Trivia Questions About Bacteriology

28 Questions | Total Attempts: 56

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Bacteriology Quizzes & Trivia

Questions and Answers
  • 1. 
    These diseases are commonly point or continuous source outbreaks
    • A. 

      Typhoid

    • B. 

      Whooping Cough

    • C. 

      Botulism

    • D. 

      Legionnaires Disease

    • E. 

      Staphylococcus aureus food poisoning

  • 2. 
    Genomes of bacterial pathogens have about 400 genes
    • A. 

      True

    • B. 

      False

  • 3. 
    Clostridium tetani is an obligate aerobe
    • A. 

      True

    • B. 

      False

  • 4. 
    Bacterial binary fission follows genome replication and meiosis
    • A. 

      True

    • B. 

      False

  • 5. 
    DNA transfer by transduction  requires contact between bacteria
    • A. 

      True

    • B. 

      False

  • 6. 
    Salmonella cells are typically 10um long
    • A. 

      True

    • B. 

      False

  • 7. 
    Cholera Toxin
    • A. 

      ADP-ribosylates translation elongation factor 2 (EF-2)

    • B. 

      Is a homologue of host adenylate cyclase

    • C. 

      Disrupts control of host adenylate cyclase activity

    • D. 

      Causes electrolyte loss into the lumen

    • E. 

      Causes a low volume bloody diarrhoea

  • 8. 
    These are typically zoonotic infections
    • A. 

      Cholera

    • B. 

      Dysentery

    • C. 

      Salmonellosis

    • D. 

      Typhoid

    • E. 

      EHEC 0157 diarrhoeal disease

  • 9. 
    These bacteria typically cause chronic disease
    • A. 

      Mycobacterium tuberculosis

    • B. 

      Treponema pallidum

    • C. 

      Bordetella pertussis

    • D. 

      Vibrio Cholera

    • E. 

      Helicobacter pylori

  • 10. 
    Endotoxin
    • A. 

      Is actively secreted by bacteria

    • B. 

      Is a component of capsule polysaccharide

    • C. 

      Activates macrophages via CD14

    • D. 

      Is an important defence against antibodies

    • E. 

      Is located in the Gram negative cell outer membrane

  • 11. 
    In tuberculosis
    • A. 

      Mycobacterium tuberculosis is protected by aligate polysaccharide

    • B. 

      Caseous necrosis is caused by a secreted exotoxin

    • C. 

      Immunity is established by a strong Th2 response

    • D. 

      Inflammation causes formation of a pseudomembrane in the airway

    • E. 

      Protection is afforded by the live BCG vaccine

  • 12. 
    Bacteria may evade the host defences by,
    • A. 

      Subverting macrophage function

    • B. 

      Avoiding phagocytosis

    • C. 

      Integrating into the host genome

    • D. 

      Destroying antibody

    • E. 

      Phase variation

  • 13. 
    The following have both inner and outer cell membranes
    • A. 

      Escherichia coli

    • B. 

      Streptococcus pyogenes

    • C. 

      Clostridium tetani

    • D. 

      Pseudomonas aeruginosa

    • E. 

      Neisseria meningitidis

  • 14. 
    Tetanus toxin
    • A. 

      Is produced by Clostridium tetani spores

    • B. 

      Cleaves small GTPases involved in signal transduction

    • C. 

      Is an adenylate cyclase, inactivating synaptobrevin

    • D. 

      Blocks release of stimulatory neurotransmitters in peripheral nerves

    • E. 

      Causes spastic paralysis

  • 15. 
    Streptococcus pyogenes
    • A. 

      Lancefield grouping is based on the cell surface M protein

    • B. 

      Is B-haemolytic and forms clusters of gram-positive cells

    • C. 

      Causes many acute suppurative infections and fasciitis

    • D. 

      Causes pneumonia, a common immediate causes of death

    • E. 

      Antigen-antibody complexes cause post-infection glomerulonephritis

  • 16. 
    These diseases are spread by propagated outbreaks
    • A. 

      Pneumonic plague

    • B. 

      Tuberculosis

    • C. 

      Legionnaires disease

    • D. 

      Botulism

    • E. 

      Dysentery

  • 17. 
    In tuberculosis
    • A. 

      M. tuberculosis is spread by small droplets and ingested by alveolar macrophages

    • B. 

      Acute inflammatory disease is resolved by a strong antibody response

    • C. 

      Caseous necrosis results from damage to the lungs by a bacterial exotoxin

    • D. 

      Protection is afforded by a toxoid vaccine

    • E. 

      A positive tuberculin skin test reflects a T cell response to mycobacterial components

  • 18. 
    The following cause zoonotic diseases of the GI tract
    • A. 

      Vibrio cholerae

    • B. 

      Salmonella enteriditis

    • C. 

      Salmonella typhi

    • D. 

      Shigella dystenteriae

    • E. 

      E.coli 0157

  • 19. 
    E. coli
    • A. 

      Genomes contain 300-500 genes depending on the type of pathogenicity island

    • B. 

      Is a facultative anaerobe, generating ATP from mitochondria during aerobic growth

    • C. 

      Cell division occurs by meiosis and binary fission

    • D. 

      Are common members of the resident microflora of the respiratory tract and skin

    • E. 

      Has inner and outer membranes, a periplasm, and a peptidoglycan cell wall

  • 20. 
    In diptheriae
    • A. 

      Alginate polysaccharide contributes to the formation of a pseudomembrane

    • B. 

      Protection is provided by the live BCG vaccine

    • C. 

      The diptheria toxin is a glycosidase that targets translation

    • D. 

      C.diptheriae is 'acid fast' due to its waxy impermeable cell envelope

    • E. 

      Protection is offered by a toxoid vaccine

  • 21. 
    Bacterial endotoxin
    • A. 

      Comprises variable sugars and protects against complement

    • B. 

      Is part of lipopolysaccharice in Staphylococcus aureus

    • C. 

      Is a PAMP that activates macrophages by CD14

    • D. 

      Can be made into a protective toxoid vaccine by heating

    • E. 

      Is actively secreted by the bacterial cell

  • 22. 
    Among antibiotics
    • A. 

      Sulphonamide blocks folate synthesis by inhibiting dihydrofolate reductase

    • B. 

      Tetracycline binds ribosomal 30S subunit

    • C. 

      Vancomycin mimics D-ala-D-ala crosslinks in peptidoglycan

    • D. 

      Ciprofloxacin and rifampicin block DNA replication

    • E. 

      Resistance to trimethoprim is mediated by enzyme inactivation

  • 23. 
    In gastrointestinal infections
    • A. 

      EHEC 0157 causes intoxication by producing superantigens in food

    • B. 

      ETEC causing travellers diarrhoea secretes a cholera-like ADP-ribosylating toxin

    • C. 

      Salmonella enteriditis causes gastroenteritis via chicken and eggs

    • D. 

      Shiga toxin causes haemolytic ureamia syndrome by ADP-ribosylating ribosomal proteins

    • E. 

      Staphylococcal food poisoning is thought to be caused by enterotoxins acting as superantigens

  • 24. 
    NK cells and interferon are the key elements of the innate defences against pathogenic bacteria
    • A. 

      True

    • B. 

      False

  • 25. 
    Lysozyme cleaves cell wall peptidoglycan
    • A. 

      True

    • B. 

      False

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