Antibiotic Review Part 2

22 Questions | By Robinson05 | Last updated: Mar 21, 2022 | Total Attempts: 112

Questions

Settings

Create your own Quiz

Part 2 of antibiotic review for PT3 good for Pharm D students

Questions and Answers

1.

This drug is effective against VRE and MRSA however it has a serious adverse effect of causing serious myalgias and arthralgias. It could also cause an increase in liver functions
- A.
  
  Quinupristin/Dalfopristin
- B.
  
  Linezolid
- C.
  
  Daptomycin
- D.
  
  Tigecycline
2.

This drug is effective against VRE and MRSA and can be given IV or PO giving it the ability to be used in the community setting. One problem with this well tolerated drug is that is extremely expensive
- A.
  
  Tigecycline
- B.
  
  Daptomycin
- C.
  
  Quinupristin/Dalfopristin
- D.
  
  Linezolid
3.

Patty Whitehair has been taking Linezolid for more then 14 days what adverse effect should she be monitored for?
- A.
  
  Thrombocytopenia
- B.
  
  Anemia
- C.
  
  Neutropenia
- D.
  
  Choices A and B
- E.
  
  All of the above
4.

This drug is only effective against gram + organisms and is effective against MRSA and VRE. It is limited to skin and skin structure infections. Qd dosing can cause skeletal muscle toxicity
- A.
  
  Quinupristin/Dalfopristin
- B.
  
  Tigecycline
- C.
  
  Daptomycin
- D.
  
  Linezolid
5.

Under what conditions should daptomycin be discontinued in patients?
- A.
  
  CPK 10 times the upper limit with no signs of myopathy
- B.
  
  CPK 5 times the upper limit with signs of myopathy
- C.
  
  CPK 2 times the upper limit with signs of mypothay
- D.
  
  Choice A and B
- E.
  
  Choice A and C
6.

What drug is effective against atypical organisms but not effective against organisms that have MDR-efflux pumps?
- A.
  
  Gentamicin
- B.
  
  Levofloxacin
- C.
  
  Tigecycline
- D.
  
  Azithromycin
7.

What statement are true about aminoglycosides?
- A.
  
  Drug that is active against MSSA and enterococcus spp. when in combination with a cell wall active agent.
- B.
  
  A drug that is seldom used alone always used in combination with a beta lactam drug.
- C.
  
  Aminoglycosides have no activity against gram - anaerobes
- D.
  
  All of the above a true
8.

This adverse effect of aminoglycosides is reversible and is usually resolved when the drug is stopped.
- A.
  
  Nephrotoxcity
- B.
  
  Ototoxicity
- C.
  
  All of the above
- D.
  
  None of the above
9.

Bob "buzz" party is a 75 year old who has a serous infection of P. aeruginosa when looking at his history you notice that Bob has cirrhosis due to his late nights partying when he was in the navy. You also notice from his lab result that his BUN is elevated above the UNL and when he was admitted he was taking Advil for his arthritis. How many risk factors does Bob have from nephrotoxcity if you choice to give him an aminoglycoside?
- A.
  
  1
- B.
  
  2
- C.
  
  3
- D.
  
  4
10.

Which fluoroquinolones has poor strep coverage but good pseudomonas activity and is effective against mycobacteria. It also usually needs renal adjustments.
- A.
  
  Levofloxacin
- B.
  
  Ciprofloxacin
- C.
  
  Moxifloxacin
- D.
  
  Gemifloxacin
11.

Which fluoroquinolones has enhanced activity against S. pneumoniae and is the preferred agent against Multi-drug resistant TB. This drug also need to be renally adjusted for kidney dysfunction.
- A.
  
  Levofloxacin
- B.
  
  Ciprofloxacin
- C.
  
  Moxifloxacin
- D.
  
  Gemifloxacin
12.

A patient asks when you given him his cirpofloxacin if it is okay if he takes it with milk? what would you tell him?
- A.
  
  Yeah it is okay ciprofloxacin is the only fluoroquinolone that you can take milk with it
- B.
  
  No, it is not okay because milk will coat the stomach preventing the absorption of the medication
- C.
  
  No, it is not okay the milk contain calcium and the metal would bind to the ciprofloxacin preventing it from being able perform its action
- D.
  
  It is fine to take milk with your medication and it will help to prevent an upset stomach.
13.

Ciprofloxacin is the least likely to cause what serious adverse effect compared to the other drug in its class?
- A.
  
  C.diff
- B.
  
  Tendinitis
- C.
  
  QT-prolongation
- D.
  
  None of the above
14.

Which drugs are considered macrolides?
- A.
  
  Erythromycin
- B.
  
  Clarithromycin
- C.
  
  Azithromycin
- D.
  
  All of the above
15.

What macrolide is not a P450 inhibitor?
- A.
  
  Erythromycin
- B.
  
  Azithromycin
- C.
  
  Clarithromycin
- D.
  
  None of the above all macrolides are P450 inhibitors
16.

Which of the following tetracyclines is recomended for the use against atypical infection chlamydia
- A.
  
  Doxycycline
- B.
  
  Minocycline
- C.
  
  Tigecycline
- D.
  
  Tetracycline
17.

Which drug has the best efficacy against anaerobes like B. fragilis
- A.
  
  Imipenem
- B.
  
  Clindamycin
- C.
  
  Metronidazole
- D.
  
  None of the above
18.

What drug is an option for patients that can't afford Linezolid for treatment of MRSA in the outpatient setting?
- A.
  
  Clindamycin
- B.
  
  Daptomycin
- C.
  
  Metronidazole
- D.
  
  None of the above Linezolid is the only choice
19.

Trimethoprim/sulfamethoxazole is good for many outpatient infection including what?
- A.
  
  VRE
- B.
  
  MRSA
- C.
  
  GISA
- D.
  
  All of the above
20.

This drug is for UTI only
- A.
  
  Metronidazole
- B.
  
  Colistin
- C.
  
  Clindamycin
- D.
  
  Nitrofurantoin
21.

What drug comes formulated as an IV and inhalant. Used primarily in cystic fibrosis patients with multidrug ressitant pseudomonas spp.
- A.
  
  Nitrofurantoin
- B.
  
  Trimethoprim/sulfamethoxazole
- C.
  
  Metronidazole
- D.
  
  Colistin
22.

What drug has to be dissolved in water and has a niche because it is safe to use in pregnant women with UTIs?
- A.
  
  Nitrofurantoin
- B.
  
  Colistin
- C.
  
  Fosphomycin tromethamine
- D.
  
  None of the above is safe to use in pregnant women