Which of the following drugs did the patient most likely take? - ProProfs Discuss
Topics
Products
Follow Us:

Which of the following drugs did the patient most likely take?
A 39-year-old man, diagnosed with tonic-clonic seizures two years ago, had been receiving a drug that exhibits a dose-dependent elimination kinetics.



A. Valproic acid
B. Lamotigrine
C. Phenytoin
D. Topiramate
E. Carbamazepine
F. Gabapentin

This question is part of block 13 pharm antiseizure drugs

Asked by Daisy, Last updated: Aug 02, 2020

+ Answer
Request

1 Answer

John Smith

John Smith

Answered Sep 09, 2016

Phenytoin-answer: cphenytoin is one of the very few drugs that exhibits first order elimination kinetics at low dosesbut switches to a zero order elimination kinetics at higher doses, that is the elimination kineticsof the drug is dose-dependent. important consequence of dose-dependent kinetics are:a) the clearance and the half life of the drug are dose-dependent.b) the time taken to reach steady state is also dose dependent, and therefore cannot bepredicted.c) a slight increase in dose can have a big effect on plasma levels, so leading to toxicity.a, b, d, e, f) all these drugs follow a first order elimination kinetics.
 

Search for Google images
Select a recommended image
Upload from your computer
Search for Google images
Select a recommended image
Upload from your computer
Search for Google images
Select a recommended image
Upload from your computer

Email Sent
We have sent an email to your address "" with instructions to reset your password.