A 32 year old man, recently diagnosed with partial seizure, started a - ProProfs
     

A 32-year-old man, recently diagnosed with partial seizure, started a treatment with felbamate, a drug that is thought to act by blocking NMDA receptors in the brain. Which of the following systems was most likely affected by the drug?



A. Noradrenergic
B. Cholinergic
C. Histaminergic
D. Dopaminergic
E. Serotonergic
F. GABAergic
G. Glutamatergic

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1 Answer

John Smith

John Smith

Answered on Sep 09, 2016

Glutamatergic-answer: g (katzung, pp 385, brunton pp 520) glutamate is important excitatory neurotransmitter in the brain. glutamate receptors include nmda and ampa receptors. drugs, like felbamate, that seem to act by blocking these receptors can be used effectively as anticonvulsants. a, b, c, d, e) these systems are not exclusively excitatory and therefore drugs affecting these systems are not used as anticonvulsants. g) the gabaergic system is a central inhibitory system. drugs that increase the activity of this system (like benzodiazepines and barbiturates) are currently used as anticonvulsants.

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