1.
What is the normal range of BP as per JNC 7
Correct Answer
A. 130/90
Explanation
According to JNC 7 (The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure), the normal range for blood pressure is considered to be 120/80. However, the given answer of 130/90 is incorrect as it falls within the range of hypertension stage 1.
2.
Uncontrolled hypertension can lead to which of the following
Correct Answer
C. Kidney failure
Explanation
Uncontrolled hypertension can lead to kidney failure. Hypertension, or high blood pressure, puts strain on the blood vessels throughout the body, including the kidneys. Over time, this can damage the blood vessels in the kidneys and impair their ability to filter waste and excess fluid from the body. If left untreated, uncontrolled hypertension can ultimately lead to kidney failure, where the kidneys are no longer able to function properly.
3.
Composition of Arbitel Trio
Correct Answer
B. Telmisartan 40 mg+ Cilnidipine 10mg+Metoprolol succcinate 25/50 mg (ER) Tablets
Explanation
The correct answer is Telmisartan 40 mg+ Cilnidipine 10mg+Metoprolol succcinate 25/50 mg (ER) Tablets. This combination of drugs is the composition of Arbitel Trio. It includes Telmisartan, which is an angiotensin II receptor blocker used for the treatment of hypertension. Cilnidipine is a calcium channel blocker that helps in reducing blood pressure. Metoprolol succinate is a beta-blocker used to treat high blood pressure and heart-related conditions. Together, these drugs work synergistically to control blood pressure and improve cardiovascular health.
4.
SPRINT Trial concludes
Correct Answer
C. Achieving target systolic blood pressure 120 mm Hg
Explanation
The correct answer is achieving a target systolic blood pressure of 120 mm Hg. The SPRINT Trial concluded on cardiometabolic mortality and went beyond the benefits of blood pressure. It specifically focused on achieving a target systolic blood pressure of 120 mm Hg and its impact on end-stage renal disease.
5.
Left ventricular hypertrophy
Correct Answer
A. Is a condition in which the muscle wall of heart's left pumping chamber becomes thickened
Explanation
Left ventricular hypertrophy is a condition in which the muscle wall of the heart's left pumping chamber becomes thickened. This thickening occurs as a response to increased workload on the heart, such as high blood pressure or aortic valve stenosis. The thickened muscle can impair the heart's ability to pump blood effectively, leading to symptoms such as shortness of breath, chest pain, and fatigue. Left ventricular hypertrophy is often diagnosed through imaging tests like echocardiography and can be managed through lifestyle changes, medications, and sometimes surgery.
6.
Myalgia
Correct Answer
D. Pain in a muscle or group of muscles.
Explanation
The term "myalgia" refers to pain in a muscle or group of muscles. The other options mentioned in the question, such as pain in the morning due to high blood pressure, sudden onset of pain, and pain in the heart, are not correct explanations for myalgia. Myalgia specifically refers to muscular pain and does not involve high blood pressure, sudden onset, or pain in the heart.
7.
Triglyceride levels Desirable level
Correct Answer
A. 150 mg/dl
Explanation
The desirable level for triglyceride levels is 150 mg/dl. This means that a person's triglyceride levels should ideally be around 150 mg/dl to be considered healthy. Higher levels of triglycerides can be associated with an increased risk of heart disease and other health issues. Therefore, maintaining triglyceride levels within the desirable range is important for overall health.
8.
World hypertension day
Correct Answer
B. 17-May
Explanation
World Hypertension Day is observed on 17th May every year. This day aims to raise awareness about high blood pressure and its prevention, control, and treatment. It is an initiative of the World Hypertension League and is supported by various organizations and individuals worldwide. By promoting education and awareness, World Hypertension Day encourages people to take control of their blood pressure levels and adopt a healthy lifestyle.
9.
Unstable angina
Correct Answer
A. Condition in which your heart doesn't get enough blood flow and oxygen
Explanation
Unstable angina is a condition where the heart does not receive an adequate supply of blood flow and oxygen. This can result in chest pain or discomfort, typically triggered by physical activity or emotional stress. Unlike stable angina, which is predictable and can be relieved by rest or medication, unstable angina is more severe and can occur even at rest. It is considered a medical emergency as it may be a sign of an impending heart attack. High triglyceride levels, on the other hand, refer to an elevated amount of fat in the blood and are not directly related to unstable angina.
