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Which of the following is the most likely cause of this man’s symptoms? A 40-year-old man presents to his physician with sharp, sudden, sporadic pain in his lower back and hematuria. His blood pressure is normal and his physical examination is significant for flank pain. A plain film of the pelvis does not show any renal calculi.



A. Hyperparathyroidism
B. Hyperuricemia
C. Infection with Proteus vulgaris
D. Prostate cancer
E. Staphylococcal infection

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Step 1 First Aid Renal System prt l
Asked by Bromley, Last updated: Mar 18, 2020

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3 Answers

C.Charlotte

C.Charlotte

Answered Feb 10, 2020

Hyperuricemia is a condition that occurs when there is too much uric acid in your blood. Increased uric acid levels are correlated with kidney disease. Hyperuricemia also occurs when the body cannot excrete enough uric acid. Generally, this happens when your kidneys can’t get rid of enough waste. Excess uric acid levels in your blood might lead to the formation of crystals.

These tend to develop around your kidneys and joints. The crystals that are produced in your body may attack your white blood cells, causing pain and inflammation. Hematuria is a particular symptom, which can also be caused by hyperuricemia.

 

Amla Amelia

Amla Amelia

Answered Feb 07, 2020

The correct answer to this question is B, Hyperuricemia. This condition leads to kidney stones. When these kidney stones occur, they are radiolucent and not seen on X-rays. These kidney stones are often the setting of diseases that have turnover and cell proliferation, like myeloproliferative disorders and leukemia. Hyperuricemia is known as having high uric acid levels.

There are two types to this condition, which are primary and secondary. Primary is when there are increased uric acid levels, which are due to purine. Then, there is secondary, which is due to diseases. This condition is normally the result of the body producing more uric acid than it can rid itself of.

 

John Smith

John Smith

Answered Sep 09, 2016

Hyperuricemia-the correct answer is b. normally hyperuricemia leads to kidney stones that are radiolucent and therefore not seen on x-ray. these stones are often seen in the setting of diseases with increased cell proliferation and turnover, such as leukemia and myeloproliferative disorders. remember that uric acid is a metabolite of nucleic acid turnover, which is heightened in the setting of cell destruction.answer a is incorrect. calcium stones are the most common cause of kidney stones (80% 85%). therefore, states that lead to increased calcium (e.g., hyperparathyroidism, destructive bone diseases) can lead to their formation. the stones are made of calcium oxalate or calcium phosphate and are radiopaque. other risk factors are increased vitamin d and milk-alkali syndrome.answer c is incorrect. urinary tract infection with urease-positive microorganisms such as proteus vulgaris and staphylococcus saprophyti- cus can form large struvite calculi (ammonium, magnesium, and phosphate) that are usually (80%) radiopaque. this is the second most common cause of kidney stones.answer d is incorrect. prostate cancer commonly sends metastases to the bone, the destruction of which leads to a hypercalcemic state and the production of radiopaque calcium- based stones.answer e is incorrect. urinary tract infection with urease-positive microorganisms such as staphylococcus saprophyticus can form large struvite calculi that are radiopaque.
 

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