Biochem Biosignaling

20 Questions

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Biochemistry Quizzes & Trivia

Quiz to help study for biochem exams. This topic is biosignaling. 20 questions.


Questions and Answers
  • 1. 
    What messenger molcules do permeate the plasma membrane?
    • A. 

      Amines

    • B. 

      Steroids

    • C. 

      Proteins

    • D. 

      Peptides

  • 2. 
    Messenger molecules that do not permeate the plasma membrane bind to what type of receptors to make intracellular messengers?
    • A. 

      Cell surface receptors

    • B. 

      Intracellular nuclear receptors

    • C. 

      Trimeric receptors

    • D. 

      None of the above

  • 3. 
    What receptors do hydrophobic messengers bind?
    • A. 

      Cell surface receptors

    • B. 

      Trimeric receptors

    • C. 

      Intracellular nuclear receptors

    • D. 

      None of the above

  • 4. 
    In G-protein coupled receptors what subunit binds to GTP and has GTPase activity?
    • A. 

      Alpha

    • B. 

      Beta

    • C. 

      Gamma

    • D. 

      Delta

  • 5. 
    What type of receptors are beta adrenergic?
    • A. 

      Go coupled receptors

    • B. 

      Gt coupled receptors

    • C. 

      Gi coupled receptors

    • D. 

      Gs coupled receptors

  • 6. 
    All G-protein coupled receptors are?
    • A. 

      1 membrane-spanning receptors

    • B. 

      5 membrane-spanning receptors

    • C. 

      7 membrane-spanning receptors

    • D. 

      10 membrane-spanning receptors

  • 7. 
    • A. 

      ATPase

    • B. 

      Cyclic nucleotide phosphodiesterase

    • C. 

      Adenylate cyclase

    • D. 

      All of the above

  • 8. 
    Protein kinase A consist of what?
    • A. 

      1 catalytic subunit and 1 regulatory subunit

    • B. 

      1 catalytic subunit and 2 regulatory subunit

    • C. 

      2 catalytic subunit and 1 regulatory subunit

    • D. 

      2 catalytic subunit and 2 regulatory subunit

  • 9. 
    What type of kinase is PKA? (This causes phosphorylation of proteins by transferring the phosphate from ATP.)
    • A. 

      Ser-Thr protein kinase

    • B. 

      Gly-Ala protein kinase

    • C. 

      Val-Leu protein kinase

    • D. 

      None of the above

  • 10. 
    What converts cAMP to AMP?
    • A. 

      Adenylate cyclase

    • B. 

      Cyclic nucleotide phosphodiesterase

    • C. 

      ATPase

    • D. 

      GTPase

  • 11. 
    What receptors signal via Gi to inhibit adenylate cyclase?
    • A. 

      Alpha 2 receptors

    • B. 

      M2 receptors

    • C. 

      M4 receptors

    • D. 

      All of the above

  • 12. 
    What will happen to the number of intercellular cAMP as a result of stimulation of Gi coupled receptors?
    • A. 

      They will increase

    • B. 

      They will decrease

    • C. 

      They will remain the same

    • D. 

      They may increase or decrease

  • 13. 
    What convalently inactivates GTPase activity of Gs?
    • A. 

      ADP ribosylation by choleratoxin

    • B. 

      ADP ribosylation by pertussis toxin

    • C. 

      Phosphorylation by choleratoxin

    • D. 

      Phosphorylation by pertussis toxin

  • 14. 
    What inhibits Gi?
    • A. 

      ADP ribosylation by choleratoxin

    • B. 

      ADP ribosylation by pertussis toxin

    • C. 

      Phosphorylation by choleratoxin

    • D. 

      Phosphorylation by pertussis toxin

  • 15. 
    What inhibits Go?
    • A. 

      ADP ribosylation by choleratoxin

    • B. 

      ADP ribosylation by pertussis toxin

    • C. 

      Phosphorylation by choleratoxin

    • D. 

      Phosphorylation by pertussis toxin

  • 16. 
    What causes the phosphorylation of stimulated beta adrenergic receptors on the cytosolic side?
    • A. 

      Phosphorylase kinase

    • B. 

      ADP ribosylation by choleratoxin

    • C. 

      Beta receptor kinase

    • D. 

      All of the above

  • 17. 
    What does the phosphorylated beta receptor become bound to resulting in the internalization of the receptor by endocytosis?
    • A. 

      This does not occur

    • B. 

      Endocytosis happens by itself

    • C. 

      Alpha arrestin

    • D. 

      Beta arrestin

  • 18. 
    Molecules that binds a receptor is called?
    • A. 

      Ligands

    • B. 

      Binders

    • C. 

      Kinase

    • D. 

      None of the above

  • 19. 
    How is the G alpha subunit inactivated?
    • A. 

      GDP becomes hydrolyzed to GTP and Pi

    • B. 

      ADP becomes hydrolyzed to ATP and Pi

    • C. 

      GTP becomes hydrolyzed to GDP and Pi

    • D. 

      ATP becomes hydrolyzed to ADP and Pi

  • 20. 
    What is a G-protein coupled receptor pathway?
    • A. 

      Gs coupled adenylate cyclase pathway

    • B. 

      Gq coupled PIP2 pathway

    • C. 

      Gi and Go coupled pathway

    • D. 

      All of the above