10.
High Blood pressure leads to
Correct Answer
D. All the Above
Explanation
High blood pressure, also known as hypertension, can lead to various complications in different organs of the body. Nephropathy refers to kidney damage caused by high blood pressure, while retinopathy refers to damage to the blood vessels in the retina of the eye. Cardiomyopathy is a condition that affects the heart muscle. Since high blood pressure can cause damage to both the kidneys, eyes, and heart, the correct answer is "All the Above".
11.
Angiotensin II effects on hypothalamus
Correct Answer
D. Incease ADH secretion
Explanation
Angiotensin II is known to stimulate the release of antidiuretic hormone (ADH) from the hypothalamus. ADH helps regulate water balance in the body by increasing water reabsorption in the kidneys. This hormone acts on the collecting ducts in the kidneys, making them more permeable to water and reducing water loss through urine. Therefore, an increase in ADH secretion would result in increased water reabsorption and decreased urine output, helping to conserve water in the body.
12.
HOPE Trial related to
Correct Answer
B. RAMIPRIL
Explanation
The HOPE trial is related to RAMIPRIL. The trial was conducted to evaluate the effectiveness of RAMIPRIL in reducing cardiovascular events and mortality in high-risk patients. RAMIPRIL is an ACE inhibitor commonly used to treat high blood pressure and heart failure. The trial showed that RAMIPRIL significantly reduced the risk of heart attack, stroke, and death in patients with cardiovascular disease or diabetes. Therefore, RAMIPRIL is the correct answer in this context.
13.
White coat Hypertension
Correct Answer
B. Patient's feeling of anxiety in a medical environment results in an abnormally high blood preessure
Explanation
The correct answer is that the patient's feeling of anxiety in a medical environment results in an abnormally high blood pressure. This is known as white coat hypertension, where a person's blood pressure is elevated due to the stress or anxiety of being in a medical setting. This can lead to inaccurate readings and a misdiagnosis of hypertension.
14.
Echocardiography
Correct Answer
B. To create images of the heart
Explanation
Echocardiography is a test that is used to create images of the heart. It is a non-invasive procedure that uses sound waves to produce detailed images of the heart's structure and function. These images can help doctors diagnose and evaluate various heart conditions, such as heart valve problems, heart muscle abnormalities, and fluid buildup around the heart. By analyzing the images, healthcare professionals can assess the overall health of the heart and determine the best course of treatment for the patient.
15.
Clinidipine blocks
Correct Answer
A. L & N type Calcium channal
Explanation
Clinidipine is a calcium channel blocker that is used to treat hypertension. It specifically blocks L-type and N-type calcium channels. L-type calcium channels are found in cardiac and smooth muscle cells, and their blockade leads to vasodilation and decreased contractility of the heart. N-type calcium channels are found in the central nervous system and are involved in neurotransmitter release. Blocking these channels can reduce pain transmission and relieve symptoms of certain neurological disorders. Therefore, the correct answer is that clinidipine blocks both L-type and N-type calcium channels.
16.
Clopidegrol Mechanisam of action
Correct Answer
A. Inhibits the binding of adenosine diphosphate (ADP)
Explanation
The correct answer is "Inhibits the binding of adenosine diphosphate (ADP)". This means that Clopidegrol prevents ADP from binding to its receptor, which is important for platelet activation and aggregation. By inhibiting this binding, Clopidegrol reduces platelet aggregation and the formation of blood clots. This mechanism of action is well-established and has been shown to be effective in preventing cardiovascular events in patients at risk.
17.
Cells that release renin
Correct Answer
C. Juxtaglomerular cells
Explanation
Juxtaglomerular cells are specialized cells located in the kidney that release renin. Renin is an enzyme that plays a crucial role in the regulation of blood pressure and fluid balance in the body. These cells are located near the glomerulus, which is a part of the kidney involved in the filtration of blood. When there is a decrease in blood pressure or low sodium levels, juxtaglomerular cells release renin, which initiates a series of reactions leading to the production of angiotensin II, a potent vasoconstrictor. This helps to increase blood pressure and maintain fluid balance in the body.
