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Which of the following drugs, given locally, would be appropriate for this patient?
A 32-year-old woman presents to her gynecologist with a 4 days history of perineal pruritus and a non-malodorous, thick, cheesy vaginal discharge. The only medication the woman is taking is an oral contraceptive. A wet preparation of vaginal secretion shows budding yeast cells and pseudohyphae.



A. Mebendazole
B. Metronidazole
C. Miconazole
D. Zidovudine
E. Griseofulvin
F. Saquinavir

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Block 15 Pharm antifungal drugs
Asked by Ruby, Last updated: Jun 15, 2020

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1 Answer

John Smith

John Smith

Answered Sep 09, 2016

Miconazole-answer: c the symptoms of the patient and the lab results strongly suggest that she is suffering from genital candidiasis, the most common opportunistic mycosis of genital tract in women taking oral contraceptives. other predisposing factors include pregnancy, menstruation, diabetes mellitus, and use of broad-spectrum antibiotics, corticosteroids, or immunosuppressive drugs. budding yeast cells and pseudohyphae of candida albicans ( the most common candida species causing candidiasis), can be detected by microscopic examination of biologic specimens. candida albicans is sensitive to most antifungal drugs, but for genital candidiasis a topical azole derivative (miconazole, ketoconazole, etc. ) or topical nystatin are the treatments of choice. a, b, d) these agents are not antifungal drugs. e, f) these antifungal drugs are not effective against candida albicans.
 

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