1.
What is the name of the specialized dendritic cells that are found on the skin surface?
Correct Answer
C. Langerhans cell
Explanation
Langerhans cells are specialized dendritic cells that are found on the skin surface. They play a crucial role in the immune system by capturing antigens and presenting them to T cells, initiating an immune response. Unlike other dendritic cells, Langerhans cells are unique to the skin and are named after the German physician Paul Langerhans, who first described them in 1868.
2.
Immature dendritic cells are also called ________________.
Correct Answer
A. Veiled cells
Explanation
Immature dendritic cells are referred to as veiled cells. This term is used to describe their appearance, as they have long, thin extensions that cover their surface, giving them a "veiled" or "veil-like" appearance. This stage is characterized by the cells' ability to capture antigens but not yet fully activate the immune response. Once mature, dendritic cells lose their veil-like extensions and become more active in presenting antigens to other immune cells.
3.
Dendritic cells are derived from what type of cells?
Correct Answer
D. Hematopoietic bone marrow progenitor cells
Explanation
Dendritic cells are derived from hematopoietic bone marrow progenitor cells. Hematopoietic stem cells in the bone marrow give rise to various types of blood cells, including dendritic cells. Dendritic cells play a crucial role in the immune system, acting as antigen-presenting cells and initiating immune responses.
4.
Which organ produces the dendritic cells?
Correct Answer
A. Bone marrow
Explanation
Dendritic cells are a type of immune cell that play a crucial role in initiating and regulating immune responses. They are primarily produced in the bone marrow, which is the site of hematopoiesis, the process of generating all types of blood cells including immune cells. Dendritic cells are then distributed throughout the body, where they function as antigen-presenting cells and help activate other immune cells. Tonsils and brain do not produce dendritic cells.
5.
Who coined the term Dendritic cells?
Correct Answer
C. Ralph M. Steinman
Explanation
Ralph M. Steinman is credited with coining the term "Dendritic cells."
6.
Where are the cells commonly found?
Correct Answer
D. All of the above
Explanation
Cells are commonly found in various parts of the body, including the skin surface, linings of the nose, and gastrointestinal tract. These locations are known to have a high concentration of cells due to their role in protecting the body, providing sensory functions, and aiding in digestion. Therefore, the correct answer is "All of the above."
7.
What was Conventional dendritic cells (cDC) previously called?
Correct Answer
D. Myeloid dendritic cell (mDC)
Explanation
Conventional dendritic cells (cDC) were previously called Myeloid dendritic cells (mDC).
8.
When were the cells discovered?
Correct Answer
B. 1973
Explanation
The cells were discovered in 1973.
9.
What do Conventional dendritic cells (cDC) secrete?
Correct Answer
D. All of the above
Explanation
Conventional dendritic cells (cDC) secrete various substances, including Interleukin 12, Interleukin 6, and chemokines. Interleukin 12 is a cytokine that plays a crucial role in immune responses, promoting the differentiation of T cells into Th1 cells. Interleukin 6 is another cytokine involved in immune regulation, inflammation, and hematopoiesis. Chemokines are small proteins that help in immune cell migration and recruitment to sites of infection or inflammation. Therefore, cDCs secrete all of these substances, contributing to the immune response and regulation.
10.
__________________________ is secreted by Plasmacytoid dendritic cells (pDC).
Correct Answer
B. Interferon-α
Explanation
Interferon-alpha is secreted by Plasmacytoid dendritic cells (pDC). It is a type of cytokine that plays a critical role in the immune response against viral infections. Interferon-alpha helps to activate other immune cells, such as natural killer cells and cytotoxic T cells, to destroy virus-infected cells. It also stimulates the production of antibodies and enhances the presentation of antigens to other immune cells. Overall, Interferon-alpha is an important component of the body's defense mechanism against viral pathogens.