Receptors located on CNS nerve terminals can be autoreceptors or - ProProfs
     

Receptors located on CNS nerve terminals can be autoreceptors or heteroreceptors. Which of the following descriptions refers to heteroreceptors? (Check all that apply)



A. 5-HT1A receptors on nerve terminals of most neurons of Raphe Nucleus
B. M2 cholinergic receptors on the motor nerve terminals
C. Alpha-2 receptors on nerve terminals of most neurons of Locus Ceruleus
D. D2 receptors on nerve terminals of nigrostriatal pathway
E. GABA A receptors on nerve terminals of cortical pyramidal neurons
F. Glutamate receptors on nerve terminals mesolimbic pathway

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John Smith

John Smith

Answered on Sep 09, 2016

1. gaba a receptors on nerve terminals of cortical pyramidal neurons-2. glutamate receptors on nerve terminals mesolimbic pathway-answer: ef(katzung, pp 88, brunton, pp 148)by definition heteroreceptors are receptors located on nerve terminals that regulate therelease of a transmitter different from the one that activate them, whereas autoreceptors arereceptors located on nerve terminals that regulate the release of the transmitter which activatethem. cortical pyramidal neurons are glutamatergic and therefore gaba a receptors located onnerve terminal of those neurons are heteroreceptors. neurons of the mesolimbic pathway aredopaminergic and therefore glutamate receptors located on nerve terminal of those neuronsare heteroreceptors.a) most neurons of the raphe nucleus are serotonergic an therefore 5-ht1a receptors onnerve terminals of most neuronsb) motor neurons are cholinergic and therefore m2 receptors located on nerve terminal ofthose neurons are autoreceptors.c) most neurons of locus ceruleus are noradrenergic and therefore alpha-2 receptors locatedon nerve terminal of those neurons are autoreceptors.d) neurons of the mesolimbic pathway are dopaminergic and therefore d2 receptors locatedon nerve terminal of those neurons are autoreceptors.

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