What does the nurse expect to administer to reverse the hypertensive crisis caused by pheochromocytoma?
A client with a history of pheochromocytoma is admitted to the hospital in an acute hypertensive crisis.
Change Image Delete
A. Phentolamine (Regitine). B. Methyldopa (Aldomet). C. Mannitol (Osmitrol). D. Felodipine (Plendil).
The correct answer to this question is option A - Phentolamine (Regitine) Pheochromocytoma is a tumor of the adrenal glands. A patient with this medical condition can experience a hypertensive crisis. Hypertensive crisis is a rapid and severe increase in blood pressure with readings of 180/120 or higher.
In Pheochromocytoma, there is the excess release of adrenaline (epinephrine and norepinephrine) in the blood, which rapidly raises blood pressure. Phentolamine (Regitine) is used to reverse the hypertensive crisis caused by pheochromocytoma. It is a reversible, nonselective α-adrenergic receptor blocker.
This antagonizes the effect of adrenaline in the body. It effectively reduces blood pressure in a short period of time. Methyldopa (Aldomet), Mannitol (Osmitrol), and Felodipine (Plendil) are also antihypertensive agents, but they are not the drug of choice to treat hypertensive crisis in Pheochromocytoma.
The answer is A. When treating a client with a history of pheochromocytoma who has been admitted to the hospital in an acute hypertensive crisis, the nurse should expect to administer Phentolamine (Regitine) to reverse the hypertensive crisis caused by pheochromocytoma.
This condition occurs when the adrenal glands in the kidneys release too much adrenaline which is also called epinephrine and norepinephrine. When this happens, it causes the client's blood pressure to get very high. Phentolamine is given by an IV infusion and reduces the client's blood pressure quickly. That is why this is the correct answer choice for this question.
Phentolamine (regitine).-rationale: pheochromocytoma causes excessive production of epinephrine and norepinephrine, natural catecholamines that raise the blood pressure. phentolamine, an alpha-adrenergic given by i.v. bolus or drip, antagonizes the bodys response to circulating epinephrine and norepinephrine, reducing blood pressure quickly and effectively. although methyldopa is an antihypertensive agent available in parenteral form, it isnt effective in treating hypertensive emergencies. mannitol, a diuretic, isnt used to treat hypertensive emergencies. felodipine, an antihypertensive agent, is available only in extended-release tablets and therefore doesnt reduce blood pressure quickly enough to correct hypertensive crisis.client needs category: physiological integrityclient needs subcategory: pharmacological and parenteral therapiescognitive level: applicationreference: smeltzer, s.c., et al. brunner and suddarths textbook of medical surgical-nursing, 11th ed. philadelphia: lippincott williams & wilkins, 2008, p. 1476.