Cabig Architecture And Vcde Joint Workspace May 2009 Face-to-face Quiz Bowl 1

10 Questions | Total Attempts: 86

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Cabig Architecture And Vcde Joint Workspace May 2009 Face-to-face Quiz Bowl 1 - Quiz

This quiz bowl for the caBIG® Architecture and VCDE Joint Workspace May 2009 Face-to-Face Meeting will challenge your knowledge of bioinformatics and cancer.


Questions and Answers
  • 1. 
    Which of the following is false: Margaret Dayhoff  
    • A. 

      Initiated the collection of protein sequences in the Atlas of Protein Sequence and Structure.

    • B. 

      Developed the BLOSUM substitution matrix.

    • C. 

      Developed the one letter code for amino acids.

    • D. 

      Developed the PAM substitution matrix.

  • 2. 
    Which if the following does not make multiple sequence alignments:
    • A. 

      MUSCLE

    • B. 

      ClustalW

    • C. 

      MrBayes

    • D. 

      TCoffee

  • 3. 
    Which of the following algorithms was published first:
    • A. 

      The Needleman-Wunsch Algorithm

    • B. 

      The Smith-Waterman Algorithm

  • 4. 
    What does BLAST stand for?
    • A. 

      Biological Local Alignment Search Tool

    • B. 

      Basic Local Alignment Search Tool

    • C. 

      Basic Local Alignment System Tool

  • 5. 
    Which of the following is not a clustering algortihm?
    • A. 

      K-means

    • B. 

      Nearest neighbor

    • C. 

      Single Linkage

    • D. 

      Fuzzy c-means

    • E. 

      Next-door neighbor

  • 6. 
    Which database is older:
    • A. 

      Genbank

    • B. 

      Protein Data Bank (PDB)

  • 7. 
    What are the two commonly used colors for dyes in gene expression analysis?
    • A. 

      Red and green

    • B. 

      Yellow and blue

    • C. 

      Red and yellow

    • D. 

      Read and blue

  • 8. 
    Which paper is the most cited?
    • A. 

      T.F. Smith, M.S. Waterman, "Identification of common molecular subsequences," Journal of Molecular Biology, 147:195-7, 1981.

    • B. 

      S.F. Altschul et al., "Basic local alignment search tool," Journal of Molecular Biology, 215:403-10, 1990.

  • 9. 
    What was the first oncogene identified?
    • A. 

      Ras

    • B. 

      Src

    • C. 

      Myc

    • D. 

      Abl

  • 10. 
    What is the most common fatal cancer in men in 2009?
    • A. 

      Prostate

    • B. 

      Colon

    • C. 

      Lung

    • D. 

      Pancreas

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