18.
Beta cells present in
Correct Answer
A. Liver
Explanation
Beta cells are specialized cells found in the pancreas, not the liver. These cells are responsible for producing and releasing insulin, a hormone that helps regulate blood sugar levels. Insulin is crucial for the metabolism and storage of glucose in the body. While the liver does play a role in regulating blood sugar levels, it does not contain beta cells. Therefore, the correct answer is liver.
19.
Which of the following beta-blockers is beta-1 selective with vasodilatation?
Correct Answer
C. Metoprolol
Explanation
Metoprolol is a beta-blocker that is beta-1 selective, meaning it primarily targets beta-1 receptors in the body. It also has vasodilatory effects, which means it helps to relax and widen blood vessels, leading to a decrease in blood pressure. This combination of beta-1 selectivity and vasodilation makes metoprolol a commonly prescribed medication for conditions such as hypertension and heart failure. Propanolol, Carvedilol, and Atenolol are also beta-blockers, but they do not have the same level of beta-1 selectivity or vasodilatory effects as metoprolol.
20.
ACE present in
Correct Answer
A. Lung
Explanation
ACE (Angiotensin-converting enzyme) is primarily present in the lungs. It is an enzyme that converts angiotensin I to angiotensin II, which is a potent vasoconstrictor. ACE is crucial in regulating blood pressure and fluid balance in the body. While ACE can be found in other organs like the GI tract, brain, and eye, its highest concentration is in the lungs, where it plays a significant role in the renin-angiotensin-aldosterone system.
21.
Select the true statements.
Correct Answer
D. If you have 4 siblings and if two of them have hypertension, you need to pay more attention to health
Explanation
Having siblings with hypertension can be an indicator of a potential genetic predisposition to hypertension. Therefore, it is important to pay more attention to one's health in such a situation. However, it does not guarantee that the person will develop hypertension. Other factors such as lifestyle choices and overall health also play a significant role in the development of hypertension.
22.
What is the main dietry cause of high blood chloesterol
Correct Answer
C. Too much trans fat
Explanation
Trans fats are a type of unsaturated fat that can raise levels of bad cholesterol (LDL) and lower levels of good cholesterol (HDL) in the body. Consuming too much trans fat can lead to an increase in blood cholesterol levels, which can increase the risk of heart disease and other cardiovascular problems. Therefore, too much trans fat is the main dietary cause of high blood cholesterol.
23.
First-line agents used in treating congestive heart failure
Correct Answer
A. ACE inhibitors
Explanation
ACE inhibitors are first-line agents used in treating congestive heart failure. They work by blocking the action of an enzyme called angiotensin-converting enzyme (ACE), which is responsible for the production of a hormone called angiotensin II. Angiotensin II causes blood vessels to constrict and promotes the release of another hormone called aldosterone, which leads to fluid retention. By blocking ACE, ACE inhibitors help to relax blood vessels, reduce fluid retention, and improve the efficiency of the heart's pumping action. This makes them an effective choice for managing congestive heart failure.
24.
Risk factors for developing atrial fibrillation include:
Correct Answer
B. High blood pressue
Explanation
The correct answer is high blood pressure. High blood pressure is a known risk factor for developing atrial fibrillation. It can lead to changes in the structure and function of the heart, increasing the likelihood of developing abnormal heart rhythms such as atrial fibrillation. Overactive thyroid gland and excessive intake of alcohol can also contribute to atrial fibrillation, but they are not the only risk factors mentioned in the question.
25.
Chlorthalidone act on
Correct Answer
C. Distal convoluted tubule
Explanation
Chlorthalidone acts on the distal convoluted tubule. This is the part of the nephron in the kidney where final adjustments to the urine are made before it is excreted from the body. Chlorthalidone is a diuretic medication that works by inhibiting the reabsorption of sodium and chloride ions in the distal convoluted tubule, leading to increased excretion of water and electrolytes in the urine. By acting on this specific part of the nephron, chlorthalidone helps to reduce blood pressure and treat conditions such as hypertension and edema.