Block 2 Hematopoeisis

29 Questions

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Block 2 Hematopoeisis

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Questions and Answers
  • 1. 
    The leucocyte that contains the major basic protein is the
    • A. 

      Neutrophil

    • B. 

      Eosinophil

    • C. 

      Monocyte

    • D. 

      Lymphocyte

    • E. 

      Basophil

  • 2. 
    Which type of leukocyte is shown in the electron micrograph shown?
    • A. 

      Neutrophil

    • B. 

      Eosinophil

    • C. 

      Monocyte

    • D. 

      Lymphocyte

    • E. 

      Basophil

  • 3. 
    Which is the only leukocyte that, after entering the connective tissue from the bloodstream, can re-enter the bloodstream?
    • A. 

      Lymphocyte

    • B. 

      Neutrophil

    • C. 

      Monocyte

    • D. 

      Basophil

    • E. 

      Neutrophil

  • 4. 
    Which of the following hematopoetic cell types will the growth factor erythropoietin stimulate?
    • A. 

      CFU-Eo

    • B. 

      CFU-E

    • C. 

      CFU-GM

    • D. 

      CFU-GEMM

    • E. 

      CFU-B

  • 5. 
    Which of the following are abundant in bone marrow stroma?
    • A. 

      Skeletal muscle cells

    • B. 

      T lymphocytes

    • C. 

      Macrophages

    • D. 

      Smooth muscle cells

    • E. 

      Platelets

  • 6. 
    Hematopoeisis occurs in different places throughout life. Which of the following is responsible for Hematopoeisis during the fetal period?
    • A. 

      Yolk sac mesoderm

    • B. 

      Yolk sac endoderm

    • C. 

      Liver and spleen

    • D. 

      Kidney

    • E. 

      Bone marrow

  • 7. 
    Hematopoeisis occurs in different places throughout life. When does hematopoeisis primarily occur in the bone marrow?
    • A. 

      3rd-4th week of gestation

    • B. 

      5th week of gestation

    • C. 

      5th month of gestation

    • D. 

      After birth

  • 8. 
    Which of the following is MOST responsible for the color of yellow bone marrow?
    • A. 

      Adipose cells

    • B. 

      Megakaryocytes

    • C. 

      Thin-walled sinusoids

    • D. 

      Hematopoietic cells

    • E. 

      Macrophages

  • 9. 
    Which of the following DOES NOT contain red bone marrow?
    • A. 

      Sternum

    • B. 

      Lower half of sacrum

    • C. 

      Skull bones

    • D. 

      Ribs

    • E. 

      Vertebrae

  • 10. 
    Which of the following stages does mitosis INITIALLY disappear during neutrophil formation?
    • A. 

      Myeloblast

    • B. 

      Promyelocyte

    • C. 

      Neutrophilic myelocyte

    • D. 

      Neutrophilic metamyelocyte

    • E. 

      Band neutrophil

  • 11. 
    Which of the following is EXCLUSIVE to neutrophil formation concerning granulocytopoiesis?
    • A. 

      Myeloblast

    • B. 

      Promyelocyte

    • C. 

      Myelocyte

    • D. 

      Metamyelocyte

    • E. 

      Band form

  • 12. 
    Azurophilic granules occur first in ____________ during granulocyte formation.
    • A. 

      Myeloblast

    • B. 

      Promyelocyte

    • C. 

      Myelocyte

    • D. 

      Metamyelocyte

    • E. 

      Band form

  • 13. 
    • A. 

      Large number of young neutrophils

    • B. 

      Indication of bacterial infection

    • C. 

      Neutrophilia

    • D. 

      Increased chemotactic factors

    • E. 

      All of the above

  • 14. 
    Which of the following DOES NOT share the same progenitor?
    • A. 

      Monocyte, neutrophil

    • B. 

      Monocyte, lymphocyte

    • C. 

      Monocyte, mast cell

    • D. 

      Monocyte, macrophage

    • E. 

      Monocyte, osteoclast

  • 15. 
    Which of the following is capable of endomitosis?
    • A. 

      CFU-Meg

    • B. 

      Megakaryoblast

    • C. 

      Megakaryocytes

    • D. 

