Micro Oncogenic Viruses

7 Questions | By Chachelly | Last updated: Nov 27, 2018 | Total Attempts: 684

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In this medical quiz we’ll be looking at micro oncogenic viruses, which are often attributed to the development of tumours by those who contract them. What can you tell us about how these viruses work and develop overtime? Take the quiz and find out now! Good luck!

Questions and Answers

1.

HTLV-1/2 encodes an enzyme called reverse transcriptase. The function of the reverse transcriptase enzyme is
- A.
  
  DNase activity
- B.
  
  RNA-dependent DNA polymerase activity
- C.
  
  DNA-dependent RNA polymerase activity
- D.
  
  RNA-dependent RNA polymerase activity
- E.
  
  Topoisomerase activity
2.

Cancer viruses are classified in several virus families. The following virus family contains a human cancer virus with an RNA genome
- A.
  
  Adenoviridae
- B.
  
  Herpesviridae
- C.
  
  Hepadnaviridae
- D.
  
  Papillomaviridae
- E.
  
  Flaviviridae
3.

A virus that causes human cancer is also associated with a nervous system disorder called tropical spastic paraparesis. That virus is
- A.
  
  Polyomavirus JC
- B.
  
  Polyomavirus SV40
- C.
  
  Herpes simplex virus
- D.
  
  Human T-lymphotropic virus
- E.
  
  Human immunodeficiency virus
4.

Viruses are contributing factors in
- A.
  
  50% of human cancers
- B.
  
  20% of human cancers
- C.
  
  40% of human cancers
- D.
  
  All cases of human cancers
5.

All or part of the virus genome persists in a transformed cell. The viral genome might be either integrated or persist in the cell as episome. Episomes are:
- A.
  
  Replicating linear elements composed of DNA
- B.
  
  Replicating circular extrachomosomal elements
- C.
  
  Replicatiung linear extrachromosomal elements composed of RNA
- D.
  
  Circular genomic elements that will eventually degrade
- E.
  
  Replicating genomic elements that switch between circular and linear elements
6.

E6 proteins from human papillomaviruses induce cell transformation by:
- A.
  
  Increasing the expression of p53
- B.
  
  Inhibiting Rb-mediated apoptosis
- C.
  
  Repressing the transcription of the inhibitory form of the Rb protein
- D.
  
  Disrupting Rb-E2f complexes
- E.
  
  Targeting the p53 protein for proteasomal degradation
- F.
  
  Inducing underphosphorylation of p53
7.

Which viruses are responsible for cell transformation due to integration of proviruses in the vicinity of proto-oncogenes (nontransducing viruses)?
- A.
  
  Adenoviruses
- B.
  
  Hepadnaviruses (Hepatitis B Virus)
- C.
  
  Papillomaviruses
- D.
  
  Herpesviruses
- E.
  
  Retroviruses