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What is the most likely diagnosis for a 4-year-old girl who has complained of abdominal pain for the past month?
On physical examination, she is febrile, and palpation of the abdomen shows a tender mass on the right. Bowel sounds are present. Laboratory studies show hematuria without proteinuria. Abdominal CT scan shows a 12-cm, circumscribed, solid mass in the right kidney. A right nephrectomy is done; the gross appearance of the mass is shown in the figure.

What is the most likely diagnosis for a 4-year-old girl who has complained of abdominal pain for the past month?<br/>On physical examination, she is febrile, and palpation of the abdomen shows a tender mass on the right. Bowel sounds are present. Laboratory studies show hematuria without proteinuria. Abdominal CT scan shows a 12-cm, circumscribed, solid mass in the right kidney. A right nephrectomy is done; the gross appearance of the mass is shown in the figure.

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A. Angiomyolipoma
B. Interstitial cell tumor
C. Renal cell carcinoma
D. Transitional cell carcinoma
E. Wilms tumor
Asked by Jayden, Last updated: Jun 02, 2020

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John Smith

John Smith

Answered Sep 09, 2016

Wilms tumor-(e) wilms tumor is the most common renal neoplasm in children, and one of the most common childhood neoplasms. a complex staging, grading, and molecular analysis formula, and surgery, chemotherapy, and radiation result in a high cure rate. the microscopic pattern of wilms tumor (nephroblastoma) resembles the fetal kidney nephrogenic zone. angiomyolipomas may be sporadic or part of the genetic syndrome of tuberous sclerosis. they may be multiple and bilateral and have well-differentiated muscle, adipose tissue, and vascular components. renomedullary interstitial cell tumors (medullary fibromas) are generally less than 1 cm and are incidental findings. renal cell carcinoma is rare in children, and the most common patterns are clear cell, papillary, and chromophobe. transitional cell carcinomas arise in the urothelium in adults and microscopically resemble urothelium. bp7 256257, 541bp8 271273pbd7 504506pbd8 479481
 

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