A 25-year-old man was accompanied to the clinic by his mother who stated that her son had been exhibiting most unusual behavior over the last few weeks. He was euphoric most of the day, stayed up later and later at night, and frequently awakened his parents shouting and screaming. Recently he experienced problems at work. Upon arriving at the clinic he had trouble sitting still or listening and became increasingly irritable throughout the examination. He repeatedly said he heard a voice telling him he had a superpower.
Which of the following pairs of drugs would be most helpful for the patient’s condition?
A. Fluoxetine and risperidone B. Imipramine and lithium C. Fluoxetine and haloperidol D. Imipramine and haloperidol E. Risperidone and lithium
Risperidone and lithium-learning objective: outline the therapeutic uses of lithium.answer: ethe symptoms and signs of the patient suggest that he is suffering from an acute manicdisorder. lithium is the drug of choice for bipolar disorders, since it reduces both the frequencyand the magnitude of mood swings. however it has a slow onset of action, taking as long as 1to 2 weeks to fully exert its therapeutic effects. therefore an adjunctive medication is usedduring the first days of therapy. benzodiazepines are used for agitation and insomnia butatypical neuroleptics are preferred when there are delusions or hallucinations, like in thepresent case.a, b, c, d) all these combinations have at least one drug that is not effective in manicdisorders.