever

    • D. 

      Fibrinolysis

  • 42. 
    Endotoxin is released when  
    • A. 

      gram negative pathogens lyse or divide. 


    • B. 

      Cells are starved for iron.

    • C. 

      cells are lysogenic for the beta phage.

    • D. 

      All of the choices

  • 43. 
    Which of the following is not a characteristic of lipid A?  
    • A. 

      heat stable

    • B. 

      toxic in nanogram amounts 


    • C. 

      Weakly immunogenic

    • D. 

      Neurotoxic

  • 44. 
    Endotoxins include which of the following?  
    • A. 

      Diphtheria toxin

    • B. 

      Lipopolysaccharide

    • C. 

      Tetanus toxin

    • D. 

      Botulinum toxin

  • 45. 
    Which of the following lyse erythrocytes to make iron available to pathogens?  
    • A. 

      Hyaluronidase

    • B. 

      Collagenase

    • C. 

      Hemolysins

    • D. 

      Coagulase

  • 46. 
    Adherence factors (adhesins) that play a role in infectious diseases caused by gram negative bacteria include all of the following except  
    • A. 

      Glycocalyx

    • B. 

      Fimbriae

    • C. 

      Lipoteichoic acid.

    • D. 

      Slime layer.

  • 47. 
     An infectious disease process caused by bacterial or fungal toxins in the blood is called  
    • A. 

      Septicemia

    • B. 

      Systemic

    • C. 

      Toxemia

    • D. 

      Phytogenic

  • 48. 
    By convention, when the word parasite is used without qualification, it often refers to  
    • A. 

      A protozoan or helminthic organism.

    • B. 

      Yeast or fungi.

    • C. 

      Bacteria or Archaea.


    • D. 

      Lichens