1.
Identify classes of OAD(Oral Anti-diabetic drug)required for controlling Insulin resistance in Diabetes management.
Correct Answer
B. Biguanide & Thiazolidindiones
Explanation
The correct answer is Biguanide & Thiazolidindiones. Biguanides, such as metformin, work by reducing glucose production in the liver and improving insulin sensitivity. Thiazolidindiones, such as pioglitazone, also improve insulin sensitivity by targeting specific receptors in the body. Both classes of drugs are commonly used to control insulin resistance in diabetes management.
2.
Identify correct treatment goals of diabetes according to ADA
Correct Answer
D. FPG(130 mg/dl);PPG(180mg/dl);HbA1c( 7%)
Explanation
The correct treatment goals for diabetes according to ADA are FPG (fasting plasma glucose) levels of 130 mg/dl, PPG (postprandial plasma glucose) levels of 180 mg/dl, and HbA1c (glycated hemoglobin) levels of 7%. These levels indicate good management and control of blood glucose levels, which is important in preventing complications associated with diabetes.
3.
At new onset of diabetes, contribution of PPG is approximately
Correct Answer
A. 30%
Explanation
At the new onset of diabetes, the contribution of postprandial glucose (PPG) is approximately 30%. This means that about 30% of the overall blood glucose levels in a person with newly diagnosed diabetes is due to the increase in blood sugar levels after meals. PPG is influenced by factors such as the type and amount of food consumed, insulin resistance, and insulin secretion. It is important to manage PPG levels to prevent complications and maintain good glycemic control in individuals with diabetes.
4.
Which is the macrovascular complication of diabetes?
Correct Answer
C. Cardiovascular disease
Explanation
Cardiovascular disease is a macrovascular complication of diabetes because it refers to a group of conditions that affect the heart and blood vessels. People with diabetes are at a higher risk of developing cardiovascular disease due to factors such as high blood sugar levels, high blood pressure, and abnormal cholesterol levels. These factors can lead to the buildup of plaque in the arteries, increasing the risk of heart attack, stroke, and other cardiovascular problems. Therefore, cardiovascular disease is considered a major complication of diabetes.
5.
What are the major symptoms of hypoglycemia?
Correct Answer
D. All
Explanation
The major symptoms of hypoglycemia include excess hunger, tachycardia, and depression. Hypoglycemia is a condition characterized by low blood sugar levels, which can lead to various symptoms. Excess hunger is a common symptom as the body tries to compensate for the low sugar levels. Tachycardia, or a rapid heartbeat, can occur as the body responds to the stress caused by low blood sugar. Depression can also be a symptom of hypoglycemia, as low blood sugar levels can affect mood and mental well-being. Therefore, all of the given options are correct symptoms of hypoglycemia.
6.
Identify correct dosage of gliclazide plain and SR.
Correct Answer
D. Gliclazide SR 60 mg OD & Gliclazide 80 mg BD
Explanation
The correct dosage of gliclazide plain and SR is Gliclazide SR 60 mg OD (once daily) and Gliclazide 80 mg BD (twice daily). This means that the extended-release form of gliclazide should be taken once a day, while the plain form should be taken twice a day.
7.
Gliclazide is Cardio-Safe because
Correct Answer
B. Exhibits beta cell SUR 1 specificity
Explanation
Gliclazide is Cardio-Safe because it exhibits beta cell SUR 1 specificity. This means that it specifically targets and acts on the SUR 1 receptors present on beta cells in the pancreas. By doing so, gliclazide helps to regulate and control blood sugar levels without affecting the contractility of the heart or increasing the cardiac workload. This specificity makes gliclazide a safe option for individuals with cardiovascular conditions who require diabetes medication.
8.
According to GUIDE study
Correct Answer
B. Gliclazide causes 50%lesser hypo event than glimepiride
Explanation
Gliclazide causes 50% fewer hypoglycemic events than glimepiride. This means that individuals taking gliclazide are less likely to experience episodes of low blood sugar compared to those taking glimepiride. Hypoglycemic events can be dangerous and have various symptoms, such as dizziness, confusion, and loss of consciousness. By causing 50% fewer hypo events, gliclazide is a safer option for managing diabetes and helps to prevent the potential complications associated with low blood sugar levels.
9.