      Monoblast

    • E. 

      Monocytes

  • 16. 
    Which of the following is associated with Thrombocytopenic purpura?
    • A. 

      Megakaryocytes

    • B. 

      Monocytes

    • C. 

      Lymphocytes

    • D. 

      Neutrophils

    • E. 

      Eosinophils

    • F. 

      Basophils

  • 17. 
    Which of the following is the last stage in erythropoiesis that can undergo mitosis?
    • A. 

      Proerythroblast

    • B. 

      Basophilic erythroblast

    • C. 

      Polychromatophilic erythroblast

    • D. 

      Orothochromatophilic erythroblast (normoblast)

    • E. 

      Polychromatophilic erythrocyte (reticulocyte)

    • F. 

      Mature erythrocyte

  • 18. 
    Which of the following controls the amount of RBCs in circulation by secretion of erythropoietin?
    • A. 

      Kidney

    • B. 

      Spleen

    • C. 

      Liver

    • D. 

      Bone

    • E. 

      Thymus

  • 19. 
    Which of the following is an autoimmune disease related to low platelet count?
    • A. 

      Thrombocytopenic purpura

    • B. 

      Thrombocytopenia

    • C. 

      Both A and B

    • D. 

      None of the above

  • 20. 
    Which of the following is a positive marker for Helper T Cells and where are these cells found?
    • A. 

      CD4, cortex

    • B. 

      CD4, medulla

    • C. 

      CD8, cortex

    • D. 

      . CD8, medulla

    • E. 

      No markers, medulla

  • 21. 
    Which of the following is a positive marker for Cytotoxic T Cells and where are these cells found?
    • A. 

      CD4, cortex

    • B. 

      CD4, medulla

    • C. 

      CD8, cortex

    • D. 

      CD8, medulla

    • E. 

      No markers, medulla

  • 22. 
    • A. 

      Bone marrow

    • B. 

      Cortex of thyroid

    • C. 

      Medulla of thyroid

    • D. 

      Cortex of thymus

    • E. 

      Medulla of thymus

  • 23. 
    • A. 

      Bone marrow

    • B. 

      Cortex of thyroid

    • C. 

      Medulla of thyroid

    • D. 

      Cortex of thymus

    • E. 

      Medulla of thymus

  • 24. 
    Erythropoietin is a hormone that controls RBC count in circulation. Which of the following is NOT affected by erythropoietin?
    • A. 

      CFU-S

    • B. 

      CFU-E

    • C. 

      BFU-E

    • D. 

      Erythroblast

    • E. 

      Reticulocyte

  • 25. 
    Which of the following displays grey-blue cytoplasm with “cracked chromatin”?
    • A. 

      Proerythroblast

    • B. 

      Basophilic erythroblast

    • C. 

      Polychromatophilic erythroblast

    • D. 

      Orothochromatophilic erythroblast

    • E. 

      Polychromatophilic erythrocyte

    • F. 

      Mature erythrocyte

  • 26. 
    At which cell stage has the RBC lost its nucleus?
    • A. 

      Proerythroblast

    • B. 

      Basophilic erythroblast

    • C. 

      Polychromatophilic erythroblast

    • D. 

      Orothochromatophilic erythroblast

    • E. 

      Retiulocyte

    • F. 

      Mature erythrocyte

  • 27. 
    Which of the following displays an orange cytoplasm?
    • A. 

      Proerythroblast

    • B. 

      Basophilic erythroblast

    • C. 

      Polychromatophilic erythroblast

    • D. 

      Orothochromatophilic erythroblast

    • E. 

      Polychromatophilic erythrocyte

    • F. 

      Mature erythrocyte

  • 28. 
    Proerythroblasts have a ___________ cytoplasm?
    • A. 

      Acidophilic

    • B. 

      Basophilic

    • C. 

      Neutral

    • D. 

      Azurophilic

    • E. 

      See slide 25 Moore hematopoesis

  • 29. 
    The basophilia displayed in RBC precursor cells is primarily due to:
    • A. 

      Hemoglobin production

    • B. 

      RER

    • C. 

      Vesicular transport

    • D. 

      Lysosomes

    • E. 

      Golgi complex