Biochem Biosignaling 2

20 Questions | By Pharmdnate | Last updated: Jan 22, 2013

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Helpful quiz for biochem. This topic is biosignaling. 20 questions

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Questions and Answers

1.

Which of the following is a repector that signals via Gq?
- A.
  
  Alpha 2 receptors
- B.
  
  Beta receptors
- C.
  
  M3 receptors
- D.
  
  M4 receptors
2.

PIP2 is cleaved into what?
- A.
  
  IP3 and DAG
- B.
  
  IP3 and NO
- C.
  
  Calcium and DAG
- D.
  
  NO and DAG
3.

What enzyme is actived by the Gq alpha subunit?

Discuss
- A.
  
  Guanylate cyclase
- B.
  
  Protein kinase C
- C.
  
  ATPase
- D.
  
  Phospholipase C-beta
4.

Which of the following is an ubiquitous calcium binding cellular protein?
- A.
  
  Diacyl glycerol
- B.
  
  SOS
- C.
  
  Calmodulin
- D.
  
  None of the above
5.

What are CAM kinases activated by?

Discuss
- A.
  
  Ca calmodulin complex
- B.
  
  Na calmodulin complex
- C.
  
  S calmodulin complex
- D.
  
  N calmodulin complex
6.

What actives protein kinase C (PKC)?

Discuss
- A.
  
  IP3 and calcium
- B.
  
  IP3 and DAG
- C.
  
  Phospholipase C-beta
- D.
  
  DAG and calcium
7.

When catalytic domains phosphorylate each other it is called?

Discuss
- A.
  
  Tyrosine kinase
- B.
  
  Autophosphorylation
- C.
  
  Proliferation
- D.
  
  None of the above
8.

Upon activation what substrate protein will a insulin receptor phosphorylate?
- A.
  
  IRS-1
- B.
  
  Grb2
- C.
  
  SOS
- D.
  
  Ras
9.

What binds the phosphotyrosine residue on IRS-1 and recruits SOS?

Discuss
- A.
  
  MEK
- B.
  
  Grb2
- C.
  
  Raf-1
- D.
  
  Ras
10.

Which of the following is a GTP exchange protein (GEP)?
- A.
  
  IRS-1
- B.
  
  Grb2
- C.
  
  SOS
- D.
  
  Ras
11.

Whcih of the following is a monomeric G protein and when it is active stimulates Raf-1
- A.
  
  IRS-1
- B.
  
  Grb2
- C.
  
  SOS
- D.
  
  Ras
12.

Where is erythropoietin mainly produced?

Discuss
- A.
  
  Liver
- B.
  
  Kidney
- C.
  
  Pancreas
- D.
  
  Gonads
13.

A deficiency of erythropoietin may lead to?
- A.
  
  Agina pectoris
- B.
  
  Diabetes mellitus
- C.
  
  Anemia
- D.
  
  Diabetes insipidus
14.

What type of activity does natriuretic factor receptors have on their catalytic domains?

Discuss
- A.
  
  Adenylyl cyclase enzyme activity
- B.
  
  Guanylyl cyclase enzyme activity
- C.
  
  Phospholipase C- beta enzyme activity
- D.
  
  Phosphodiesterase enzyme activity
15.

What converts GTP into cGMP?

Discuss
- A.
  
  Guanylyl cyclase
- B.
  
  Adenylyl cyclase
- C.
  
  Nitric oxide synthase
- D.
  
  Phospholipase C-beta
16.

What neurotransmitter is released at the the parasympathetic end?

Discuss
- A.
  
  Epinephrine
- B.
  
  Norepinephrine
- C.
  
  Acetylcholine
- D.
  
  None of the above
17.

What converts arginine into citruline and nitric oxide?

Discuss
- A.
  
  Guandylyl cylase
- B.
  
  Adenylyl cyclase
- C.
  
  Nitric oxide synthase
- D.
  
  Phospholipase C-beta
18.

What are compounds that release nitric oxde helpful in treating?
- A.
  
  Agina pectoris
- B.
  
  ED
- C.
  
  Amemia
- D.
  
  A and B
19.

Which of the following is a type-V phosphodiesterase inhibitor?
- A.
  
  Bactrim
- B.
  
  Sildenafil
- C.
  
  Eyrthromycin
- D.
  
  Tetracycline
20.

Nitric oxide was once known as?
- A.
  
  Only nitric oxide
- B.
  
  NO
- C.
  
  Endothelial-derived relaxing factor
- D.
  
  Vascular relaxing factor

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