Cabig Architecture And Vcde Joint Workspace May 2009 Face-to-face Quiz Bowl 1
This quiz bowl for the caBIG® Architecture and VCDE Joint Workspace May 2009 Face-to-Face Meeting will challenge your knowledge of bioinformatics and cancer.
- 1.Which of the following is false: Margaret Dayhoff
- A.
Initiated the collection of protein sequences in the Atlas of Protein Sequence and Structure.
- B.
Developed the BLOSUM substitution matrix.
- C.
Developed the one letter code for amino acids.
- D.
Developed the PAM substitution matrix.
- 2.Which if the following does not make multiple sequence alignments:
- A.
MUSCLE
- B.
ClustalW
- C.
MrBayes
- D.
TCoffee
- 3.Which of the following algorithms was published first:
- A.
The Needleman-Wunsch Algorithm
- B.
The Smith-Waterman Algorithm
- 4.What does BLAST stand for?
- A.
Biological Local Alignment Search Tool
- B.
Basic Local Alignment Search Tool
- C.
Basic Local Alignment System Tool
- 5.Which of the following is not a clustering algortihm?
- A.
K-means
- B.
Nearest neighbor
- C.
Single Linkage
- D.
Fuzzy c-means
- E.
Next-door neighbor
- 6.Which database is older:
- A.
Genbank
- B.
Protein Data Bank (PDB)
- 7.What are the two commonly used colors for dyes in gene expression analysis?
- A.
Red and green
- B.
Yellow and blue
- C.
Red and yellow
- D.
Read and blue
- 8.Which paper is the most cited?
- A.
T.F. Smith, M.S. Waterman, "Identification of common molecular subsequences," Journal of Molecular Biology, 147:195-7, 1981.
- B.
S.F. Altschul et al., "Basic local alignment search tool," Journal of Molecular Biology, 215:403-10, 1990.
- 9.What was the first oncogene identified?
- A.
Ras
- B.
Src
- C.
Myc
- D.
Abl
- 10.What is the most common fatal cancer in men in 2009?
- A.
Prostate
- B.
Colon
- C.
Lung
- D.
Pancreas
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