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Which of the following raises the most concern about the validity of the conclusion that vitamin C supplements prevent the common cold? A study is conducted to assess the effectiveness of vitamin C in preventing common colds in children, Patients are randomly assigned to receive either vitamin C or no intervention. Outcome events (common cold) are reported by the parents on a monthly basis for 1 year. Results show that those taking vitamin C have fewer colds compared with those who received no intervention (p<0.05).



A. Inadequate statistical power
B. Non-randomization
C. Selection bias
D. Variability in outcome assessment

This question is part of NBME 13 section 1 (qst 1-50)
Asked by Wyatt Williams, Last updated: Aug 02, 2020

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3 Answers

R. Hunter

R. Hunter

Answered Jul 05, 2020

The correct answer to this question is D, Variability in outcome assessment. In the question provided, the focus is on the relationship between Vitamin C intake and common colds. For centuries, medical experts have advised that to reduce the risk of a common cold, a person should increase their intake of Vitamin C.

The assessment in the question was used to check the advice that many people follow. It has shown that the advice is accurate, for those that had Vitamin C had fewer colds. This was compared to those who did not intake Vitamin C and had more colds.

 

Samantha Stewart

Love to do some charity work. Have a passion for writing and do it in my spare time

Samantha Stewart, Philanthropist, Post Graduate, Corpus Christi

Answered Jan 28, 2019

Since we were born, we have always been told to drink orange juice because of the vitamin C. The vitamin C always helps get rid of and prevents colds. However, that seems like a myth. Many times, I have been drinking orange juice every day and still get a cold. Vitamin C being a cure for the common cold is simply a myth, but it does have other benefits including eye problems and skin wrinkling.

Zinc seems to be the element that helps prevent people from getting the common cold. The variability in outcome assessment raises the most concern about the validity of the conclusion that vitamin C supplements prevent the common cold. However, you should continue to bring in vitamin C.

 

Wyatt Williams

Wyatt Williams

Answered Oct 18, 2017

Variability in outcome assessment
 

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