Pharm Cardiovascular Drugs

11 Questions | Total Attempts: 260

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Pharm Cardiovascular Drugs

There are plenty of conditions that affect the most important organ in the body – the heart – and today we’re going to look at the pharmaceuticals used to treat one of the bigger issues you can come across, cardiovascular disease. What can you tell us about these drugs? Let’s find out.


Questions and Answers
  • 1. 
    A 62-year-old man is admitted to the emergency department in hypertensive crisis. Staff in the emergency department begin administration of an antihypertensive agent IV. The patient rapidly demonstrates adverse reactions to the drug, so staff treat these by IV administration of hydroxocobalamin. Which of the following is the antihypertensive agent that likely caused these adverse effects?
    • A. 

      Nitroglycerin

    • B. 

      Nitroprusside

    • C. 

      Fenoldopam

    • D. 

      Diazoxide

    • E. 

      Esmolol

  • 2. 
    A 56-year-old woman is admitted to the emergency department with acute pain in the pelvic region. Her current medication includes a diuretic. After examination, laboratory tests and imaging a diagnosis of calcium nephrolithiasis is made. Which of the following diuretics most likely contributes to the patient’s current symptoms?
    • A. 

      Dorzolamide

    • B. 

      Mannitol

    • C. 

      Ethacrynic acid

    • D. 

      Indapamide

    • E. 

      Furosemide

    • F. 

      Acetazolamide

  • 3. 
    A 45-year-old man goes to his doctor for a follow-up visit to discuss his raised high blood pressure revealed at recent routine checkup. The patient’s blood pressure is 154/95 mmHg and the doctor decides to initiate medication. One of the drugs prescribed by the doctor acts by blocking a specific receptor thereby causing a decrease in phospholipase C-mediated generation of IP3/DAG. Which of the following drugs is it likely to be?
    • A. 

      Fenoldopam

    • B. 

      Captopril

    • C. 

      Losartan

    • D. 

      Spironolactone

    • E. 

      Propranolol

  • 4. 
    A 72-year-old man is diagnosed with edema associated with heart failure. As part of his treatment regime his physician is considering the use of a diuretic. Which of the following diuretics would be contraindicated in this patient?
    • A. 

      Acetazolamide

    • B. 

      Mannitol

    • C. 

      Ethacrynic acid

    • D. 

      Furosemide

    • E. 

      Hydrochlorothiazide

  • 5. 
    A 54-year-old man has stage 2 hypertension for which he is treated as an outpatient with indapamide and enalapril as well as a third antihypertensive drug, with a different mechanism of action to the first two. One of the hemodynamic effects of this third drug is it does not change cardiac output. Which of the following is likely to be the third drug?
    • A. 

      Hydralazine

    • B. 

      Captopril

    • C. 

      Fenoldopam

    • D. 

      Diltiazem

    • E. 

      Propranolol

  • 6. 
    A 68-year-old African-American woman has Stage C heart failure which is poorly controlled by her current medication that consists of an ACE inhibitor, a diuretic and a beta blocker. Her doctor decides to change her medication regimen to improve her symptoms. Which of the following would be an appropriate alteration to her drug regimen?
    • A. 

      Add dobutamine to the current drugs

    • B. 

      Replace the beta blocker with milrinone

    • C. 

      Remove the diuretic

    • D. 

      Add hydralazine and isosorbide mononitrate to the current drugs

    • E. 

      Add verapamil to the current drugs

  • 7. 
    Which of the following antihypersensitive agents indirectly stimulates adrenoceptors via its actions as a false neurotransmitter?
    • A. 

      Methyldopa

    • B. 

      Prazosin

    • C. 

      Esmolol

    • D. 

      Hydralazine

    • E. 

      Clonidine

  • 8. 
    Which of the following drugs produces its diuretic action by direct inhibition of epithelial Na+ channels (ENaC) in the late distal tubule and the cortical collecting tubule, and also undergoes significant biotransformation prior to excretion?
    • A. 

      Acetazolamide

    • B. 

      Amiloride

    • C. 

      Conivaptan

    • D. 

      Ethacrynic acid

    • E. 

      Indapamide

    • F. 

      Mannitol

    • G. 

      Spironolactone

    • H. 

      Triamterene

  • 9. 
    A 47-year-old man visits his family physician on a follow-up appointment. After series of recent visits his blood pressure readings indicated to his physician that the patient was prehypertensive. Despite lifestyle modifications the patient’s blood pressure on this visit is recorded as 162/95 mmHg. He has a history of coronary artery disease and gastroesophageal reflux disease. Which of the following drugs is likely chosen to treat this patient’s hypertension?
    • A. 

      Minoxidil

    • B. 

      Enalapril

    • C. 

      Hydrochlorothiazide

    • D. 

      Verapamil

    • E. 

      Diltiazem

  • 10. 
    A variety of adrenergic drugs can be used in the treatment of hypertension. Which of the following acts primarily as a selective blocker of beta1 adrenoceptors?
    • A. 

      Methyldopa

    • B. 

      Labetalol

    • C. 

      Propranolol

    • D. 

      Prazosin

    • E. 

      Esmolol

  • 11. 
    A 47-year-old man visits his family doctor for a follow up appointment. His doctor discusses his recent blood tests which show total cholesterol and triglyceride levels of 310 mg/dL and 140 mg/dL, respectively. The patient does not require lifestyle modifications so a drug therapy is initiated with an antihyperlipidemic agent that indirectly causes an increase in hepatic bile-acid synthesis. Which of the following drugs is prescribed to the patient?
    • A. 

      Cholestyramine

    • B. 

      Niacin

    • C. 

      Gemfibrozil

    • D. 

      Ezetimibe

    • E. 

      Lovastatin