Biochem Biosignaling 2
Helpful quiz for biochem. This topic is biosignaling. 20 questions
- 1.Which of the following is a repector that signals via Gq?
- A.
Alpha 2 receptors
- B.
Beta receptors
- C.
M3 receptors
- D.
M4 receptors
- 2.PIP2 is cleaved into what?
- A.
IP3 and DAG
- B.
IP3 and NO
- C.
Calcium and DAG
- D.
NO and DAG
- 3.What enzyme is actived by the Gq alpha subunit?
- A.
Guanylate cyclase
- B.
Protein kinase C
- C.
ATPase
- D.
Phospholipase C-beta
- 4.Which of the following is an ubiquitous calcium binding cellular protein?
- A.
Diacyl glycerol
- B.
SOS
- C.
Calmodulin
- D.
None of the above
- 5.What are CAM kinases activated by?
- A.
Ca calmodulin complex
- B.
Na calmodulin complex
- C.
S calmodulin complex
- D.
N calmodulin complex
- 6.What actives protein kinase C (PKC)?
- A.
IP3 and calcium
- B.
IP3 and DAG
- C.
Phospholipase C-beta
- D.
DAG and calcium
- 7.When catalytic domains phosphorylate each other it is called?
- A.
Tyrosine kinase
- B.
Autophosphorylation
- C.
Proliferation
- D.
None of the above
- 8.Upon activation what substrate protein will a insulin receptor phosphorylate?
- A.
IRS-1
- B.
Grb2
- C.
SOS
- D.
Ras
- 9.What binds the phosphotyrosine residue on IRS-1 and recruits SOS?
- A.
MEK
- B.
Grb2
- C.
Raf-1
- D.
Ras
- 10.Which of the following is a GTP exchange protein (GEP)?
- A.
IRS-1
- B.
Grb2
- C.
SOS
- D.
Ras
- 11.Whcih of the following is a monomeric G protein and when it is active stimulates Raf-1
- A.
IRS-1
- B.
Grb2
- C.
SOS
- D.
Ras
- 12.Where is erythropoietin mainly produced?
- A.
Liver
- B.
Kidney
- C.
Pancreas
- D.
Gonads
- 13.A deficiency of erythropoietin may lead to?
- A.
Agina pectoris
- B.
Diabetes mellitus
- C.
Anemia
- D.
Diabetes insipidus
- 14.What type of activity does natriuretic factor receptors have on their catalytic domains?
- A.
Adenylyl cyclase enzyme activity
- B.
Guanylyl cyclase enzyme activity
- C.
Phospholipase C- beta enzyme activity
- D.
Phosphodiesterase enzyme activity
- 15.What converts GTP into cGMP?
- A.
Guanylyl cyclase
- B.
Adenylyl cyclase
- C.
Nitric oxide synthase
- D.
Phospholipase C-beta
- 16.What neurotransmitter is released at the the parasympathetic end?
- A.
Epinephrine
- B.
Norepinephrine
- C.
Acetylcholine
- D.
None of the above
- 17.What converts arginine into citruline and nitric oxide?
- A.
Guandylyl cylase
- B.
Adenylyl cyclase
- C.
Nitric oxide synthase
- D.
Phospholipase C-beta
- 18.What are compounds that release nitric oxde helpful in treating?
- A.
Agina pectoris
- B.
ED
- C.
Amemia
- D.
A and B
- 19.Which of the following is a type-V phosphodiesterase inhibitor?
- A.
Bactrim
- B.
Sildenafil
- C.
Eyrthromycin
- D.
Tetracycline
- 20.Nitric oxide was once known as?
- A.
Only nitric oxide
- B.
NO
- C.
Endothelial-derived relaxing factor
- D.
Vascular relaxing factor
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