Antibiotic Review Part 1

29 Questions | By Robinson05 | Last updated: Mar 19, 2022 | Total Attempts: 419

Questions

Settings

Create your own Quiz

Antibiotic review for pharmacothreapy suitable for a pharm D level

Questions and Answers

1.

Which class of drugs fits this description " Activity against gram +, gram -, and some anaerobes. Split into 4 generations and has toxicity very similar to penicillin".
- A.
  
  Aminoglycosides
- B.
  
  Amino-penicillin
- C.
  
  Cephalosporins
- D.
  
  Carbapenems
2.

One advantage Cephalosporins is?
- A.
  
  Less expensive
- B.
  
  Has high efficacy against enterococcus sp.
- C.
  
  Not affected by resistant mechanisms
- D.
  
  Dosed less frequently
3.

Cephalexin is an example of what generation cephalosporins?
- A.
  
  Generation 1
- B.
  
  Generation 2
- C.
  
  Generation 3
- D.
  
  Generation 4
4.

This 1st generation cephalosporin is generally seen in the pre-op room because it is good for surgical prophylaxis
- A.
  
  Cephalexin
- B.
  
  Cefotaxime
- C.
  
  Cefazolin
- D.
  
  Cefotetan
5.

True or false 1st generation cephalosporins are good for infections of the CNS
- A.
  
  True
- B.
  
  False
6.

This cephalosporin is good alternative to a patient with a nafcillin allergy? (adjusted for renal dysfunction)
- A.
  
  Cephalexin
- B.
  
  Cefazolin
- C.
  
  Cefuroxime
- D.
  
  Cefaclor
7.

Which of the following are 2ed generation cephalosporin?
- A.
  
  Cefaclor
- B.
  
  Cefotetan
- C.
  
  Cefuroxime
- D.
  
  All of the above
8.

What 2ed generation cephalosporin is used for upper respiratory infections, UTIs, and skin/skin structure infections?
- A.
  
  Cefuroxime
- B.
  
  Cefoxitin
- C.
  
  Cefotetan
- D.
  
  Cefmetazole
9.

Which of the following are considered cefamycins due to there effectiveness against the anaerobic bacteria B. fragilis
- A.
  
  Cefotetan
- B.
  
  Cefoxitin
- C.
  
  Cefmetazole
- D.
  
  All of the above
10.

Sally Mcfatten is finally getting the gastric bypass she has always wanted what would be a good cephalosporin to use before her surgery for prophylaxis.
- A.
  
  Cefazolin
- B.
  
  Cefotetan
- C.
  
  Cefuroxime
- D.
  
  None of the above
11.

Which of the following is/are examples of 3rd generation cephalosporins?
- A.
  
  Cefotaxime
- B.
  
  Ceftriaxone
- C.
  
  Ceftazidime
- D.
  
  All of the above
12.

Which 3rd generation cephalosporin is the drug of choice for S. pneumoniae
- A.
  
  Ceftriaxone
- B.
  
  Ceftazidime
- C.
  
  Cefixime
- D.
  
  None of the above
13.

What cephalosporin would be a good choice for someone with a CNS infection?
- A.
  
  Ceftriaxone
- B.
  
  Cephalexin
- C.
  
  Cefazolin
- D.
  
  All of the above
14.

Ceftazidime is the only 3rd generation cephalosporin with activity against what organism
- A.
  
  MSSA
- B.
  
  MRSA
- C.
  
  Pseudomonas
- D.
  
  All of the above
15.

Cefepime is in what generation of cephalosporins?
- A.
  
  Generation 1
- B.
  
  Generation 2
- C.
  
  Generation 3
- D.
  
  Generation 4
16.

Cefepime has activity against what microbes?
- A.
  
  Pseudomonas
- B.
  
  MSSA
- C.
  
  S. epidermidis
- D.
  
  Choice A and B
- E.
  
  All of the above
17.

Imipenem, Meropenem, Ertapenem and Doripenem all belong to what class of antibiotic?
- A.
  
  Aminoglycocide
- B.
  
  Carbapenems
- C.
  
  Macrolides
- D.
  
  Fluoroquinolones
18.

Which drug falls under the description " extremely broad spectrum activity including gram +, gram -, anaerobes and considered in serious nosocomial infections".
- A.
  
  Imipenem
- B.
  
  Vancomycin
- C.
  
  Aztreonam
- D.
  
  Linezolid
19.

Why is Imipenem co-formulated with cilastatin?
- A.
  
  To enhance the effect of the drug
- B.
  
  To inhibit the tubular excretion of the drug
- C.
  
  To increase the drugs bioavailability
- D.
  
  To inhibit dehydropeptidase-1
20.

True or False when using a carbapenem it is necisaary to dose adjust with CrCl <50ml/min
- A.
  
  True
- B.
  
  False
21.

Which drug class has no effect against gram + organisms
- A.
  
  Vancomycin
- B.
  
  Aztreonam
- C.
  
  Aminoglycosides
- D.
  
  Carbapenem
22.

Which type of beta lactam allergy is due to the formation of immune complexes?
- A.
  
  Type 1
- B.
  
  Type 2
- C.
  
  Type 3
- D.
  
  Type 4
23.

Which type of beta lactam allergy is due to a IgE mediated response?
- A.
  
  Type 1
- B.
  
  Type 2
- C.
  
  Type 3
- D.
  
  Type 4
24.

True or false patients with beta lactam allergies have the greatest cross reactivity with 3rd generation cephalosporins
- A.
  
  True
- B.
  
  False
25.

Which of the following is the drug of choice for treating MRSA infections?
- A.
  
  Vancomycin
- B.
  
  Tobramycin
- C.
  
  Gentamicin
- D.
  
  Linezolid