According to nation-wide study on 1 lakh patients(Danish Study)
Correct Answer
A. Gliclazide is most cardio-safe among all SU
Explanation
The given answer states that Gliclazide is the most cardio-safe among all SU (Sulfonylurea) medications. This implies that among all the medications in the SU class, Gliclazide has the least risk of causing adverse cardiovascular events. It suggests that Gliclazide is a relatively safer option compared to other SU medications when considering cardiovascular safety.
10.
In ADVANCE study, what HbA1c goal was achieved with Gliclazide?
Correct Answer
D. 6%
Explanation
In the ADVANCE study, Gliclazide was able to achieve an HbA1c goal of 6%. This indicates that Gliclazide was effective in reducing blood glucose levels in the study participants.
11.
Dose titration with Dianorm OD is possible because
Correct Answer
D. All of above
Explanation
Dose titration with Dianorm OD is possible because the tablet is scored, meaning it can be easily divided into smaller doses. Additionally, Dianorm OD is formulated with HPMC technology, which allows for controlled release of the medication. The release profile of the full tablet is similar to that of the half tablet, ensuring consistent dosage even when the tablet is divided. Thus, all of the given statements explain why dose titration with Dianorm OD is possible.
12.
Which of below mentioned international body included Gliclazide in its essential medicine list?
Correct Answer
D. WHO
Explanation
The correct answer is WHO. The World Health Organization (WHO) included Gliclazide in its essential medicine list. This list consists of medications that are considered to be the most effective and safe for treating the most important health needs in a population. Gliclazide is an oral antidiabetic medication that helps to control blood sugar levels in people with type 2 diabetes. Its inclusion in the essential medicine list highlights its importance and effectiveness in managing this chronic condition.
13.
Identify the false statement
Correct Answer
D. Gliclazide is recommended for End Stage Renal Disease patients
14.
Which are the Brands of Dianorm Family launched first time in India?
Correct Answer
D. Both
Explanation
Both Dianorm-M and Dianorm-M-OD 1000 are the brands of the Dianorm Family that were launched first time in India.
15.
What is rationale of triple combination of Voglinorm GM ?
Correct Answer
D. All
Explanation
The rationale for the triple combination of Voglinorm GM is that it encompasses all the given options. The combination of drugs in Voglinorm GM likely has a complimentary mechanism of action, meaning that the drugs work together to provide a more effective treatment. Additionally, the combination may eliminate the need for a maximum dosage of any individual drug, making it easier to administer and potentially reducing side effects. Lastly, the inclusion of multiple drugs in a single combination pill may improve patient compliance by simplifying the medication regimen.
16.
AGI therapy in diabetic patients is recommended by
Correct Answer
B. AACE
Explanation
The correct answer is AACE. AGI therapy in diabetic patients is recommended by the American Association of Clinical Endocrinologists (AACE). The AACE provides guidelines and recommendations for the management of diabetes, including the use of AGI therapy. They base their recommendations on scientific evidence and expert consensus to ensure optimal care for diabetic patients.
17.
Voglinorm M is ideal for obese diabetic patients because
Correct Answer
C. It does not increase weight
Explanation
Voglinorm M is ideal for obese diabetic patients because it does not increase weight. This is important for obese patients as weight gain can worsen their condition and increase the risk of other health complications. By not causing weight gain, Voglinorm M allows obese diabetic patients to effectively manage their diabetes without the added concern of further weight gain.
18.
Gliclazide reduces 21% chances of nephropathy in Diabetic patients according to
Correct Answer
C. ADVANCE
Explanation
The correct answer is ADVANCE. The ADVANCE study found that gliclazide, a medication used to treat diabetes, reduced the chances of developing nephropathy (kidney disease) by 21% in diabetic patients. This study provides evidence that gliclazide can be effective in preventing nephropathy in this patient population.
19.
Which is the right combo for Diabetes management?
Correct Answer
B. Diet, exercise & correct medication
Explanation
The right combo for diabetes management is a combination of diet, exercise, and correct medication. This is because a balanced and healthy diet helps in controlling blood sugar levels, while regular exercise helps in maintaining a healthy weight and improving insulin sensitivity. Additionally, medication is often necessary to regulate blood sugar levels and manage the symptoms of diabetes. Therefore, all three components are crucial for effective diabetes management.
20.
Which of the following combinations is not available with Carsyon 2?
Correct Answer
A. Voglibose 0.2 mg+Glimepiride 1mg+Metformin 1000mg SR
Explanation
The correct answer is Voglibose 0.2 mg+Glimepiride 1mg+Metformin 1000mg SR. This combination is not available with Carsyon 2.