Which of the following choices best describe the changes in the concentration of chorionic gonadotropin (hCG) during pregnancy?
A. HCG peak is at ~10 weeks of gestation B. HCG peak is at ~20 weeks of gestation C. HCG peak is at ~30weeks of gestation D. HCG nadir is at ~10 weeks of gestation E. HCG nadir is at ~20 weeks of gestation F. HCG nadir is at ~30 weeks of gestation
Hcg peak is at ~10 weeks of gestation-the concentration of hcg peaks approximately at the end of the first trimester, declines,and then remains stable throughout the remainder of gestation. levels of hcg typically start to fallafter the luteal placental shift - placental progesterone is thought to inhibit the production of hcg.there is no true nadir in hcg - the lowest levels are seen during the first 2 weeks of pregnancy,during implantation when the blastocyst is invading the endometrium. levels of hcg will fallapproximately 2-4 weeks after birth and delivery of the baby and placenta.